Prescribing Anticholinergic Medication in Neurocognitive Disorders: Pharmacological Implications and Clinical Proofs
American Journal of Psychiatry and Neuroscience
Volume 5, Issue 6-1, November 2017, Pages: 14-14
Received: Oct. 10, 2017; Accepted: Oct. 12, 2017; Published: Oct. 13, 2017
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Authors
Bogdan Mircea Petrescu, Psychiatry Clinic, Central Military Emergency University Hospital “Dr. Carol Davila”, Bucharest, Romania
Alina Mitrache, Psychiatry Clinic, Central Military Emergency University Hospital “Dr. Carol Davila”, Bucharest, Romania
Daniel Vasile, Psychiatry Clinic, Central Military Emergency University Hospital “Dr. Carol Davila”, Bucharest, Romania
Octavian Vasiliu, Psychiatry Clinic, Central Military Emergency University Hospital “Dr. Carol Davila”, Bucharest, Romania
Andrei Gabriel Mangalagiu, Psychiatry Clinic, Central Military Emergency University Hospital “Dr. Carol Davila”, Bucharest, Romania
Cristian Alexandru Cândea, Psychiatry Clinic, Central Military Emergency University Hospital “Dr. Carol Davila”, Bucharest, Romania
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Abstract
The use of anticholinergic medicines is a widespread practice in older adults. Numerous studies have emphasized that the use of anticholinergics can be associated with a high risk of developing dementia. The aim of this analysis is to describe pharmacologically the interactions and effects of the use of anticholinergics in neurocognitive disorders and to offer practical advice for limiting or even avoiding altogether using this type of medicines when the risks are greater than the benefits.
In conclusion, there is evidence suggesting that the anticholinergic medicines can increase the risk of dementia. Considering this potential risk and the multitude of well-known adverse effects (constipation, diplopia, urinary retention and delirium) associated with the anticholinergic medicines, it is prudent to limit their use and consider possible alternatives.
Keywords
Neurocognitive Disorders, Anticholinergics
To cite this article
Bogdan Mircea Petrescu, Alina Mitrache, Daniel Vasile, Octavian Vasiliu, Andrei Gabriel Mangalagiu, Cristian Alexandru Cândea, Prescribing Anticholinergic Medication in Neurocognitive Disorders: Pharmacological Implications and Clinical Proofs, American Journal of Psychiatry and Neuroscience. Special Issue: “In and out of Your Mind” Abstracts of 1st Eastern European Conference of Mental Health. Vol. 5, No. 6-1, 2017, pp. 14-14. doi: 10.11648/j.ajpn.s.2017050601.24
Copyright
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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