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Home / Journals Science Journal of Public Health / Obstructive Sleep Apnea: A Systemic Disease
Obstructive Sleep Apnea: A Systemic Disease
Submission Deadline: Feb. 28, 2016
Lead Guest Editor
Professor Aliae AR Mohamed-Hussein
Chest Department, Assiut University Hospitals, Assiut, Egypt
Guest Editors
  • Klaus Dulhoff
    Pulmonology Department, Medical University of Lubeck, Lubeck, Germany
  • Tenor Henning Koth
    Pulmonology Department, Medical University of Lubeck, Lubeck, Germany
  • Andreas Rembert Koczulla
    Pulmonology Department, Marburg University, Marburg, Germany
  • Roland Buhl
    Pulmonary Department, Mainz University Hospital, Mainz, Germany
  • Ayman Khairy
    Cardiology Department, Assiut University Hospitals, Assiut, Egypt
  • Professor Sherifa Hamed
    Department of Neurology and Psychiatry, Assiut University Hospital, Assiut, Egypt
  • Hossam Gendi
    Essex Cardiac Center, Princess Alexandra Hospital, London, UK
  • John Moxham
    Physiology Department, Kings College London, London, UK
  • Micheal Polkey
    Physiology Department, Imperial College London, London, UK
  • Yoshino Ichiro
    Pulmonology Department, Chiba University, Chiba, Japan
  • Jafar Al-Sharab
    Northwestern State University, Las Vegas, Nevada, USA
  • Mohammed Obeidat
    Jordan University of Science and Technology, Amman, Jordan
  • Obair Siddiqui
    LG Electronics Inc., Detroit, Michigan, USA
Guidelines for Submission
Manuscripts can be submitted until the expiry of the deadline. Submissions must be previously unpublished and may not be under consideration elsewhere.
Papers should be formatted according to the guidelines for authors (see: By submitting your manuscripts to the special issue, you are acknowledging that you accept the rules established for publication of manuscripts, including agreement to pay the Article Processing Charges for the manuscripts. Manuscripts should be submitted electronically through the online manuscript submission system at All papers will be peer-reviewed. Accepted papers will be published continuously in the journal and will be listed together on the special issue website.
Published Papers
Authors: Sherifa Ahmed Hamed
Pages: 6-16 Published Online: Sep. 8, 2015
Views 8634 Downloads 240
Authors: Aliae AR Mohamed-Hussein, Mohamed-Eltaher AA Ibrahim
Pages: 1-5 Published Online: Sep. 8, 2015
Views 4554 Downloads 159
Obstructive sleep apnea syndrome (OSAS) is a highly prevalent sleep disorder, characterized by repeated disruptions of breathing during sleep. This disease has many potential consequences including excessive daytime sleepiness, neurocognitive deterioration, endocrinologic and metabolic effects, and decreased quality of life. Metabolic syndrome is another highly prevalence emerging public health problem that represents a constellation of cardiovascular risk factors. Each single component of the cluster increases the cardiovascular risk, but the combination of factors is much more significant. It has been suggested that the presence of OSAS may increase the risk of developing some metabolic syndrome features. Moreover, OSAS patients are at an increased risk for vascular events, which represent the greatest morbidity and mortality of all associated complications.

Although the etiology of OSAS is uncertain, intense local and systemic inflammation is present. A variety of phenomena are implicated in this disease such as modifications in the autonomic nervous system, hypoxemia–reoxygenation cycles, inflammation, and coagulation–fibrinolysis imbalance. OSAS patients also present increased levels of certain biomarkers linked to endocrine-metabolic and cardiovascular alterations among other systemic consequences.

The Aim of this Special issue is to clarify that OSAS is more than a local abnormality, and it should be considered a systemic disease.
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