Breastfeeding in Mother to Child Transmission in HIV Patient in West Java
American Journal of Pediatrics
Volume 2, Issue 4, July 2016, Pages: 15-18
Received: Jul. 1, 2016;
Accepted: Nov. 5, 2016;
Published: Dec. 10, 2016
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Anggraini Alam, Department of Pediatrics-Hasan Sadikin General Hospital, Universitas Padjadjaran, Bandung, West Java, Indonesia
Riyadi Riyadi, Department of Pediatrics-Hasan Sadikin General Hospital, Universitas Padjadjaran, Bandung, West Java, Indonesia
Filla Reviyani Suryaningrat, Department of Pediatrics-Hasan Sadikin General Hospital, Universitas Padjadjaran, Bandung, West Java, Indonesia
Yanti Siauta, Department of Pediatrics-Hasan Sadikin General Hospital, Universitas Padjadjaran, Bandung, West Java, Indonesia
Yelliantty Yelliantty, Department of Food Technology, Pasundan University, Bandung, Indonesia
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Estimates and projections of children living with HIV, the number of new HIV infections and AIDS-related deaths show an increasing trend every year. The number of children living with HIV is projected increase from 20,181 in 2014 to 31,146 in 2019, and the projected number of new infections in this age will increase from 4,653 in 2014 to 5,309 in 2019. On the other hand, the estimated number and projections of AIDS-associated deaths in children will change from 2,107 in 2014 to 2,950 in 2019. The objective of this study is to identify one of risk factor in HIV transmission from mother to child, which is breastfeeding and enrich the knowledge related to risk factors of HIV transmission from mother to child, so that the transmission rate can be reduce. This study was a case-control design conducted in the Hasan Sadikin General Hospital, Bandung. From 2002 until 2010. Subjects were all children, from 6-14 years old which are carried out the HIV test. Two groups were observed. First group were children with HIV positive and control group were HIV negative children with HIV positive mother. Data on breastfeeding history was obtained from interviews with family. The whole pregnant and lactating women have not been taking ART. One hundred and twenty-eight children were included in the analysis. There was more male (59%) than female children (41%). There were 68 HIV positive children in the case group and 60 children in the control group. Main delivery method in both case and control group was vaginal birth (75% and 52%). Breastfeeding was much higher in case group (88% vs 52%). Association between HIV infection in children and delivery method is not significant. On the other hand, breastfeeding is significantly associated with HIV infection in children. Children who were breastfed are twelve times (95% CI 3.275 – 62.981) more likely to have HIV infection. It was concluded that breastfeeding is an important risk factor in HIV transmission from mother to child, when mothers had had no ARV therapy.
Breastfeeding, HIV, Transmission
To cite this article
Filla Reviyani Suryaningrat,
Breastfeeding in Mother to Child Transmission in HIV Patient in West Java, American Journal of Pediatrics.
Vol. 2, No. 4,
2016, pp. 15-18.
Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Pedoman Pencegahan Penularan HIV dari Ibu ke Anak. Kementerian Kesehatan Republik Indonesia.. Available from: http:// www. depkes.com.
Rencana Aksi Nasional Pencegahan Penularan HIV dari Ibu ke Anak (PPIA) Indonesia 2013-2017. KesehatanRepublik Indonesia. Available from: http:// www.depkes.com.
Guidelines for second generation HIV surveillance: an update: Know your epidemic. Joint United Nations Programme on HIV/ AIDS. World Health Organization. Available from http:// www.who.int.
Situasi HIV/AIDS di Indonesia Tahun 1987-2006. Pusat Data dan Informasi, Departemen Kesehatan R. I. Jakarta, 2006. Available from: http:// www.depkes.com.
Fauci A, Braunwald E, et.al. Human Immunodeficiency Virus Disease. In: Harrison’s Principles of Internal Medicine. 17th Edition. United States of America. McGraw-Hill Companies 2008. p. 1-10.
Cunningham FG, Gant NF, Lereno KJ, Gilstrap III LC, Hanth JC, Wenstrom KD. Human Immunodeficiency Virus Infection. In: William’s Obstetric. 22nd Edition. New York: Mc Graw-Hill; 2001. p. 1-8.
Djoerban Z, Djauzi S. HIV/AIDS di Indonesia. Dalam: Buku Ajar Ilmu Penyakit Dalam. Jilid 3. Edisi 4. Jakarta: Interna Publishing. 2006. Hal.1803-7.
Decherney A, Goodwin M. et.al. Human Immunodeficiency Virus Infection. In: Current Diagnosis and Treatment Obstetrics and Gynecology. 10th Edition. United States of America. McGraw-Hill Companies 2007. p. 1-6.
Panduan Tatalaksana Klinis Infeksi HIV pada Orang Dewasa dan Remaja, Edisi Kedua. Departemen Kesehatan R. I. 2007. Available from: http:// www.depkes.com.
HIV classification: CDC and WHO Staging System. HRSA HIV/AIDS Bureau. June 2012. World Health Organization. Available from http:// www. who.int.
Bulterys, M., Ellington S., Kourtis AP. HIV-1 and Breastfeeding: Biology of Transmission and Advances in Prevention. Clin Perinatol 37 (2010) 807–824.
Depkes RI. Pedoman Nasional Pencegahan Penularan HIV dari Ibu ke Bayi, 2006.
WHO. Antiretroviral drug for treating pregnant women and preventing HIV infection in infant in resource – limited setting. HIV/AIDS Programme. Recommendation for a public health approach, 2006 version. Diambil dari: http://www.who.int/hiv/pub/guidelines/pmtctguidelines2.pdf.
Depkes RI. Pedoman Nasional Perawatan, Dukungan dan Pengobatan bagi ODHA, 2003.
Alimonti J, Blake T, Fowke K. Mechanisme of CD4 T–lymphocyte cell death in HIV infection. Journal of General Virology 2003;22:1649-61.
Vertical transmission (cited 2011). www.unaids.org
Djauzi S, Doerban Z. Penatalaksanaan HIV/AIDS di pelayanan kesehatan dasar, Pokdiksus AIDS FKUI/RSCM dan Yayasan Pelita Ilmu, Jakarta, 2003.
Yunihastuti E, Wibowo N, Djauzi S, Djoerban Z. Infeksi HIV pada kehamilan, Fakultas Kedokteran Universitas Indonesia, Jakarta 2003.
Sherr L. Vertical transmission of HIV-pregnancy and infant issues. In: Rohleder P, editor. HIV/AIDS in South Africa 25 Years. Springer Science, New York; 2009: hal. 183-205.
WHO. Strategic approaches to the prevention of HIV infection in children. Report of a WHO meeting, Morges, Switzerland, 2002.
WHO. Infant feeding and HIV transmission. Department of Nutrition for Health and Development, 2005.