Serodiagnosis of Hepatitis B Virus Infection among Jessu Community of Gombe State, Nigeria
International Journal of Infectious Diseases and Therapy
Volume 3, Issue 2, June 2018, Pages: 40-44
Received: Aug. 8, 2018;
Accepted: Aug. 24, 2018;
Published: Sep. 17, 2018
Views 1123 Downloads 94
Sheyin Zakka, Department of Medical Laboratory Science, University of Jos, Jos, Nigeria; School of Medicine and Allied Health Sciences, University of the Gambia, Banjul, Gambia
Frama Ishaku, Department of Medical Laboratory Science, University of Jos, Jos, Nigeria
Essien Unyime Cosmas, Department of Medical Laboratory Science, University of Jos, Jos, Nigeria
Shindang John, Department of Medical Laboratory Science, University of Jos, Jos, Nigeria
Bigwan Emmanuel Isa, Department of Medical Laboratory Science, University of Jos, Jos, Nigeria
Hepatitis B virus causes disease of the liver and is a global health problem that leads to liver cirrhosis and hepatocellular carcinoma. Despite the dangers posed by this silent and deadly disease, there is little or no documented work on Hepatitis B infections in Jessu community, Gombe State, North East Nigeria. This study was undertaken to determine the sero-prevalence of Hepatitis B Virus infection and possible risk factors associated with the transmission of HBV. Blood samples (3ml) were collected from 196 eligible consented subjects and the serum samples were tested for the presence of HBsAg using On Site HBsAg Rapid Test Kit manufactured by CTK Biotech, USA. The OnSite HBV 5-Parameter Rapid Test also manufactured by CTK Biotech, USA was used to confirm those that were positive. Of the 196 eligible subjects examined, 5.6% were confirmed positive for HBsAg, 8.6% were males and 2.9% were females. Age distribution of HBsAg among the population shows the highest seroprevalence of 8.9% HBsAg in ages 16-30 years, followed by 4.5% in ages 31-45 years while ages 0-15 years had 3.5% seroprevalence. Participants who share sharp objects recorded the highest prevalence of 6.3% HCV infection followed by blood transfusion with 5.9% prevalence and those with multiple sex partners had the least prevalence of 1.8% HCV infection. The seroprevalence of 5.6% HBV in this study indicated the presence of HBV in Jessu Community in Gombe State, North East Nigeria.
Essien Unyime Cosmas,
Bigwan Emmanuel Isa,
Serodiagnosis of Hepatitis B Virus Infection among Jessu Community of Gombe State, Nigeria, International Journal of Infectious Diseases and Therapy.
Vol. 3, No. 2,
2018, pp. 40-44.
TerwaseJM, and Chima K. Emeka.Prevalence of Hepatitis B Surface Antigen among Residents of Julius Berger Staff Quarters, Kubwa,Abuja. International Journal of Prevention and Treatment.2015; 4(2): 29-33.
Sarin S. K, M. Kumar, G. K. Lau, Z. Abbas, H. L. Y. Chan, C. J. Chen, D. S. Chen, H. L. Chen, P. J. Chen, R. N. Chien, A. K. Dokmeci, Ed Gane, J. L. Hou, W. Jafri, J. Jia, J. H. Kim, C. L. Lai, H. C. Lee, S. G. Lim, C. J. Liu, S. Locarnini, M. Al Mahtab, R. Mohamed, M. Omata,J. Park, T. Piratvisuth, B. C. Sharma, J. Sollano, F. S. Wang, L. Wei, M. F. Yuen, S. S. Zheng, and J. H. Kao. Asian-Paciﬁc clinical practice guidelines on the management of hepatitis B: update, Hepatology International. 2016; 10:1–98.
Okoye, Ikem Chris and Samba, ScholasticaAtteh.Sero-Epidemic Survey of Hepatitis B in a Population of Northern Nigeria.Animal Research International.2006;3(2): 485 – 488.
Adoga Moses P, Silas D. Gyar, Simon Pechulano, Obadiah D. Bashayi, Samuel E. Emiasegen, Timothy Zungwe, Odunayo H. Iperepolu, ChinweAgupugo, Simon M. Agwale. Hepatitis B virus infections in apparently healthy urban Nigerians: data from pre-vaccination tests, Journal of Infect Developing Countries. 2010;4(6):397-400.
Khan F., Shams S., Ihteshamud Din Qureshi ID., Israr M., Khan H.,Sarwar MT and Muhammad Ilya M. Hepatitis B virus infection among different sex and age groups in Pakistani. Virology Journal.2011; 8:225.
Geberemicheal A,Gelaw A, Moges F, D. M.Seroprevalence of hepatitis B virus infections among health care workers at the BulleHoraWoreda Governmental Health Institutions, Southern Oromia, Ethiopia. Journal Environ Occup Sciences. 2013; 2(1), 9–14.
Kennedy Okyere. Prevalence of Hepatitis B and C viral infections among children and adults presenting with hepatic disease at komfoanokye teaching hospital. http://hdl.handle.net/123456789/10109 2016; 1-21.
Geoffrey Zambezi Mutuma, Margaret W. Mbuchi, EberhardZeyhle, RanaFasana, Fredrick A. Okoth J. MainaKabanga, Kuria Julius, T., LusesoShiramba, M. KariukiNjenga, Peter. M. Kaiguri, Vincent Osidiana. Prevalence of Hepatitis B Virus (HBV) surface antigen and HBV- associated hepatocellular carcinoma in Kenyans of various ages, African Journal of Health Sciences. 2011;18 (1-2). 53-61.
WHO. Fact sheet on Hepatitis B, World Hepatitis day, July 28. 2015; 1.
Norah A. Terrault, Natalie H. Bzowej, Kyong-Mi Chang, Jessica P. Hwang, Maureen M. Jonas, and M. Hassan Murad.AASLD Practical Guidelines for Treatment of Chronic Hepatitis B. Official Journal of the American for the study of liver disease. 2011; 63 (1) 262 – 263.
WHO. Increase awareness and understanding of viral hepatitis. World hepatitis day, 28, July 2017; 1
Himont Bhattacharya, Debdutta Bhattacharya, S.R. Ghosal, Subarna Roy, & Sugunan A.P. Status of hepatitis B infection - a decade after hepatitis B vaccination of susceptible Nicobarese, an indigenous tribe of Andaman & Nicobar (A&N) islands with high hepatitis B endemicity, Indian Journal of Medicine Res. 2015; 141: 653-661.
Fuqiang Cui, LipinShen, Li LiHuaqing Wang, Fuzhen Wang, Shengli Bi, Jianhua Liu, Guomin Zhang, Feng Wang, HuiZheng, Xiaojin Sun, Ning Miao, Zundong Yin, ZijianFeng, Xiaofeng Liang, Yu Wang.Prevention of Chronic Hepatitis B after three Decades of Escalating Vaccination Policy, China; Emerging Infectious Diseases.2017; 23 (5). 765 – 767.
Thrusfield, M.V. Veterinary epidemiology. 3rd edn, UK, Blackwell Science. 2005; 178-179.
Ndako JA., Yahaya A., JosephineAmira JO., Debby T.Olaolu DT., Akande TA.Hepatitis B Virus (HBV) Infection among Alcoholic Consumers at a Local Community, North-East Nigeria.Journal of Natural Sciences Research.2013; 3(13): 2224-3186.
Obi, O.S; Baba, H.A; Baba, M.M; Amilo, G.I; Bukar, A. The effect of co-infection of HIV and Hepatotropic viruses on selected Biochemical and Haematological markers of patients in North-Eastern Nigeria. Intl journal of tropical diseases and health. 2014; 4(5): 568-581.
Isa MA.,Bello HS.,Gulani IA., Aliyu B. and Iliya H. Prevalence of Hepatitis B virus infection among children attending mohammedshuwa memorial hospital Maiduguri, Borno state, Nigeria; International Journal of Advanced Research in Biological Sciences. 2015; 2348-8069.
Wasa A. A and Maigana A. Prevalence of Hepatitis B Surface Antigen among Undergraduate Students of Gombe State University, Gombe.IOSR Journal of Pharmacy and Biological Science. 2013; 6 (6): 24-27.
Mustapha, S.K and Jibrin.The prevalenceof Hepatitis B surfaceantigemia in patients with HIV infection in Gombe, Nigeria.African Medical Journal. 2004; 4:10-11.
Okonko. IO.,Okerentugba PO. andAkinpelu AO. Prevalence of HBsAG among Attendees of ARFH Centre in Ibadan, Southwestern Nigeria; American-Eurasian Journal of Scientific Research. 2012; 7 (3): 100-105.
Mehment D., Melksah E., Sherif Y., GunayS., Tuner O., ZeryepS.Prevalence of Hepatitis B Infection in the Southeastern Region of Turkey, Comparison of Risk Factors for HBV Infection in Rural and Urban Areas.Journal Infectious Diseases.2005; 58:15-19.
Sule WF., I.O. Okonko IO., I.P. Yunusa IP., OduNN., N. Frank-Peterside N. Detection of Hepatitis B surface antigen and risk factors of transmission among HIV patients attending Universal Hospital Ankpa, Kogi State, Nigeria.Nature and Science. 2010; 9(10): 37-44.
Okechuckwu N., Godwin M., Egeudenia O., E. Desmond E., Patrick O. The Seroprevalence of Hepatitis B Viral Infection in HIV Tested Positive Individuals in Owerri, Imo State, Nigeria. Journal.Aids Clinical. Rec.2014; 5:273.
Adewole R. A, Omilabu S. A, Ayodele A. O. S, Gbotolorun O. M, and Anorue E.I. Prevalence of hepatitis B virus surface antigen (HBsAg) in patients attending dental centre of a tertiary hospital (a pilot study). Journal of Medicine and Medical Sciences 2013; 4(7): 275-279.
Edia-Asuke A.U., Abubakar Z., and Asuke S.Seroprevalence of Hepatitis B Infection among out-patieents Attending a Public Tertiary Institution in Kaduna State, Nigeria. Journal of Tropical Medicine and Surgery 2015; 3 (3):189-192.