Physiochemical and Antibacterial Activity Investigation on Noble Schiff Base Cu(II) Complex
American Journal of Heterocyclic Chemistry
Volume 3, Issue 4, August 2017, Pages: 37-41
Received: Jul. 11, 2017; Accepted: Jul. 26, 2017; Published: Aug. 28, 2017
Views 1798      Downloads 152
Authors
Jasmin Ara Shampa, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh
Md. Rakibul Islam, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh
Md. Saddam Hossain, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh
Gagi Tauhidur Rahman, Department of Material Science & Engineering, University of Rajshahi, Rajshahi, Bangladesh
C. M. Zakaria, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh
Md. Kudrat-E-Zahan, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh
Article Tools
Follow on us
Abstract
Schiff base ligand and its Cu(II) complex had been synthesized by the condensation reaction of isatin with amino acids (cysteine / glycine / leucine / alanine ). The Structure and spectral properties of ligand and complex were confirmed by UV, FT-IR and some physiochemical measurements. The spectral properties showed that it was a distorted tetrahedral geometry with a tridentate ligand and chloride ion. IR spectral studies show the binding sites of the Schiff base ligand with the metal ion. Molar conductance data and magnetic susceptibility measurements give evidence for monomeric and non-electrolytic nature of the complexes. The Schiff base Cu(II) complex was subjected to antimicrobial studies screened by employing the Disc Diffusion method. All the synthesized complexes showed strong antibacterial activity.
Keywords
Transition Metal Cu(II) Complexes, Schiff Base, Amino Acid, Antimicrobial Studies
To cite this article
Jasmin Ara Shampa, Md. Rakibul Islam, Md. Saddam Hossain, Gagi Tauhidur Rahman, C. M. Zakaria, Md. Kudrat-E-Zahan, Physiochemical and Antibacterial Activity Investigation on Noble Schiff Base Cu(II) Complex, American Journal of Heterocyclic Chemistry. Vol. 3, No. 4, 2017, pp. 37-41. doi: 10.11648/j.ajhc.20170304.11
Copyright
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
[1]
Kirza, L. Ababel, N. Rau, N. Stanica. (2013) Synthesis and structural studies of complexes of Cu, Co, Ni and Zn with isonicotinic acid hydrazide and isonicotinic acid (1-naphthylmethylene) hydrazide J. Serb. Chem. Soc., 75 (2): 229-242.
[2]
L. Mitu, A. Kriza. (2007) Synthesis and Characterization of Complexes of Mn(II), Co(II), Ni(II) and Cu(II) with an Aroylhydrazone Ligand. Asian J. Chem. 19 (1): 658-664.
[3]
Saud I. Al-Resayesa, Mohammad Shakirb, AmbreenAbbasib, Kr. Mohammad Yusuf Aminc, Abdul Lateefc. (2007) Synthesis, spectroscopic, characterization and biological activities of N4O2 Schiff base ligand and its metal complexes of Co(II), Ni(II), Cu(II) and Zn(II). SpectrochimicaActa Part A. 93: 86-94.
[4]
K. D. Karlin, Z. Tyeklar, Ken. D. Karlin. Bioinorganic Chemistry of Copper. Chapman &Hall: NewYork. 1993.
[5]
V. Arun, N. Sridevi, P. P. Robinson, S. Manju, K. K. M. Yusuff. (2009) Ni(II) and Ru(II) Schiff base complexes as catalysts for the reduction of benzene. J. Mol. Catal. Chem., 304 (1): 191-198.
[6]
K. C. Gupta, A. K. Sutar. (2009) Catalytic activities of Schiff base transition metal complexes. Coord. Chem. Rev. 252 (12-14) 0: 1420-1450.
[7]
R. I. Kureshy, N. H. Khan, S. H. R. Abdi, S. T. Patel, P. Iyer. (1999) Synthesis, physico-chemical studies and solvent-dependent enantioselective epoxidation of 1, 2-dihydronaphthalene catalysed by chiral Ruthenium (II) Schiff base complexes. I. J. Mol. Cat. A Chem., 150 (1): 63-173.
[8]
Aly M. A. Hassaan. (1999) Nickel (II) chelates of Schiff bases derived from isatin and chromone with amino acids and substituted hydrazines. Transition Metal Chemistry, 15 (4): 283-285.
[9]
GagiTauhidur Rahman, A. B. M. Nazmul Islam, M. M. Haque, Md. Kudrat-E-Zahan, (2015) Investigation on Antimicrobial Activity of Newly Synthesized Mixed Ligand Ni(II) Ion Complexes. Int. J. Mat. Chem and Phys. 1 (2): 207-211.
[10]
Md. Kudrat-E-Zahan, Md. Abdul Alim Al-Bari, Md. Abul Bashar, Laila ArjumanBanu, M. M. Haque and M. Saidul Islam. (2015) Synthesis, Characterization and Biological Activity of Fe(III) Complexes with tartaric acid/succinic acid and heterocyclic amines. Int. J. Mat. Chem and Phys, 1 (1): 82-85.
[11]
M. M. Haque, Md. Kudrat-E-Zahan, Laila ArjumanBanu, Md. Shariful Islam and M. S. Islam. Synthesis and Characterization with Antineoplastic, Bio-Chemical, Cytotoxic and Antimicrobial studies of Schiff Base Cu(II) ion Complexes. Bioinorganic Chemistry and Applications. Volume 2015, Article ID 923087, 7 pages. http://dx.doi.org/10.1155/2015/923087
[12]
Md. Saddam hossain, Md. Ashraful Islam, C. M. Zakaria, Md. Kudrat-E-Zahan. (2016) Synthesis, Spectral and Thermal Characterization with Antimicrobial Studies on Mn(II), Fe(II), Co(II) and Sn(II) Complexes of Tridentate N, O Coordinating Novel Schiff Base Ligand. J. Chem. Bio, Phy. Sci. Sec. A. 6 (1): 041-051.
[13]
Md. Saddam Hossain, C. M. Zakaria, M. M. Haque, and Md. Kudrat-E- Zahan, (2016) Spectral and Thermal Characterization with Antimicrobial Activity on Cr(III) and Sn(II) Complexes containing N, O Donor Novel Schiff Base Ligand. International Journal of Chemical Studie, 4 (6): 08-11.
[14]
Md. Saddam Hossain, Shudeepta Sarker, A. S. M. Elias Shaheed, Md. Mamun Hossain, Abdul Alim-Al-Bari, Md. Rabiul Karim, C. M. Zakaria, Md. Kudrat-E-Zahan. (2017) Thermal and Spectral Characterization of Cr(III), Co(II) and Cd(II) Metal Complexes Containing Bis-Imine Novel Schiff Base Ligand Towards Potential Biological Application. Chemical and Biomolecular Engineering. 2 (1): 41-50.
[15]
Francis A. Carey. Organic chemistry. Seventh edition. The Mc Graw Hill companies, 2008: 539.
[16]
F. A. Cotton and G. Wilkinson. Advanced inorganic chemistry, fifth edition, Awiley-interscience publication. 1198: 768.
[17]
P. Deivanayagam, R. Pa. Bhoopathy, S. Thanikaikarasan. (2014) Synthesis, characterization, antimicrobial, analgesic and CNS studies of Schiff base Cu(II) complex derived from 4-choro-o-phenylene Diamine. Int. J. Adv. Chem. 2 (2): 166-170.
[18]
Md. Shiraj-U-Ddaula, Md. Anarul Islam, Shejuty aktar, Md. Khairul Islam, Md. Abdul Alim Al-Bari, Md. Masuqul Haque and Md. Kudrat-E-Zahan. Synthesis, Characterization and Antimicrobial Activity of Cd(II), Ni(II), Co(II) and Zr(IV) Metal Complexes of Schiff Base Ligand Derived from Diethylenetriamine and Isatin. Asian J. Research Chem. 7 (7): July 2014.
[19]
Bauer, A. W., D. M. Perry, and W. M. M. Kirby. (1999) Single disc antibiotic sensitivity testing of Staphylococci. A. M. A. Arch. Intern. Med. 104: 208–216.
ADDRESS
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
U.S.A.
Tel: (001)347-983-5186