Drug Compliance in Children with Juvenile Idiopathic Arthritis and Reasons for Poor Compliance
American Journal of Clinical and Experimental Medicine
Volume 5, Issue 1, January 2017, Pages: 15-18
Received: Dec. 14, 2016;
Accepted: Dec. 27, 2016;
Published: Jan. 23, 2017
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Mohammad Humayun Kabir, Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Kamrul Laila, Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Mujammel Haque, Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Shahana Akhter Rahman, Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
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Children with chronic disorders are at risk for a higher medication non-adherence. Juvenile idiopathic arthritis (JIA) is a chronic childhood disorder where often medication non-adherence is an issue. The purpose of this study was to assess drug compliance of JIA patients,to find out the proportion of patients having poor drug compliance and to find out possible reasons of poor drug compliance. This was a retrospective study conducted in the Pediatric Rheumatology follow up clinic, Department of Pediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. All JIA patients attending pediatric rheumatology follow up clinic during the study period was included. Data were collected using a structured questionnaire. Among the total 900 registered JIA cases, 116(12.9%) patients had poor compliance. Among 116 poor compliant patients, systemic onset JIA cases were the highest (34.5%), followed by enthesitis related arthritis (30.2%). Among the poor compliant patients, 6.9% patients had regular follow up and 93.1% had irregular follow up. Major reasons of poor compliance were financial crisis, lack of awareness and difficulty in transportation. Poor compliance to treatment of JIA in our setting was common. The most important reason for poor compliance was financial crisis.
Juvenile Idiopathic Arthritis, Poor Compliance, Follow Up
To cite this article
Mohammad Humayun Kabir,
Shahana Akhter Rahman,
Drug Compliance in Children with Juvenile Idiopathic Arthritis and Reasons for Poor Compliance, American Journal of Clinical and Experimental Medicine.
Vol. 5, No. 1,
2017, pp. 15-18.
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Klein A, Kaul I, Foeldvari I, Ganser G, Urban A & Horneff G. Efficacy and safety of oral and parenteral methotrexate therapy in children with juvenile idiopathic arthritis: An observational study with patients from the German Methotrexate Registry. Arthritis Care Res 2012; vol. 64(9), pp. 1349-1356.
World Health Organization. WHO Report on Medication Adherence, Using teach-back for patient education and self-management. American Nurse Today 2011; vol. 7(3), pp. 1-3.
Viswanthan M, Golin CE & Jones CD. Interventions to improve adherence to self-administered medications for chronic diseases in the United States: A systematic review. Ann Intern Med 2012; vol. 157 (11), pp. 785-795.
Heidenreich PA. Patient adherence: The next frontier in quality improvement. Am. J. Med 2004; vol. 1(17), pp. 130-132.
Pelajo CF, Sgarlat CM, Lopez-Benitez JM, Oliveira SKF, Rodrigues MCF & Szatanjbok FR. Adherence to methotrexate in juvenile idiopathic arthritis. Rheumatol Int. 2012; vol. 32, pp. 497-500.
Bugni VM, Ozaki LS, Okamoto KY, Barbosa CM, Hilario MO & Len CA et al. Factors associated with adherence to treatment in children and adolescents with chronic rheumatic diseases. J. Pediatr 2012;vol. 88 (6), pp. 483-488.
Feldman DE, De Civita M, Dobkin PL, Malleson P, Meshefedjian G & Duffy CM. Perceived adherence to prescribed treatment in juvenile idiopathic arthritis over a one-year period. Arthritis Rheumatol 2007; vol. 57, pp. 226-233.
Senzaki, Susan Viola, "Identifying Factors in Medication Non-Adherence in Teens Diagnosed with Juvenile Arthritis: A Pilot Study"(2015). Doctoral Projects. Paper 3.
Rapoff MA, Belmont J, Lindsley C, Olson N, Morris J &Padur J. Prevention of non-adherence to non steroidal anti-inflammatory medications for newly diagnosed patients with juvenile rheumatoid arthritis. Health Psychol 2002; vol. 21(6), pp. 620-623.
Kessels RP. Patients’ memory for medical information. J R Soc Med. May 2003; 96(5):219-22.
Rapoff MA. Management of adherence and chronic rheumatic disease in children and adolescents. Best Prac. Res.Clin. Rheumatol 2006; vol. 20(2), pp. 301-314.