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Prevalence and Antibiotic Susceptibility Patterns of Methicillin Resistant Staphylococcus Aureus in Patients Attending the Laquintinie Hospital Douala, Cameroon
European Journal of Clinical and Biomedical Sciences
Volume 2, Issue 6, December 2016, Pages: 92-96
Received: Oct. 31, 2016; Accepted: Dec. 3, 2016; Published: Jan. 5, 2017
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Authors
Marie Ebob Agbortabot Bissong, Department of Biomedical Sciences, Faculty of Health Sciences, University of Bamenda, Bambili, Cameroon
Therese Wirgham, Department of Medical Laboratory Sciences, St. Louis University Institute of Health and Biomedical Sciences, Bamenda, Cameroon
Mbi Alice Enekegbe, Department of Medical Laboratory Sciences, St. Louis University Institute of Health and Biomedical Sciences, Bamenda, Cameroon
Peter Thelma Ngwa Niba, Department of Medical Laboratory Sciences, St. Louis University Institute of Health and Biomedical Sciences, Bamenda, Cameroon
Frank Eric Tatsing Foka, Department of Biological Sciences, Faculty of Agriculture, Science and Technology, North West University, Mafikeng, South Africa
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Abstract
Methicillin Resistant Staphylococcus aureus (MRSA) is a major health problem worldwide. Diseases caused by these microorganisms most often are difficult to treat consequently, present with severe outcomes. Despite the increase association of MRSA in most hospital acquired infections, surveillance systems to control the spread of these infections are lacking especially in the developing countries. The present study is part of a major study developed to trail the incidence of multidrug resistant pathogens in clinical settings using available resources, with the aim to gather relevant data for the management and control of nosocomial infections. The specific objective of the current study is therefore to determine the prevalence and antimicrobial susceptibility of MRSA isolates from one of the largest hospitals in the country. This was a hospital based cross sectional study involving 114 participants, conducted between March and June 2016. Various clinical specimens were inoculated on to blood agar and mannitol salt agar and incubated at 35-37°C aerobically for 18-24 hours for the isolation of S. aureus. Isolates were identified using the catalase and coagulase tests. Sensitivity testing was done using the Kirby Bauer disk diffusion method. Data were analysed using SPSS version 20.0. Out of 114 samples analysed, S. aureus was isolated from 33 (28.95%) while MRSA was detected in 15 (13.16%). Antimicrobial susceptibility testing revealed high resistance (80-100%) to penicillins and no resistance to amikacin, lincomycin and ofloxacin. Multidrug resistance to at least three antibiotics was also observed among MRSA isolates. MRSA and multidrug resistant S. aureus are common in the study site. Therefore, there is a need for the improvement of surveillance systems to monitor and curb the spread of these resistant pathogens.
Keywords
Prevalence, Antimicrobial Resistance, Methicillin Resistant Staphylococcus Aureus, Laquintinie Hospital, Cameroon
To cite this article
Marie Ebob Agbortabot Bissong, Therese Wirgham, Mbi Alice Enekegbe, Peter Thelma Ngwa Niba, Frank Eric Tatsing Foka, Prevalence and Antibiotic Susceptibility Patterns of Methicillin Resistant Staphylococcus Aureus in Patients Attending the Laquintinie Hospital Douala, Cameroon, European Journal of Clinical and Biomedical Sciences. Vol. 2, No. 6, 2016, pp. 92-96. doi: 10.11648/j.ejcbs.20160206.16
Copyright
Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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