Thermoprotective Properties of the Venom of the Transcaucasian Vipera (Macrovipera Lebetina Obtusa Dyigubsky, 1832)
International Journal of Ecotoxicology and Ecobiology
Volume 2, Issue 3, September 2017, Pages: 98-101
Received: May 15, 2017;
Accepted: Jun. 20, 2017;
Published: Jul. 21, 2017
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Topchiyeva Shafiga, National Academy of Sciences of Azerbaijan, Baku, Azerbaijan
Babaev Elmar, National Academy of Sciences of Azerbaijan, Baku, Azerbaijan
The paper presents data on the study of the thermoprotective properties of the venom of the Transcaucasian Vipeta (Macrovipera lebetina obtuse) on 120 white mongrel mice subjected to thermal exposure (30 - 50°C) for 30 minutes with the injection of zootoxin in doses (2 mg / kg and 4 mg / kg). It was found that the lifespan of mice was increased with respect to a series of experiments in which the injection of venoms under the conditions of normothermia was used for 28 - 30 minutes and 15 - 20 minutes to 120.0 ± 8.5 and 160.0 ± 19.7 minutes, respectively. It was found that in the posthyperthermic period after a 30-minute thermal exposure (30 - 50°C) in the control group of animal experiments, a 100% mortality was observed during 24 hours, and with the preliminary injection of a venom in the range of doses 2 - 4 mg / kg Survival in 30% - 50% of experimental animals was noted. Thus, the thermoprotective property of the venom of the Transcaucasian vipera has been proved.
Thermoprotective Properties of the Venom of the Transcaucasian Vipera (Macrovipera Lebetina Obtusa Dyigubsky, 1832), International Journal of Ecotoxicology and Ecobiology.
Vol. 2, No. 3,
2017, pp. 98-101.
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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