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Mechanisms of Endocytosis and Membrane Trafficking in Neurons
Submission Deadline: Apr. 30, 2020

This special issue currently is open for paper submission and guest editor application.

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Lead Guest Editor
Enrico Castroflorio
Department of Mammalian Genetics Unit, Medical Research Council Harwell Institute, Oxfordshire, UK
Guest Editors
  • Davide Aprile
    Department of Experimental Medicine, Section of Human Physiology, University of Genova, Genoa, Italy
  • Alessandro Esposito
    Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Genoa, Italy
  • Erica Tagliatti
    University College London, London, UK
  • Edoardo Moretto
    Dementia Research Institute, University College London, London, UK
  • Antonio De Fusco
    Department of Experimental Medicine, Section of Human Physiology, University of Genova, Genoa, Italy
  • Marta Orlando
    Neurowissenschaftliches Forschungszentrum, Charité Universitätsmedizin, Berlin, Germany
Guidelines for Submission
Manuscripts can be submitted until the expiry of the deadline. Submissions must be previously unpublished and may not be under consideration elsewhere.
Papers should be formatted according to the guidelines for authors (see: http://www.sciencepublishinggroup.com/journal/guideforauthors?journalid=111). By submitting your manuscripts to the special issue, you are acknowledging that you accept the rules established for publication of manuscripts, including agreement to pay the Article Processing Charges for the manuscripts. Manuscripts should be submitted electronically through the online manuscript submission system at http://www.sciencepublishinggroup.com/login. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal and will be listed together on the special issue website.
Published Papers
The special issue currently is open for paper submission. Potential authors are humbly requested to submit an electronic copy of their complete manuscript by clicking here.

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Special Issue

Introduction
Endocytosis is a fundamental mechanism by which all eukaryotic cells control their plasma membrane composition. Membrane recycling allows cells to control several processes, including cell signaling, cell adhesion, and cell-cell communication. Endocytic mechanisms involve a broad range of protein-protein and protein-phospholipid interactions that regulate the formation of endocytic structures like vesicles, tubules, and endosomes that can either redirect cargoes to the plasma membrane or sent them to multi-vesicular bodies for degradation. These pathways are possible thanks to a remarkable diversity of endocytic routes and molecular players that strictly regulate membrane trafficking inside the cell. In neuronal cells endocytosis is essential for the recycling of membrane after neurotransmitter release and plays a critical role during early developmental stages. Moreover, alterations of the endocytic pathway have been attributed a crucial role in the pathophysiology of several neurological diseases ranging from epilepsy and autism to storage disorders and neurodegeneration. Although well characterized at the ultrastructural level, little is known of the dynamics and molecular organization of the neuronal endocytic pathways. In our special issue entitled “Mechanisms of Endocytosis and Membrane Trafficking in Neural Cells”, we propose to share the recent advances regarding the molecular mechanisms of endocytosis and organelle trafficking in neuronal cells and the development of new tools to investigate them.
Aims and Scope:
  1. Endocytosis
  2. Membrane trafficking
  3. Membrane transport
  4. Molecular machinery
  5. Vesicles organization
  6. Intraluminal pH
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