Fiery Fevers - An Epidemiological Evaluation and Management Strategies Experience from a Community Based Day Care Centre
International Journal of Infectious Diseases and Therapy
Volume 5, Issue 1, March 2020, Pages: 17-22
Received: Dec. 25, 2019; Accepted: Mar. 5, 2020; Published: Mar. 24, 2020
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Authors
Hemalalitha Shilpa Renduchintala, Sri K Kishan Rao Hospital, Vanasthalipuram, Hyderabad, India
Kodamarthy Vamsi Mohan, Sri K Kishan Rao Hospital, Vanasthalipuram, Hyderabad, India
Sandhya Dixit, Sri K Kishan Rao Hospital, Vanasthalipuram, Hyderabad, India
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Abstract
Telangana has a long association with fiery fevers caused by mosquito bites. It is in fact in Telangana that Sir Ronald Ross discovered the malarial parasite in mosquito’s gut in the month of August 1897 for which he was later awarded Nobel Prize in 1902. Malaria has been high on the differential diagnosis in patients presenting with fever in this region. However, over the last two decades there has been an increased incidence of mosquito borne viral diseases with India becoming endemic for Dengue and Chikungunya. The prevalence of these has been on a rise and Telangana region has been no exception. An unpredictable and sudden outbreak of fever cases prevailed from August to October 2019 in Hyderabad, most of them were viral fevers and among them Dengue emerged as a major toll, to a lesser extent Chikungunya and others. Objective of this study is to present a clear and comprehensive picture of the prevailing causes of such a fever outbreak in this specified time frame in our Diagnostics and Day care centre. Serum samples were collected from all fever cases and sent to laboratory and analysed according to the following criteria –age, gender, presenting complaints, lab evaluation etc. The results have been interpretated in the form of tables, figures and graphs reflecting the predominant cause of fevers. The study showed that majority of the cases were in the age group 20–30 years with a male predilection and significant number of patients showed leucopenia and thrombocytopenia even in non dengue and non chikungungya patients. This sudden emergence is being attributed to sparkling vector transmission due to an incessant rainfall during this time inhabiting breeders in stagnant waters. It also reemphasizes the need for regular public health maintenance programmes including removing of stagnant water, mosquito control, regular public awareness camps. Need of the hour would be for both governmental and nongovernmental agencies to work in coordination to reduce the disease burden.
Keywords
Vectorborne Diseases, Dengue, Chikungunya, Leucopenia and Arthralgia
To cite this article
Hemalalitha Shilpa Renduchintala, Kodamarthy Vamsi Mohan, Sandhya Dixit, Fiery Fevers - An Epidemiological Evaluation and Management Strategies Experience from a Community Based Day Care Centre, International Journal of Infectious Diseases and Therapy. Special Issue: Infectious Diseases. Vol. 5, No. 1, 2020, pp. 17-22. doi: 10.11648/j.ijidt.20200501.14
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Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
[1]
Waggoner, J. J., et al. (2012), Viremia and Clinical Presentation in Nicaraguan Patients Infected With Zika Virus, Chikungunya Virus, and Dengue Virus. Clinical Infectious Diseases: 63 (12), 1584-1590.
[2]
Chakravarti A., Arora R., Luxemburger C (2012). Fifty years of dengue in India. Trans R Soc Trop Med Hyg: 106, 273-282.
[3]
Bhatt, S., et al.(2013). The global distribution and burden of dengue. Nature: 496 (7446), 504–507.
[4]
Shu PY, Huang JH (2004). Current advance in dengue diagnosis. Clin Diagn Lab Immunol: 11, 642-50.
[5]
Agarwal J, Kapoor G, Srivastava S, Singh KP, Kumar R, Jain A (2010). Unusual clinical profile of Dengue Infection in patients attending a tertiary care teaching hospital in north India. Int J Infect Dis: 14, 174-5.
[6]
Chaturvedi UC, Kapoor AK, Mathur A, Chandra D, Khan AM, Mehrotra RML (1970). A clinical and epidemiological study of an epidemic of febrile illness with haemorrhagic manifestations which occurred at Kanpur, India, in 1968. Bull World Health Organ: 43 (2), 281.
[7]
Chhina DK, Goyal O, Goyal P, Kumar R, Puri S, Chhina RS (2009). Haemorrhagic manifestations of dengue fever & their management in a tertiary care hospital in north India. Indian J Med Res: 129 (6), 718-721.
[8]
Duong, V., et al. (2015), Asymptomatic humans transmit dengue virus to mosquitoes. Proceedings of the National Academy of Sciences of the USA: 112 (47), 14688–14693.
[9]
G. N. Malavige, S. Fernando, D. J. Fernando, and S. L. Seneviratne (2004). “Dengue viral infections,” Postgraduate Medical Journal: 80 (948), 588–601.
[10]
Pandey N, Nagar R, Gupta S (2012). Trend of dengue virus infection at Lucknow, north India: a hospital based study. Indian J Med Res: 136 (5), 862.
[11]
World Health Organization. Dengue hemorrhagic fever: diagnosis, treatment and control. 1997.
[12]
World Health, O., Dengue: Guidelines for Diagnosis, Treatment, Prevention and Control. Dengue: Guidelines for Diagnosis, Treatment, Prevention and Control. 2009, Geneva: World Health Organization. 1-147.
[13]
Barniol J, Gaczkowski R, Barbato EV, da Cunha RV, Salgado D, Martı´nez E, et al (2011). Usefulness and applicability of the revised dengue case classification by disease: multi-centre study in 18 countries. BMC Infect Dis: 11, 106.
[14]
Dash PK, Sharma S, Srivastava A, Santhosh SR, Parida MM, Neeraja M, et al (2011). Emergence of dengue virus type 4 (genotype I) in India. Epidemiol Infect: 139 (06), 857–61.
[15]
Neeraja M, Iakshmi V, Teja VD, Lavanya V, Priyanka EN, Subhada K, et al (2014). Unusual and rare manifestations of dengue during a dengue outbreak in a tertiary care hospital in South India. Arch Virol: 159 (7), 1567–73.
[16]
Ganeshkumar P, Murhekar MV, Poornima V, Saravanakumar V, Sukumaran K, Anandaselvasankar A, et al. (2018). Dengue infection in India: A systematic review and metaanalysis. PLoS Negl Trop Dis: 12 (7): e0006618.
[17]
National Vectorborne Disease Control Program, Directorate General of Health Services. http://nvbdcp.gov.in/DENGU1.html.
[18]
Das S, Sarfraz A, Jaiswal N, Das P (2017). Impediments of reporting dengue cases in India. J Infect Public Health: 10, 494–498.
[19]
Kakkar M (2012). Dengue fever is massively under-reported in India, hampering our response. BMJ: 19 (354), e8574–e8574.
[20]
Murtola T, Vasan S, Puwar T, Govil D, Field R, Gong H, Bhavsar-Vyas A, Suaya J, Howard M, Shepard D, Kohli V, Prajapati P, Singh A, Mavalankar D (2010). Preliminary estimate of immediate cost of chikungunya and dengue to Gujarat, India. Dengue Bull: 34, 32–38.
[21]
Kumar D, Garg S. Economic burden of dengue fever on households in Hisar district of Haryana state, India (2014). Int J Adv Med Health Res: 1 (2), 99–103.
[22]
Garg P, Nagpal J, Khairnar P, Seneviratne SL (2008). Economic burden of dengue infections in India. Trans R Soc Trop Med Hyg: 102 (6), 570–7.
[23]
Shepard DS, Halasa YA, Tyagi BK, Adhish SV, Nandan D, Karthiga KS, Chellaswamy V, Gaba M, Arora NK, INCLEN Study Group (2014). Economic and disease burden of dengue illness in India. Am Soc Trop Med & Hygiene: 91 (6), 1235–42.
[24]
Duthade MM, Damle AS, Bhakre JB, Gaikwad AA, Iravane JA, Jadhav A, et al (2015). The Study of Detection of Dengue NS1 Antigen and IgM Antibody by ELISA in and around Aurangabad, India. Int J Curr Microbiol App Sci: 4 (10), 416-422.
[25]
Gopal KA, Kalaivani V, Anandan H (2016). Prevalence of Dengue Fever and Comparative Analysis of IgM and IgG Antibodies in Dengue Fever in Thoothukudi-Southern Coastal City, Tamil Nadu. Annals of International Medical and Dental Research: 2 (6), 4-7.
[26]
Hadinegoro SR, Arredondo-GarcõÂa JL, Capeding MR, Deseda C, Chotpitayasunondh T, Dietze R, et al (2015). Efficacy and Long-Term Safety of a Dengue Vaccine in Regions of Endemic Disease. N Engl J Med: 373, 1195-206.
[27]
Villar L, Dayan GH, Arredondo-Garcia JL, Rivera DM, Cunha R, Deseda C, et al (2015). Efficacy of a tetravalent dengue vaccine in children in Latin America. N Engl J Med: 372, 113-23.
[28]
WHO (2016). Dengue vaccine: WHO position. Wkly Epidemiol Rec: 91, 349-64.
[29]
WHO (2017). Updated Questions and Answers related to the dengue vaccine Dengvaxiaanditsuse. http://www.who.int/immunization/diseases/dengue/q_and_a_dengue_vaccine_dengvaxia_use/en/.
[30]
WHO (2018). Revised SAGE recommendation on use of dengue vaccine. http://www.who.int/immunization/diseases/dengue/revised_SAGE_recommendations_dengue_vaccines_apr2018/en/.
[31]
Garg S, Chakravarti A, Singh R, Masthi NRR, Goyal RC, Jammy GR, et al (2017). Dengue serotype-specific seroprevalence among 5- to 10-year-old children in India: a community-based cross-sectional study. Int J Infect Dis: 54, 25–30.
[32]
Bandyopadhyay B, Bhattacharyya I, Adhikary S, Konar J, Dawar N, Sarkar J, et al (2012). A comprehensive study on the 2012 dengue fever outbreak in Kolkata, India. ISRN Virol: 2013, 5.
[33]
E. Gupta, L. Dar, G. Kapoor, and S. Broor (2006), “The changing epidemiology of dengue in Delhi, India,” Virology Journal: 3, 92.
[34]
Balasubramaniam SM, Krishnakumar J, Stephen T, Gaur R, Appavoo NC (2011). Prevalence of Chikungunya in urban field practice area of a private medical college, Chennai. Indian J Community Med: 36, 124–7.
[35]
Selvavinayagam TS (2007). Chikungunya fever outbreak in Vellore, south India. Indian J of Community Medicine: 32 (4), 286–7.
[36]
Barde PV, Shukla MK, Bharti PK, Kori BK, Jatav JK, Singh N (2014). Co-circulation of dengue virus serotypes with chikungunya virus in Madhya Pradesh, central India. WHO South-East Asia Journal of Public Health: 3 (1), 36.
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