International Journal of Clinical Oncology and Cancer Research
Volume 5, Issue 2, June 2020, Pages: 16-23
Received: Mar. 21, 2020;
Accepted: Apr. 10, 2020;
Published: May 15, 2020
Views 351 Downloads 116
Hong Weixi, Nursing, First Clinical Medical College, Jinan University, Guangzhou, China
Wang Yu, Infections Department, The First Affiliated Hospital of Jinan University, Guangzhou, China
Wang Xiaolan, Hepatological Surgery Department, The First Affiliated Hospital of Jinan University, Guangzhou, China
Zuo Feifei, Nursing, First Clinical Medical College, Jinan University, Guangzhou, China
Lin Jing, Nursing, First Clinical Medical College, Jinan University, Guangzhou, China
Background HCC patients suffering from various symptoms during palliative care. Effective symptom management can reduce patient's painful symptom experience and improve their quality of life. The researches on symptom management have shifted from single symptom to multiple symptoms occurring simultaneously. Meanwhile, different studies varied considerably on the symptom clusters and its composition. Objectives The aim of this systematic review was to summarize the compositions, measures, and analytical techniques of symptom clusters in patients with HCC. Method We conducted a comprehensive search to identify published studies about symptom clusters in patients with HCC. Databases including National Knowledge Infrastructure (CNKI), Chinese Science and Technology Journal Database (VIP), Wanfang Technology Journal full-text database, PubMed, EMbase and Web of Science and the studies included is from January 1, 2001 to November 24, 2019. Results There are seven articles compliance with inclusion criteria. Four symptom clusters were most commonly reported: Cluster 1: nausea/vomiting; Cluster 2: pain/fatigue/sleep disturbance/dry mouth/lack of appetite/change in taste; Cluster 3: sadness/distress/nervous; Cluster 4: jaundice/abdominal distension/itching/diarrhea/constipation. Conclusion This systematic review summarized the statistical methods, assessment tools, symptom clusterand composition of 7 included studies. Due to the lack of consensus on the definition of symptom cluster, the differences of statistical methods, assessment tools, sample characteristics and measuring time, the conclusion of the symptom cluster of HCC patients varied considerably in combinations.
Symptom Clusters in Patients with HCC: A Systematic Review, International Journal of Clinical Oncology and Cancer Research.
Vol. 5, No. 2,
2020, pp. 16-23.
Lissi Hansen. Symptom Distress in Patients with Advanced Hepatocellular Carcinoma (S781) [J]. Journal of Pain and Symptom Management, 2017, 53 (2), 455-455.
Villanueva Augusto. Hepatocellular Carcinoma. [J]. The New England journal of medicine, 2019, 380 (15), 1450-1462.
Forner Alejandro, Reig María, Bruix Jordi. Hepatocellular carcinoma. [J]. Lancet (London, England), 2018, 391 (10127), 1301-1314.
Feng Xiujuan. Status and related factors of cancer-induced fatigue in colorectal cancer patients based on the theory of unpleasant symptoms [D]. Shandong university, 2019.
Su Xin. A dynamic study on symptom group and quality of life in postoperative chemotherapy for gastric cancer patients [D]. Shanxi medical university, 2019.
Wang Zequan. Symptom cluster and quality of life of hospitalized patients with heart failure [D]. Jilin university, 2018.
Peng Xue. The mediating effect of emotion on symptom group and quality of life in patients with intestinal stoma [D]. Shandong university, 2019.
Bejarano Suyapa, Freed Meghan E, Zeron Darwin, Medina Rennie, Zuniga-Moya Julio Cesar, Kennedy Linda, Bruce Martha L, Zubkoff Lisa, Bakitas Marie A, Lyons Kathleen Doyle. Feasibility of a Symptom Management Intervention for Honduran Adults Undergoing Chemotherapy. [J]. Western journal of nursing research, 2019, 41 (10).
Bejoy C. Thomas, Amy Waller, Rebecca L. Malhi, Tak Fung, Linda E. Carlson, Shannon L. Groff, Barry D. Bultz. A Longitudinal Analysis of Symptom Clusters in Cancer Patients and Their Sociodemographic Predictors [J]. Journal of Pain and Symptom Management, 2014, 47 (3).
Lee Seung Eun, Vincent Catherine, Finnegan Lorna. An Analysis and Evaluation of the Theory of Unpleasant Symptoms. [J]. ANS. Advances in nursing science, 2017, 40 (1).
Dodd M, Janson S, Facione N, Faucett J, Froelicher E S, Humphreys J, Lee K, Miaskowski C, Puntillo K, Rankin S, Taylor D. Advancing the science of symptom management. [J]. Journal of Advanced Nursing, 2001, 33 (5).
Kim Hee-Ju, McGuire Deborah B, Tulman Lorraine, Barsevick Andrea M. Symptom clusters: concept analysis and clinical implications for cancer nursing. [J]. Cancer nursing, 2005, 28 (4), 270-282.
BARSEVICK A M. The elusive concept of the symptom cluster [J]. Oncology Nursing Forum, 2007, 34 (5): 971-980.
Zhu Zheng, Zhao Rui, Hu Yan. Symptom Clusters in People Living With HIV: A Systematic Review. [J]. Journal of pain and symptom management, 2019, 58 (1), 115-133.
DeVon HA, Vuckovic K, Ryan CJ, et al. Systematic review of symptom clusters in cardiovascular disease. Eur J Cardiovasc Nurs 2017; 16: 6e17.
Dong ST, Butow PN, Costa DS, Lovell MR, Agar M. Symptom clusters in patients with advanced cancer: a systematic review of observational studies. J Pain Symptom Manage 2014; 48: 411e450.
Cao wenting, sun haiying, hu Chen, li Juan, shen jie, xu yan. Study on the symptom group of patients with liver cancer treated by transcatheter hepatic arterial chemoembolization [J]. Nursing research, 2012, 26 (20): 1844-1846.
Ryu Eunjung, Kim Kyunghee, Cho Myung Sook, Kwon In Gak, Kim Hee Sun, Fu Mei R. Symptom clusters and quality of life in Korean patients with hepatocellular carcinoma.[J]. Cancer nursing, 2010, 33 (1), 3-10.
Chung Meng-Hua, Wang Shu-Yi, Lin Chia-Chin. Symptom Clusters and Impact of Fatigue and Sleep Disturbance on Symptom Experiences of Hepatoma Patients in Taiwan.[J]. Cancer nursing, 2017, 40 (5), 403-411.
Zhong hong, LuHuijuan, Li Xiaorong, Qin Wei, Wei Linbo. A comparative analysis of the symptom group of hepatocellular carcinoma patients after hepatic arterial chemoembolization [J]. Journal of nursing science, 2014, 29 (04): 15-18.
Ma Hongqi, Xiao Xiangmin, Guo Yabo, Li Qiong. Study on perioperative symptom group and related factors in patients with primary liver cancer [J]. Journal of nursing, 2008, 33 (04): 19-23.
Wang Yixin, O'Connor Margaret, Xu Yan, Liu Xiaohong. Symptom clusters in Chinese patients with primary liver cancer. [J]. Oncology nursing forum, 2012, 39 (6), 468-479.
Zhang h, guo y J, wang r, zhou l q, li x. Study on the symptom group of patients with primary liver cancer treated by ultrasound-guided percutaneous microwave ablation [J]. Cancer progression, 209, 17 (01): 112-115.
Xiao Xiao, Chen Dongfeng. Progress of FOLFOX4 regimen in the treatment of liver cancer [J]. Chongqing medical science, 2016, 45 (01): 120-122.
Zhang Ying, Qiang Wanmin, Chen Yuhong, Ren Jialei. Bibliometric analysis of an investigational study on breast cancer survivors [J]. Journal of nursing education, 204, 34 (20): 1868-1874.
Bovio G, Montagna G, Bariani C, et al. Upper gastrointestinal symptoms in patients with advanced cancer: relationship to nutritional and performance status. Support Care Cancer, 2009, 17 (10): 1317-1324.
Kim E, Jahan T, Aouizerat BE, et al. Changes in symptom clusters in patients undergoing radiation theray. Support Care Cancer, 2009, 17 (11): 1383-1391.
HILARIUS D L, KLOEG P H, VAN DER WALL E, et al. Chemotherapy-induced nausea and vomiting in daily clinical practice: a community hospital-based study [J]. Support Care Cancer, 2012, 20 (1): 107-117.
LAVIANO A, KOVERECH A, SEELAENDER M. Assessing pathophysiology of cancer anorexia [J]. Curr Opin Clin Nutr MetabCare, 2017, 20 (5): 340-345.
Ma huaixing, li suyi. Pathogenesis and diagnosis of anorexia in tumors [J]. Cancer metabolism and nutrition, 2018 (2): 117 121.
Tang Lili, Zhang Yening, Pang Ying. Patient-reported outcomes from the distress assessment and response tool program in Chinese cancer inpatients.[J]. Psycho-oncology, 2020.
Knoerl, Robert; Chornoby, Zach; Smith, Ellen M. L. Estimating the Frequency, Severity, and Clustering of SPADE Symptoms in Chronic Painful Chemotherapy-Induced Peripheral Neuropathy. [J]. PAIN MANAGEMENT NURSING, 2018, 19 (4): 354-365.
Skye T. Dong, Daniel S. J. Costa, Phyllis N. Butow, Melanie R. Lovell, Meera Agar, Galina Velikova, Paulos Teckle, Allison Tong, Niall C. Tebbutt, Stephen J. Clarke, Kim van der Hoek, Madeleine T. King, Peter M. Fayers. Symptom Clusters in Advanced Cancer Patients: An Empirical Comparison of Statistical Methods and the Impact on Quality of Life [J]. Journal of Pain and Symptom Management, 2016, 51 (1): op88-98.
Zhao Jiang. Research and development of Chinese version of RSCL and its correlation with symptom experience and quality of life of patients with primary hepatocellular carcinoma [D]. Anhui medical university, 2011.
Qin Lun-Xiu, Tang Zhao-You. Hepatocellular carcinoma with obstructive jaundice: diagnosis, treatment and prognosis. [J]. World journal of gastroenterology, 2003, 9 (3), 385-391.