Clinical and Pathological Aspects of the Sequelae of Urogenital Schistosomiasis: Findings Regarding 43 Cases
International Journal of Clinical Urology
Volume 3, Issue 1, June 2019, Pages: 10-14
Received: Apr. 28, 2019;
Accepted: Jun. 2, 2019;
Published: Jun. 12, 2019
Views 399 Downloads 69
Boubacar Fall, Department of Urology, Aristide Le-Dantec Hospital, Dakar, Senegal
Yaya Sow, Department of Urology, Aristide Le-Dantec Hospital, Dakar, Senegal
Aboubacar Traoré, Department of Urology, Aristide Le-Dantec Hospital, Dakar, Senegal
Cyrille Ze Ondo, Department of Urology, Aristide Le-Dantec Hospital, Dakar, Senegal
Mouhamedou Diagana, Department of Urology, Cheikh Zayed Hospital, Nouakchott, Mauritania
Alioune Sarr, Department of Urology, Aristide Le-Dantec Hospital, Dakar, Senegal
Babacar Sine, Department of Urology, Aristide Le-Dantec Hospital, Dakar, Senegal
Samba Thiapato Faye, Department of Urology, Aristide Le-Dantec Hospital, Dakar, Senegal
Modou Ndiaye, Department of Urology, Aristide Le-Dantec Hospital, Dakar, Senegal
Ousmane Sow, Department of Urology, Aristide Le-Dantec Hospital, Dakar, Senegal
Mamadou Ba, Department of Urology, Aristide Le-Dantec Hospital, Dakar, Senegal
Follow on us
Purpose: To describe the clinical-pathological profile of sequelae of urogenital schistosomiasis. Patients and methods: We performed a retrospective study of the sequelae for cases of urogenital schistosomiasis treated between January 2011 and December 2016. These cases were from Senegal and neighboring countries. Results: We included 43 cases. The mean age of the patients was 43.2 ± 16.6 years (14 - 75 years). The sex ratio was 3.3. The sites of the sequelae lesions were the bladder and pelvic ureters in 83.7%, the bladder only in 13.9%, and the ureters only in 2.3% of the patients. Bladder wall calcification was the most common lesion (74.4%), followed by bladder masses (48.8%). Stenosis of the orifice was the most common ureteral lesion (30.2%). The bladder masses were a squamous cell carcinoma in ten cases, a urothelial carcinoma in one case, and a schistosomiasis granuloma in five cases. In one patient, the histological type was not specified. Of the ten cases of squamous cell carcinoma, eight had died of cancer. Of the twelve cases of ureteral orifice stenosis treated by ureterocystoneostomy, the outcome was good in nine cases and poor in three patients. Conclusion: In this study, sequelae of urogenital schistosomiasis were most often observed in young adult males. The most common sequelae were vesical and ureteral calcifications, bladder cancers, and pelvic ureter strictures.
Urogenital Schistosomiasis, Calcifications, Bladder Cancer, Urinary Obstruction
To cite this article
Cyrille Ze Ondo,
Samba Thiapato Faye,
Clinical and Pathological Aspects of the Sequelae of Urogenital Schistosomiasis: Findings Regarding 43 Cases, International Journal of Clinical Urology.
Vol. 3, No. 1,
2019, pp. 10-14.
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Ziskind B. Urinary schistosomiasis in ancient Egypt. Nephrol Ther 2009; 5: 658-61. https://doi.org/10.1016/j.nephro.2009.06.001.
Mianné D, Perret JL, Lavilledieu S. Bilharziose urogénitale. Encycl. Méd. Chir. (Elsevier Paris). Néphrologie urologie.18-230. A10.1998, 13p.
Karl-Horst Bichler, Ilya Savatovsky and the members of the urinary tract infection (UTI) working group of the guidelines office of the European Association of Urology (EAU): EAU guidelines for the management of urogenital schistosomiasis. Eur Urol 2006; 49: 998-1003. https://doi.org/10.1016/j.eururo.2006.02.022.
Senghor B, Diallo A, Sylla SN, Doucouré S, Ndiath MO, Gaayeb L, et al. Prevalence and intensity of urinary schistosomiasis among school children in the district of Niakhar, region of Fatick, Senegal. Parasit Vectors 2014; 7: 5. https://doi.org/10.1186/1756-3305-7-5.
Diao B, Thiam A, Fall B, Fall PA, Diémé MJ, Ndoye AK, et al. Bladder cancer in Senegal: epidemiological, clinical and histological features. Prog Urol 2008; 18: 445-8. https://doi.org/10.1016/j.purol.2008.04.016.
Shebel HM, Elsayes KM, Abou El Atta HM, Elguindy YM, El-Diasty TA. Genitourinary schistosomiasis: Life cycle and radiologic-pathologic findings. RadioGraphics 2012; 32: 1031-46. https://doi.org/10.1148/rg.324115162.
Barsoum RS. Urinary schistosomiasis. J Adv Res 2013; 4: 453-9. https://doi.org/10.1016/j.jare.2012.08.004.
Ferguson AR. Associated bilharziasis and primary malignant disease of the urinary bladder with observations on a series of forty cases. J Pathol Bacteriol 1911; 16: 76-94.
World Health Organization. Evaluation of carcinogenic risk to humans. Schistosomes, liver flukes and Helicobacter pylori. IARC Monogr 1994; 61: 45 -119.
Berry A, Iriart X, Fillaux J, Magnaval JF. Urinary Schistosomiasis and Cancer. Bull Soc Pathol Exot 2017; 110: 68 -75.
Khaled H. Schistosomiasis and Cancer in Egypt. J Adva Res 2013; 4: 461-6. https://doi.org/10.1016/j.jare.2013.06.007.
Zaghloul MS. Bladder cancer and schistosomiasis. J Egypt Natl Canc Inst 2012; 24: 151–159. https://doi.org/10.1016/j.jnci.2012.08.002.
Abdou A, Tligui M, Le Loup G, Raynal S. A western cohort of urinary schistosomiasis. Prog Urol 2012; 22: 598-601. https://doi.org/10.1016/j.purol.2012.03.004.
Diallo M, Guindo M, Kane B, et al. Evaluation des séquelles bilharziennes du tractus uro –génital par uro-scanner au CHU Gabriel Traoré Bamako-Mali. J Afr Imag Med 2013; 4: 229-35.
De la Taille A, Ravery V, Hoffmann P, et al. Treatment of ureteral stenosis using high pressure dilatation catheters. Prog Urol 1997; 7: 408-14.