A Case of a Child with Stroke and Severe Hypertension Due to Vasculopathy in Neurofibromatosis Type I
American Journal of Pediatrics
Volume 3, Issue 1, January 2017, Pages: 1-3
Received: Sep. 14, 2016;
Accepted: Oct. 12, 2016;
Published: Mar. 17, 2017
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Kusa K., Department of Pediatrics, Faculty Hospital, Charles University in Hradec Králové, Hradec Králové, Czech Republic
Rozsival P., Department of Pediatrics, Faculty Hospital, Charles University in Hradec Králové, Hradec Králové, Czech Republic
Melek J., Department of Pediatrics, Faculty Hospital, Charles University in Hradec Králové, Hradec Králové, Czech Republic
Lukeš A., Pediatric Cardiology, Faculty Hospital, Charles University in Hradec Králové, Hradec Králové, Czech Republic
Štefáčková Š., Pediatric Neurology, Faculty Hospital, Charles University in Hradec Králové, Hradec Králové, Czech Republic
Albahri Z., Department of Pediatrics, Faculty Hospital, Charles University in Hradec Králové, Hradec Králové, Czech Republic
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Ischemic stroke is an infrequent disease of pediatric patients. We report a case of 2 year old child with neurofibromatosis, who had acute hemiplegia and severe hypertension (required artery angioplasty) due to both cerebral vascular disease and renal artery stenosis.
Neurofibromatosis, Vasculopathy, Stroke, Renovascular Stenosis
To cite this article
A Case of a Child with Stroke and Severe Hypertension Due to Vasculopathy in Neurofibromatosis Type I, American Journal of Pediatrics.
Vol. 3, No. 1,
2017, pp. 1-3.
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
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Lammert M, Friedman JM, Kluwe L, Mautner VF. Prevalence of neurofibromatosis 1 in German children at elementary school enrollment. Arch Dermatol 2005; 141: 71.
Friedman JM. Neurofibromatosis 1. GeneReviews® [Internet]. http://www.ncbi.nlm.nih.gov/books/NBK1109/.
Rea D, Brandsema JF, Armstrong D, et al. Cerebral arteriopathy in children with neurofibromatosis type 1. Pediatrics 2009; 124: e476.
Cairns AG, North KN. Cerebrovascular dysplasia in neurofibromatosis type 1. J Neurol Neurosurg Psychiatry 2008; 79: 1165.
McNiece KL, Poffenbarger TS, Turner JL, Franco KD, Sorof JM, et al. Prevalence of hypertension and pre-hypertension among adolescents. J Pediatr 2007; 150: 640-644.
Hiner LB, Falkner B. Renovascular hypertension in children. Pediatr Clin North Am. 1993; 40: 123-140.
Stanley JC, Criado E, Upchurch Jr GR, Brophy PD, Cho KJ, Rectenwald JE. Pediatric renovascular hypertension: 132 primary and 30 secondary operations in 97 children. J Vasc Surg. 2006; 44: 1219-1229.
Boulanger JM1, Larbrisseau A. Neurofibromatosis type 1 in a pediatric population: Ste-Justine's experience. Can J Neurol Sci. 2005; 32 (2): 225-231.
Tekin M, Bodurtha JN, Riccardi VM. Cafe au lait spots: the pediatrician's perspective. Pediatr Rev. 2001; 22 (3): 82-90.
Albahri Z, Lukeš A And Rozsíval P. Peripheral facial paralysis in an infant with malignant hypertension and suspected neurofibromatosis disease. Journal of the Neurological Science. 2015; (357): 1: 172–e173.
Malav IC, Kothari SS. Renal artery stenosis due to neurofibromatosis. Ann Pediatr Cardioly. 2009; 2: 167-169.
A. E. Lin, P. Birch, B. R. Korf, R. Tenconi, M. Niimura, M. Poyhonen, et al. Cardiovascular malformations and other cardiovascular abnormalities in Neurofibromatosis type I. Am J Med Genet. 2000; 95: 108-117.
Friedman J. M., J. Arbiser, J. A. Epstein, D. H. Gutman, Sj Huot, A. E. Lin, et al. Cardiovascular disease in neurofibromatosis 1: report of the NF1 cardiovascular task force Genet Med 2002; 4: 105-111.
Konig K, Gellermann J, Querfeld U, Schneider MB. Treatment of severe renal artery stenosis by percutaneous transluminal renal angioplasty and stent implantation: review of the pediatric experience: apropos of two cases. Pediatr Nephrol. 2006; 21: 663-671.
Meyers KE1, Cahill AM, Sethna C. Interventions for pediatric renovascular hypertension. Curr Hypertens Rep. 2014; 16 (4): 422.