Mathematical Modeling of the Transmission Dynamics of Syphilis Disease Using Differential Transformation Method
Mathematical Modelling and Applications
Volume 5, Issue 2, June 2020, Pages: 47-54
Received: Feb. 21, 2020; Accepted: Mar. 9, 2020; Published: Mar. 24, 2020
Views 335      Downloads 181
Mbachu Hope Ifeyinwa, Department of Statistics, Imo State University, Owerri, Nigeria
Article Tools
Follow on us
In this work, we developed a mathematical model for the transmission dynamics of the Syphilis disease under some assumptions made. The method of differential transformation is employed to compute an approximation to the solution of the non-linear systems of differential equations for the transmission dynamic of the disease model. The differential transformation method is a semi-analytic numerical method or technique, which depends on Taylor series and has application in many areas including Biomathematics. The disease-free equilibrium of the syphilis model is analyzed for local asymptotic stability and the associated epidemic basic reproduction number R0 is less than unity. It is also known that the global dynamics of the disease are completely determined by the basic reproduction number. Sensitivity analysis is performed on the model’s parameters to investigate the most sensitive parameters in the dynamics of the disease, for control and eradication.
Syphilis Disease, Differential Transformation Method, Transmission Dynamics, Endemic Equillibrium, Mathematical Modeling
To cite this article
Mbachu Hope Ifeyinwa, Mathematical Modeling of the Transmission Dynamics of Syphilis Disease Using Differential Transformation Method, Mathematical Modelling and Applications. Vol. 5, No. 2, 2020, pp. 47-54. doi: 10.11648/
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Akinboro F. S., Alao S. and Akinpelu F. O. (2014) Numerical Solution of SIR Model using Differential Transformation Method and Variational Iteration Method. Vol. 22. Pg 82-92.
Aris S. and Ivey R. M. S. (2004) Principles of Mathematical Modeling; 1st Edition, Academic Press, New York.
Brauer F. and Castillo-Chavez C. (2001) Mathematical Models in Population Biology and Epidemiology the Amerian Mathematical Monthly 40: 267-291.
Dym C. L. and Ivey E. S. (2002) Principles of Mathematical Modeling, 1st Edition, Academic Press, New York.
Garnett G. P., Aral S. O., Hoyle D. V., Cates W. and Anderson R. M. (1997) The natural history of syphilis: implications for the transition dynamics and control of infection. Sex Transm Dis. Vol. IV. Pp 185-200.
Gumel A. B., Jean M. S., Oluwaseun S., Yibeltal A. T. (2017). Mathematics of a sex-structured model for syphilis transmission dynamics.
Iboi E. and Okuonghae D. (2016) Population Dynamics of a Mathematical model for syphilis. Appl Math Modeling, Vol. IV, Pp. 3573-3590.
Kermack, W. O and McKendrick, A. G (1927). A Contribution to the Mathematical Theory of Epidemics, Proceedings of the Royal Society Vol. 115, No. 772, pp. 700-721.
Kiarie J., Mishra C. K., Temmerman M. and Newman L. (2015) Accelerating the dual elimination of mother-to-child transmission of syphilis and HIV: why now?, International Journal of Gynecology Obstetrics; Vol. I, Pp. 130.
World Bank Life expectancy at birth; Accessed 12 May 2018.
World Health Report, the world health report 2004-changing history., Assessed June 28, 2018.
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
Tel: (001)347-983-5186