Risk Factors of Patent Ductus Arteriosus in Preterm
American Journal of Pediatrics
Volume 6, Issue 2, June 2020, Pages: 168-172
Received: Mar. 14, 2020; Accepted: Apr. 7, 2020; Published: Apr. 29, 2020
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Authors
Anak Agung Made Wijaya Kusuma, Department of Child Health, Udayana University Medical Faculty/Sanglah Hospital, Denpasar, Bali, Indonesia
Eka Gunawijaya, Department of Child Health, Udayana University Medical Faculty/Sanglah Hospital, Denpasar, Bali, Indonesia
I Gusti Ngurah Sanjaya Putra, Department of Child Health, Udayana University Medical Faculty/Sanglah Hospital, Denpasar, Bali, Indonesia
Ni Putu Veny Kartika Yantie, Department of Child Health, Udayana University Medical Faculty/Sanglah Hospital, Denpasar, Bali, Indonesia
I Made Kardana, Department of Child Health, Udayana University Medical Faculty/Sanglah Hospital, Denpasar, Bali, Indonesia
I Made Gede Dwi Lingga Utama, Department of Child Health, Udayana University Medical Faculty/Sanglah Hospital, Denpasar, Bali, Indonesia
I Wayan Gustawan, Department of Child Health, Udayana University Medical Faculty/Sanglah Hospital, Denpasar, Bali, Indonesia
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Abstract
Patent Ductus Arteriosus (PDA) is one of acyanotic congenital heart diseases that often occurs in preterm infants and closely related to an increased risk of complications for sufferers. Identification of PDA risk factors in preterm infants is very important, so that the diagnosis and management can be done earlier. In this study we aimed to determine risk factors of PDA in preterm infants. This case-control study was conducted between July 2017 and April 2018, analysed 43 preterm infants with PDA as the case group and 43 preterm infants without PDA as the control group. The basic information related to characteristics, risk of infection and perinatal history in both groups were collected. Bivariate and multivariate analysis with logistic regression were performed to identify risk factors for PDA. We found several factors were identified significantly (P<0.05) as risk factors for PDA including premature rupture of membranes >12 hours (OR 7.25; 95% CI: 2.08 - 25.09) and thrombocytopenia in the first 24 hours (OR 15.11; 95% CI: 3.73 - 61.13). This study concluded premature rupture of membranes >12 hours and thrombocytopenia in the first 24 hours were proven to increase the risk of PDA in preterm infants.
Keywords
Risk Factor, PDA, Preterm, Thrombocytopenia, Premature Rupture of Membranes
To cite this article
Anak Agung Made Wijaya Kusuma, Eka Gunawijaya, I Gusti Ngurah Sanjaya Putra, Ni Putu Veny Kartika Yantie, I Made Kardana, I Made Gede Dwi Lingga Utama, I Wayan Gustawan, Risk Factors of Patent Ductus Arteriosus in Preterm, American Journal of Pediatrics. Vol. 6, No. 2, 2020, pp. 168-172. doi: 10.11648/j.ajp.20200602.29
Copyright
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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