Physiochemical and Antibacterial Activity Investigation on Noble Schiff Base Cu(II) Complex
American Journal of Heterocyclic Chemistry
Volume 3, Issue 4, August 2017, Pages: 37-41
Received: Jul. 11, 2017;
Accepted: Jul. 26, 2017;
Published: Aug. 28, 2017
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Jasmin Ara Shampa, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh
Md. Rakibul Islam, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh
Md. Saddam Hossain, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh
Gagi Tauhidur Rahman, Department of Material Science & Engineering, University of Rajshahi, Rajshahi, Bangladesh
C. M. Zakaria, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh
Md. Kudrat-E-Zahan, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh
Schiff base ligand and its Cu(II) complex had been synthesized by the condensation reaction of isatin with amino acids (cysteine / glycine / leucine / alanine ). The Structure and spectral properties of ligand and complex were confirmed by UV, FT-IR and some physiochemical measurements. The spectral properties showed that it was a distorted tetrahedral geometry with a tridentate ligand and chloride ion. IR spectral studies show the binding sites of the Schiff base ligand with the metal ion. Molar conductance data and magnetic susceptibility measurements give evidence for monomeric and non-electrolytic nature of the complexes. The Schiff base Cu(II) complex was subjected to antimicrobial studies screened by employing the Disc Diffusion method. All the synthesized complexes showed strong antibacterial activity.
Jasmin Ara Shampa,
Md. Rakibul Islam,
Md. Saddam Hossain,
Gagi Tauhidur Rahman,
C. M. Zakaria,
Physiochemical and Antibacterial Activity Investigation on Noble Schiff Base Cu(II) Complex, American Journal of Heterocyclic Chemistry.
Vol. 3, No. 4,
2017, pp. 37-41.
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