A Review of the Molecular Pathways of Oncogenic HPV and Targeted the Rapies in Carcinoma of the Uterine Cervix
Advances in Surgical Sciences
Volume 5, Issue 1, February 2017, Pages: 1-6
Received: Feb. 25, 2017; Accepted: Mar. 25, 2017; Published: Apr. 12, 2017
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Author
Boniface Uji Ago, Department of Obstetrics and Gynaecology, University of Calabar Teaching Hospital, Calabar, Nigeria
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Abstract
Cervical carcinoma is a preventable disease based on its etiopathogenesis. This relies highly on its prompt diagnosis and treatment based on effective screening and treatment methods. Knowledge of its molecular pathways will drive the use of targeted therapies in the treatment of the disease. The objectives of this review are: to explore the biology and immunology of HPV; the various molecular pathways through which oncogenic HPV destroys normal cervical cells; and targeted therapies. Several molecular pathways have been identified but the use of drugs to act on specified molecular targets are at different stages of clinical trials.
Keywords
Cervical Cancer, Molecular Pathways, Targeted Therapies
To cite this article
Boniface Uji Ago, A Review of the Molecular Pathways of Oncogenic HPV and Targeted the Rapies in Carcinoma of the Uterine Cervix, Advances in Surgical Sciences. Vol. 5, No. 1, 2017, pp. 1-6. doi: 10.11648/j.ass.20170501.11
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Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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