Case Series of Placental Mesenchymal Dysplasia with Live Birth
International Journal of Clinical and Experimental Medical Sciences
Volume 6, Issue 1, January 2020, Pages: 1-4
Received: Jun. 29, 2019; Accepted: Dec. 23, 2019; Published: Jan. 2, 2020
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Yanqing Kong, Department of Pathology, Shenzhen Maternity and Child Healthcare Hospital, Southern Medical University, Shenzhen, China
Yanrui Zhang, Department of Pathology, Shenzhen Maternity and Child Healthcare Hospital, Southern Medical University, Shenzhen, China
Hongping Tang, Department of Pathology, Shenzhen Maternity and Child Healthcare Hospital, Southern Medical University, Shenzhen, China
Xueyu Chen, Department of Neonatology, Shenzhen Maternity and Child Healthcare Hospital, Southern Medical University, Shenzhen, China
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Objective: Placental mesenchymal dysplasia (PDM) is a rare disease, the cause is unknown, some are called mesenchymal stem hyperplasia, and some are called pseudo-vesicular block or vascular malformation. The aim is to report the clinical and pathologic characteristics of three cases of placental mesenchymal dysplasia (PMD). Method: Pathologic and clinical data were retrieved from the electronic medical records. The data were reviewed and summarized by the same pathologist. Results: Maternal age was respective 36 years, 31 years and 33 years. Cesarean section was performed at 39 weeks, 37 weeks and 38 weeks, respectively. The newborns were born with birth weight of 1790, 2370 and 3150 grams, respectively, with placenta weight of 590, 579 and 510 grams respectively. Placenta for pathological examination was performed macroscopically thick-walled vessels. Microscopic observation showed that the part of the stem villus was saclikely dilated, the blood vessels were thickened in the villi, the blood vessel wall was thickened, the villus interstitial was loose, and the mucus was changed. Part of the villus edema and degeneration, no trophoblastic hyperplasia, the final villus structure is normal. Conclusion: The size of the lesions in the Placental mesenchymal dysplasia and the location of the lesion is closely related to the birth weight of the newborn. Detailed histology is necessary for diagnosis and differential diagnosis.
Placental Developmental Abnormality, Placental Disease, Vascular Disease, Hydatidiform Mole
To cite this article
Yanqing Kong, Yanrui Zhang, Hongping Tang, Xueyu Chen, Case Series of Placental Mesenchymal Dysplasia with Live Birth, International Journal of Clinical and Experimental Medical Sciences. Special Issue: Pathology. Vol. 6, No. 1, 2020, pp. 1-4. doi: 10.11648/j.ijcems.20200601.11
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This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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