Endocrine Disruptor Compounds (EDC) Effects on Reproduction
International Journal of Diabetes and Endocrinology
Volume 3, Issue 1, March 2018, Pages: 18-22
Received: Mar. 25, 2018; Accepted: Apr. 12, 2018; Published: May 14, 2018
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Author
Thi Mong Diep Nguyen, Faculty of Biology-Agricultural Engineering, Quy Nhon University, Quy Nhon, Viet Nam
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Abstract
A large number of industrial chemical products (paints, flame retardants, pharmaceuticals, pesticides) are suspected or proved to act as endocrine disruptor compounds (EDCs). In the present survey of the literature, the main issue is to consider how to classify individual products as EDC or not. In this perspective, the different mechanisms leading to endocrine disruption are described: either by direct interaction with hormone receptors leading to its stimulation or inhibition, or by effect on endogenous hormone concentration through stimulation or inhibition of its synthesis or its degradation, or its binding to transport binding proteins. The present review takes particularly in consideration the effects of EDCs on the endocrine control of Reproduction in human and animals. Indeed, a number of EDCs can act as anti-androgens, anti-estrogens, and steroidogenic enzyme inhibitors that interfere with steroid action or production and thus can alter reproductive health.
Keywords
Endocrine Disruption, Endogenous Hormone, Reproduction, Reproductive Health
To cite this article
Thi Mong Diep Nguyen, Endocrine Disruptor Compounds (EDC) Effects on Reproduction, International Journal of Diabetes and Endocrinology. Vol. 3, No. 1, 2018, pp. 18-22. doi: 10.11648/j.ijde.20180301.14
Copyright
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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