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Antimicrobial Activities of Four Strains of Streptomyces sp Isolated from the Pond of the Village of Demba Tiarki Tara in Mali
International Journal of Microbiology and Biotechnology
Volume 3, Issue 2, June 2018, Pages: 44-50
Received: Jun. 8, 2018; Accepted: Jul. 4, 2018; Published: Aug. 7, 2018
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Mamadou Wéléba Bagayoko, Department of Biology, Faculty of Science and Technology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali
Amadou Hamadoun Babana, Department of Biology, Faculty of Science and Technology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali
Adounigna Kassogué, Department of Biology, Faculty of Science and Technology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali
Doulaye Dembélé, Microarray and Sequencing Platform, Institute of Genetics and Molecular and Cellular Biology (IGBMC), University of Strasbourg, Illkirch, France
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The search for new molecules is needed to cope with the recrudescence of bacterial resistance. Actinomycetes, especially the genus Streptomyces remains the most requested for the production of bioactive substances. Nineteen samples of soil and mud from the pond of Demba Tiarki Tara were collected and treated. In total, 7 strains of Streptomyces were isolated by the calcium carbonate enrichment technique for the isolation of Streptomyces. The antimicrobial potency of isolated Streptomyces was assessed on human and plants pathogens (Staphylococcus aureus, Aspergillus flavus, Penicillium sp, Xanthomonas sp, Salmonella thyphi, Helminthos sp). Four of the tested actinmycetes strains showed antimicrobial activities against the pathogens used in the in vitro test. But only one strain showed high antagonist activity against Staphylococcus aureus and has a strong ability to produce melanin. Three strains were weakly active on Salmonella typhi. This result showed, for the first time, that the pond of Demba Tiarki Tara (DTT) contains bacteria producing bioactive compounds indicating the medical interest that the local population has in this pond. Secondary metabolite production by one strain may be an effective antibiotic for the management of resistant Staphylococcus aureus strains.
Antimicrobial Activities, Streptomyces, Pond
To cite this article
Mamadou Wéléba Bagayoko, Amadou Hamadoun Babana, Adounigna Kassogué, Doulaye Dembélé, Antimicrobial Activities of Four Strains of Streptomyces sp Isolated from the Pond of the Village of Demba Tiarki Tara in Mali, International Journal of Microbiology and Biotechnology. Vol. 3, No. 2, 2018, pp. 44-50. doi: 10.11648/j.ijmb.20180302.13
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