Clinical Effects of Safflower Pill of Dedu Seven Medicinal Herbs Plus Adefovir Dipivoxil on Liver Fibrosis Resulting from Chronic Viral Hepatitis B
International Journal of Biomedical Science and Engineering
Volume 5, Issue 3, June 2017, Pages: 24-28
Received: Jun. 6, 2017; Published: Jun. 6, 2017
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Authors
Yi Na, College of Pharmacy, Inner Mongolia Medical University, Hohhot, P. R. China
Siwen Wei, College of Pharmacy, Inner Mongolia Medical University, Hohhot, P. R. China
Xiaoran Wang, College of Pharmacy, Inner Mongolia Medical University, Hohhot, P. R. China
Yi Wang, Department of Pharmacy, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, P. R. China
Ruilian Ma, Department of Pharmacy, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, P. R. China
Lidao Bao, Department of Pharmacy, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, P. R. China
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Abstract
To study the clinical effects of Safflower Pill of Dedu Seven Medicinal Herbs combined with Adefovir Dipivoxil on liver fibrosis resulting from chronic viral hepatitis B.116 patients with chronic hepatitis B fibrosis were randomly divided into two groups (n=58 for each group): treatment group (Safflower Pill of Seven Medicinal Herbs combined with Adefovir Dipivoxil) and control group (Adefovir Dipivoxil) (n=58) for clinical observation of 24 weeks. After 24 weeks, the effective rates were 93.10% and 81.03% in the treatment group and control group respectively; the indexes of liver function, liver fibrosis and radiographic indexes of the patients in both groups were significantly decreased (P <0.05 or P <0.01); The differences between the two groups were statistically significant (P <0.05). The effect of Safflower Pill of Seven Medicinal Herbs combined with Adefovir Dipivoxil for the treatment of chronic hepatitis B fibrosis is more effective than that of Adefovir Dipivoxil alone.
Keywords
Adefovir Dipivoxil, Chronic Viral Hepatitis B, Liver Fibrosis, Safflower Pill of Seven Medicinal Herbs
To cite this article
Yi Na, Siwen Wei, Xiaoran Wang, Yi Wang, Ruilian Ma, Lidao Bao, Clinical Effects of Safflower Pill of Dedu Seven Medicinal Herbs Plus Adefovir Dipivoxil on Liver Fibrosis Resulting from Chronic Viral Hepatitis B, International Journal of Biomedical Science and Engineering. Vol. 5, No. 3, 2017, pp. 24-28. doi: 10.11648/j.ijbse.20170503.12
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