School of Medicine (Biochemistry Unit), Hawassa University College of Medicine and Health Sciences,
Hawassa, SNNPR, Ethiopia
School of Medicine, Biomedical Department, Arbaminch University College of Health Sciences
Belayhun Kibret Temesgen
School of Medicine, Biochemistry Unit, Hawassa University College of Medicine and Health Sciences
Biochemistry Department, Addis Ababa University College of Health Sciences
Addis Ababa, Ethiopia
Endocrine disorders are the major health problems that affect lives in both developing and developed countries. The most common types of endocrine disorders are diabetes, thyroid dysfunction, and disorders related to steroid hormones. Diabetes, the commonest disease of endocrine system, is encroaching the lives of people in developed and developing countries, in rural and urban settings. According to IDF report in 2015 about 415 million people have diabetes worldwide and estimated to affect lives of about 642 million people in 2o40. The other challenging truth of diabetes is that it affects people of productive age. Therefore, detail mechanisms of pathogenesis has to be delineated to take rigorous actions to prevent, diagnose, manage, and treat diabetes and its complications. Significant number of people are suffering from thyroid disorders, with hypothyroidism being more prevalent than hyperthyroidism. It has been well established that thyroid dysfunction during pregnancy is associated with adverse outcomes on the offspring and the mother’s life. Therefore, proper interpretation of thyroid function tests during pregnancy is vitally important for appropriate management of thyroid disorders during pregnancy to reduce the adverse outcomes. For proper interpretation of thyroid function tests during pregnancy use of trimester-specific reference ranges are recently recommended by different studies.
Aim: To disseminate current updates and innovations in terms of prevention, diagnosis, understanding the mechanism of pathogenesis and treatment regimens in the mentioned endocrine disorders and others to academicians, researchers, physicians, and students.
Prevalence of diabetic complications The role of oxidative stress and inflammatory mediators in the development of complications of diabetes Mechanism of beta-cell destruction Investigation of biomarkers for insulin resistance and early detection of type 2 diabetes Genetic predisposition for development and complication of type 2 diabetes Treatment regimens and their outcomes Prevalence of thyroid dysfunction in general populations and specific population groups Trimester specific reference ranges of thyroid function tests Metabolic changes related to hyperthyroidism and hypothyroidism