Infection by Helicobacter pylori in Nova Iguaçu City, Rio de Janeiro Province, Brazil
European Journal of Clinical and Biomedical Sciences
Volume 3, Issue 1, February 2017, Pages: 19-23
Received: Jan. 19, 2017; Accepted: Feb. 14, 2017; Published: Mar. 1, 2017
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Authors
Pedro Vinhaes Braga da Silva, Host-Pathogen Interaction Department, Medicine Academic of Souza Marques Medicine School – FTESM, Rio de Janeiro, Brazil
Victoria Luiza Pacini, Host-Pathogen Interaction Department, Medicine Academic of Souza Marques Medicine School – FTESM, Rio de Janeiro, Brazil
Antonio Neres Norberg, Host-Pathogen Interaction Department, Souza Marques Medicine School – FTESM, Rio de Janeiro, Brazil; Pathology Department, UNIABEU/PROBIN University Center, Belford Roxo, Brazil; Public Health Department, Manhuaçu Management Sciences School – FACIG, Manhuaçu, Brazil
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Abstract
Helicobacter pylori infection is an important factor in the development of gastric carcinogenesis, but only a fraction of infected patients will develop gastric cancer. The aim of this research is to investigate the prevalence of H. pylori infection among dyspeptic patients of Nova Iguaçu city, province of Rio de Janeiro, Brazil. The research design is observational, retrospective and cross-sectional. The universe consisted of 56 patients of both genders aged over 25 years. Between January 2015 and July 2016, fragments of the lesions suggestive of H. pylori infection were collected through digestive endoscopy. The biopsy specimens were analyzed in a pathological anatomy laboratory and the validation of the infection was confirmed by the morphotintorial characteristics of the bacteria and biological tests: arched Gram negative bacilli through anatomopathological examination and positive urease test. Among patients suspected of H. pylori infection, 12 (21.4%) were positive. The infection was confirmed in dyspeptic patients in the studied region. The prevalence is below the global values, where 50% of the population is a pathogenous carrier. There were no significant differences between infection and gender correlation. Positivity was higher in people between the ages of 41 and 50 years.
Keywords
Helicobacter pylori, Gastric Mucosa, Dyspepsia, Cancer
To cite this article
Pedro Vinhaes Braga da Silva, Victoria Luiza Pacini, Antonio Neres Norberg, Infection by Helicobacter pylori in Nova Iguaçu City, Rio de Janeiro Province, Brazil, European Journal of Clinical and Biomedical Sciences. Vol. 3, No. 1, 2017, pp. 19-23. doi: 10.11648/j.ejcbs.20170301.14
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Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
[1]
Rubin E, Gorstein F, Rubin R, Schwarting R, Strayer D. Rubin Patologia. Bases Clínicopatológicas da Medicina. Guanabara Koogan, Rio de Janeiro, 2006.
[2]
Kumar V, Abbas AK, Aster JC. Patologia. Bases Patológicas das Doenças. Elsevier, Rio de Janeiro, 2016.
[3]
Porth CM, Matfin G. Fisiopatologia. Guanabara Koogan, Rio de Janeiro, 2010.
[4]
Go MF, Crowe SH. Virulence and pathogenicity. Clinics of North America, W. B. Saunders, Philadelphia, 2000.
[5]
Del Valle J, Cohen H, Laine L, Scheiman JM. Acid peptic disorders. In: Yamada T, Alpers DH, Laine L, Owiang C, Powell DW (eds). Textbook of Gastroenterology, Philadelphia, 1999.
[6]
Murray PR, Rosenthal KS, Pfaller MA. Microbiologia Médica. Elsevier, Rio de Janeiro, 2014.
[7]
Everhart JE. Recent developments in epidemiology of Helicobacter pylori. Gastroenterol Clin North America 2000; 29: 559-578.
[8]
Coura JR. Dinâmica das Doenças Infecciosas e Parasitárias. Guanabara Koogan, Rio de Janeiro, 2013.
[9]
Moss SF, Legon S, Davies J, Calam J. Cytokine gene expression. In Helicobacter pylori associated antral gastritis. Gut, 1995; 35: 1567-1570.
[10]
McColl KEL, Murray LS, Gillen D. Randomized trial of endoscopy with non-invasive H. pylori testing alone in the management of dyspepsia. BMJ 2002; 324: 999-1002.
[11]
Wotherspoon AC, Hortiz-Hidalgo C, Falzon MR, Isaacson PG. Helicobacter pylori associated with gastritis and primart B. cell gastric lymphoma. Lancet 1991; 338: 1575-1576.
[12]
Coelho LG, Leon-Barúa R, Quiglev EM. Latin-American consensus conference on Helicobacter pylori infection. Am J Gastroenterol 2000; 95: 2688-2691.
[13]
Parkin DM, Bray F, Ferlay J, Pisani J. Global cancer and statistics. CA Cancer J Clin 2005; 55: 74-108.
[14]
Mueller LB, Fagundes RB, Moraes CC, Rampozzo A. Prevalência da infecção por Helicobacter pylori e das lesões precursoras do câncer gástrico em pacientes dispépticos. Arq Gastroenterol 2007; 44 (2): 93-98.
[15]
Guy DE, Lynette YL, Julie EB, Harry H, Nicholas JT. Association of Helicobacter pylori infection with gastric carcinoma: a meta-analysis. Am J Gastrenterol 1999; 94: 2372-2379.
[16]
Rodrigues MN, Queiroz DMM, Rodrigues MT, Rocha AMC, Luz CR, Braga LBC. Prevalence of Helicobacter pylori infecion in Fortaleza, northeastern Brazil. Rev Saúde Pública 2005; 39 (5): 847-849.
[17]
Bravo LE, Cortés A, Carrascal E, Jamarillo R, Abdon LSG, Bravo E et al. Helicobacter pylori: patologia y prevalencia en biopsias gástricas en Colombia. Comb Med 2003; 34: 124-131..
[18]
Fábio-Parada JL, Júlio-Linhares OO, Ana-Orantes FP, Guido-Andreatta AS, Andrea-Sandoval LM, Fernando-Gutierréz LM et al. Prevalencia de Helicobacter pylori en un grupo de pacientes pediatricos infectados por el virus de la inmunodeficiencia humana. Rev Ciencia Tecnol y Salud 2015; 2 (2): 135-139.
[19]
Rosa-Belmiro F. Infecção por Helicobacter pylori em populações de Angola [doctoral thesis]. Nova Medical School. http://hnd.handle.net/10362/15725.
[20]
Contreras OC, Quispe JM, Goñi HB, Mendoza AC, Calderón EG, Moscol MD et al. Prevalencia de Helicobacter pylori en pacientes sintomáticos de consulta externa de la Red Rebagliati (EsSalud), Lima, Peru, en el período 2010-2013. Rev Gastroenterol Peru 2016; 36 (1): 49-55.
[21]
Capote EG, Ramírez EC, Garcell HG. Infección por Helicobacter pylori en pacientes atendidos en consulta de gastroenterología. Rev Ciencias Médicas 2014; 18 (3): 453-462.
[22]
Leyva LM, Dalmau NB, Heal ST, Vasquez AA, Chang NVF. Infección por Helicobacter pylori en el municipio de Palma-Soriano durante el período 2008-2014. MEDSAN 2016; 20 (11): 2339-2344.
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