Analysis of Sputum Culture and Drug Sensitivity Test in Patients with Severe Pneumonia Who Have Abnormal Klebsiella Pneumoniae
European Journal of Clinical and Biomedical Sciences
Volume 6, Issue 2, April 2020, Pages: 22-25
Received: Apr. 20, 2020; Accepted: May 6, 2020; Published: May 19, 2020
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Yanru Luo, Department of Pharmacy, The First Affiliated Hospital of Jinan University, Guangzhou, China
Jufeng Li, Department of Pharmacy, The First Affiliated Hospital of Jinan University, Guangzhou, China
Xuwei Lin, ICU, Peking University Shenzhen Hospital, Shenzhen, China
Lingfeng Zeng, Department of Pharmacy, The First Affiliated Hospital of Jinan University, Guangzhou, China
Jieyi Zhou, Department of Pharmacy, The First Affiliated Hospital of Jinan University, Guangzhou, China
Zhidong Zhang, Department of Pharmacy, The First Affiliated Hospital of Jinan University, Guangzhou, China
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Objective: To analyze sputum culture and drug sensitivity test in patients with severe pneumonia who have abnormal Klebsiella pneumoniae. Methods: 216 patients who were diagnosed as severe pneumonia were invested to join our study. All participants received the sputum culture test before they receive the treatment, their inspection time was from January 2016 to December 2016. we use different antibiotic discs to test the drug resistance in test medium, it can test the effects of several major antibiotics on Klebsiella pneumoniae. Our research is focus on the information about Drug resistance for Klebsiella pneumoniae. The collection information includes patient characteristics, Klebsiella pneumoniae source medical department and drug resistance of different antibiotics for Klebsiella pneumoniae. Result: Most Klebsiella pneumoniae sample from ICU (29.6%), Respiratory ward (31.0%), Neurological ward (19.0%) and Cardiovascular ward (43.7%). The klebsiella pneumoniae sample of another source are less than 5% in our research result. Some antibiotics have good influence to Klebsiella pneumoniae, that include cefoperazone/sulbactam, Meropenem and Ciprofloxacin (8.9% & 10.9% & 12.9%). However, the result indicate the Aztreonam has strong drug resistance for Klebsiella pneumoniae, it has 66 out of 99 (66.66%) number of resistant. Conclusion: The cefoperazone/sulbactam, Meropenem and Ciprofloxacin have good influence to improve klebsiella pneumoniae situation on patients with severe pneumonia. Additionally, some medical departments have more patients who severe pneumonia caused by klebsiella pneumoniae, such as ICU, Respiratory ward, Neurological ward and Cardiovascular ward.
Drug Resistance, Sputum Culture, Severe Pneumonia
To cite this article
Yanru Luo, Jufeng Li, Xuwei Lin, Lingfeng Zeng, Jieyi Zhou, Zhidong Zhang, Analysis of Sputum Culture and Drug Sensitivity Test in Patients with Severe Pneumonia Who Have Abnormal Klebsiella Pneumoniae, European Journal of Clinical and Biomedical Sciences. Vol. 6, No. 2, 2020, pp. 22-25. doi: 10.11648/j.ejcbs.20200602.12
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