Chemical Preparation of Iron Oxide Nanoparticles Using Plants Extracts in Antibacterial Application
International Journal of Bioorganic Chemistry
Volume 4, Issue 1, June 2019, Pages: 1-6
Received: Feb. 2, 2019; Accepted: Mar. 11, 2019; Published: Mar. 26, 2019
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Wisam Jafer Aziz, Department of Physics, College Science, Mustansiriyah University, Baghdad, Iraq
Aliyaa Abd Urabe, Department of Physics, College Science, Mustansiriyah University, Baghdad, Iraq
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In of this studying the green synthesis of Iron Oxide nanoparticles (Fe2O3 NPs) with Celery stalks and green tea leaves extract were used. The fresh suspension of plant extracts ware green- brown in color. However, after acting of FeNO3 within 20min, the suspension showed the change in color and turned dark brown after 4 hours of incubation at room temperature. Formation of Iron oxide nanoparticles was confirmed using X-ray is spectral analysis and showed the characteristic Bragg peaks of (111) to green tea extract and (111) to celery extract, plant of the face center cubic (FCC) Iron Oxide nanoparticles. The scanning electron microscope (SEM) Iron oxide nanoparticles see small particles and rode. The synthesized Fe2O3 NPs colloidal solution has shown better antibacterial activity against both Gram-positive and Gram-negative bacterial strains. The diameters of the inhibition zones of Fe2O3 NPs against the bacterial strains were, S. aureus (27 mm) p. aerugino (29mm) with camellia sinensis extract and S. aureus (22 mm) p. aerugino (25mm) with Apium graveolens exiract at 50 μg/ml concentration.
Synthesis, Iron Oxide Nanoparticles, Camellia Sinensis Leaves (Green Tea), Apium Graveolens (Celery), Extract, Antibacterial Activity
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Wisam Jafer Aziz, Aliyaa Abd Urabe, Chemical Preparation of Iron Oxide Nanoparticles Using Plants Extracts in Antibacterial Application, International Journal of Bioorganic Chemistry. Vol. 4, No. 1, 2019, pp. 1-6. doi: 10.11648/j.ijbc.20190401.11
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Abou El-Nour KMM, Eftaiha Aa, Al-Warthan A, Ammar RAA. Synthesis and applications of silver nanoparticles. Arabian Journal of Chemistry. 2010; 3 (3): 135-40.
Mohanpuria P, Rana NK, Yadav SK. Biosynthesis of nanoparticles: technological concepts and future applications. Journal of Nanoparticle Research. 2007; 10 (3): 507-17.
Padil V. V. T. and Černík M. (2013). Green synthesis of copper oxide nanoparticles using gum karaya as a biotemplate and their antibacterial application. Int. J. Nanomed., 8, 889-898.
Hoseyni S. J., Manoochehri M. and Asli M. D. Synthesis of cobalt nanoparticles by complex demolition. method using the reaction between organic ligand Schiff base and cobalt chloride by ultrasonication. Bulletin de la Société Royale des Sciences de Liège, (2017). 86, 325-331.
Koyyati R., Kudle K. R. and Padigya P. R. M. Evaluation of antibacterial and cytotoxic activity of green synthesized cobalt nanoparticles using Raphanus sativus var. longipinnatus leaf extract. Int. J. PharmTech Res (2016 (., 472-466 (3) 9.
A. Phukan, R. P. Bhattacharjee, D. K. Dutta, Stabilization of SnO2 nanoparticles into the nanopores of modified Montmorillonite and their antibacterial activity, Adv. Powder Technol. 28 (1) (2017) 139–145.
C. Ragupathi, L. John, Kennedy, J. Judith Vijaya, A new approach: Synthesis, characterization and optical studies of nano-zinc aluminate, Adv. Powder Technol. 25 (2014) 267–273.
A. B. Samui, D. S. Patil, C. D. Prasad, N. M. Gokhale, Synthesis of nanocrystalline 8YSZ powder for sintering SOFC material using green solvents and dendrimer route, Adv. Powder Technol. 27 (5) (2016) 1879–1884.
M. Sundrarajan, S. Ambika, K. Bharathi, Plant-extract mediated synthesis of ZnO nanoparticles using Pongamia pinnata and their activity against pathogenic bacteria, Adv. Powder Technol. 26 (2015) 1294–1299.
P. Raveendran, J. Fu, S. L. Wallen, Completely ‘‘green” synthesis and stabilization of metal nanoparticles, J. Am. Chem. Soc. 125 (2003) 13940–13941.
R. S. Patil, M. R. Kokate, S. S. Kolekar, Bioinspired synthesis of highly stabilized silver nanoparticles using Ocimum tenuiflorum leaf extract and their antibacterial activity, Spectrochim. Acta A Mol. Biomol. Spectrosc. 91 (2012) 234–238.
M. Fazlzadeh, K. Rahmani, A. Zarei, H. Abdoallahzadeh, F. Nasiri, R. Khosravi, A novel green synthesis of zero valent iron nanoparticles (NZVI) using three plant extracts and their efficient application for removal of Cr (VI) from aqueous solutions, Adv. Powder Technol. 28 (2017) 122–130.
J. K. Patra, Y. Kwon, K. -H. Baek, Green biosynthesis of gold nanoparticles by onion peel extract: Synthesis, characterization and biological activities, Adv. Powder Technol. 27 (2016) 2204–2213.
A. Phukan, R. P. Bhattacharjee, D. K. Dutta, Stabilization of SnO2 nanoparticles into the nanopores of modified Montmorillonite and their antibacterial activity, Adv. Powder Technol. 28 (2017) 139–145.
B. Siripireddy, B. K. Mandal, Facile green synthesis of zinc oxide nanoparticles by Eucalyptus globulus and their photocatalytic and antioxidant activity, Adv. Powder Technol. 28 (2017) 785–797.
Wisam J. Aziz and Haneen A. Jassim, A NEW PARADIGM SHIFT TO PREPARE COPPER NANOPARTICLES USING BIOLOGICAL SYNTHESIS AND EVALUATION OF ANTIMICROBIAL ACTIVITY, Plant Archives Vol. 18 No. 2, 2018 pp. 2020-2024 e- ISSN: 2581-6063 (online), ISSN: 0972-5210.
S. F. Hasany, I. Ahmed, Rajan J, A. Rehman, Systematic Review of the Preparation Techniques of Iron Oxide Magnetic Nanoparticles, Nanoscience and Nanotechnology 2012, 2 (6): 148-158, DOI: 10. 5923/j. nn. 20120206. 01, (2012).
Olanrewaju Sam Olayeriju, Mary Tolulope Olaleye, Olamide Olajusi Crown, Kayode Komolafe, Aline Augusti Boligon, Margareth Linde Athayde and Akintunde Afolabi Akindahunsi, Ethylacetate extract of red onion (Allium cepa L.) tunic affects hemodynamic parameters in rats, Food Science and Human Wellness 4 -115–122 (2015).
Wei Wu Æ Quanguo He Æ Changzhong Jiang, Magnetic Iron Oxide Nanoparticles: Synthesis and Surface Functionalization Strategies, Nanoscale Res Lett 3: 397–415, DOI 10. 1007/s11671-008-9174-9. 314 (2006) 964-967 (2008).
Ngo Ngoc Trung, Nguyen Thi Tho, Bui Thi Thuy Dung, Hoang Thi My Nhung, Nguyen Dinh Thang, Effects of ricin extracted from seeds of the castor bean (ricinu communis) on cytotoxicity and tumorigenesis of melanoma cells, Biomedical Research and Therapy, 3 (5): 633-644, DOI 10. 7603/s40730-016-0023-7, ISSN 2198-4093, (2016).
A. A. Haleemkhan, Naseem, B. Vidya Vardhini, Synthesis of Nanoparticles from Plant Extracts, International Journal of Modern Chemistry and Applied Science 2015, 2 (3), 195-203.
S. Kanagasubbulakshmi and K. Kadirvelu, Green Synthesis of Iron Oxide Nanoparticles using Lagenaria Siceraria and Evaluation of its Antimicrobial Activity, Defence Life Science Journal, Vol. 2, No. 4, October 2017, pp. 422-427, DOI: 10. 14429/dlsj. 2. 12277. 2017, DESIDOC.
Mandeep Kaur and Dimple Sethi Chopra, Green Synthesis of Iron Nanoparticles for Biomedical Applications, Glob J Nanomed, Review Article, Volume 4 Issue 4 - October 2018, DOI: 10. 19080/GJN. 2018. 04. 555643.
Valentin V. Makarov, Svetlana S. Makarova, Andrew J. Love, Olga V. Sinitsyna, Anna O. Dudnik, Igor V. Yaminsky, Michael E. Taliansky, and Natalia O. Kalinina, Biosynthesis of Stable Iron Oxide Nanoparticles in Aqueous Extracts of Hordeum vulgare and Rumex acetosa Plants, Langmuir, dx. doi. org/10. 1021/la5011924, Received: March 28, (2014).
Vinicius Ramos, Dejane Alves, Mariana Braga, Geraldo Carvalho, and Custódio Santos, Extraction and isolation of anti-tryptic castor-bean (Ricinus communis L.) substances and their effects on Spodoptera frugiperda (Smith, 1797) (Lepidoptera: Noctuidae), 128 CHILEAN JOURNAL OF AGRICULTURAL RESEARCH 73 (2) APRIL-JUNE 2013 Extraction and isolation of anti-tryptic castor-bean (Ricinus communis L.) substances.
Siska Siska, Abdul Mun‘im, Anton Bahtiar and Franciscus D. Suyatna, Effect of Apium graveolens Extract Administration on the Pharmacokinetics of Captopril in the Plasma of Rats, Sci. Pharm, doi: 10. 3390/scipharm86010006, 2018, 86, 6.
Mona. H. Ibrahim, A. A. Ibrahiem and T. R. Dallou, BIOSYNTHESIS OF SILVER NANOPARTICLES USING POMEGRANATE JUICE EXTRACT AND ITS ANTIBACTERIAL ACTIVITY, International Journal of Applied Sciencas and Biotechnology (IJASBT), (2016) Int J Appl Sci Biotechnol, Vol 4 (3): 254-258.
Alaa Alhazmi, Pseudomonas aeruginosa – Pathogenesis and Pathogenic Mechanisms, International Journal of Biology; Vol. 7, No. 2; 2015, ISSN 1916-9671 E-ISSN 1916-968X Published by Canadian Center of Science and Education.
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