The Trend Towards the Right (Proximal) Shift of Colorectal Cancer: Is Not Observed in Sudanese Patients
American Journal of Clinical and Experimental Medicine
Volume 4, Issue 5, September 2016, Pages: 156-159
Received: Sep. 6, 2016;
Accepted: Sep. 21, 2016;
Published: Oct. 18, 2016
Views 3139 Downloads 80
Hyder Osman Mirghani, Department of Internal Medicine, Faculty of Medicine, University of Tabuk, Tabuk, Kingdom of Saudi Arabia
Ali Adam Elhadi, Department of Internal Medicine, Medical College, Omdurman Islamic University, Omdurman, Sudan
Ibrahim Abdullah Albalawi, Department of Surgery, Faculty of Medicine, University of Tabuk, Tabuk, Kingdom of Saudi Arabia
Background: There is a tendency of colorectal cancer towards a right shift, and increasing incidence among the young age groups. In this study, we aimed to assess the pattern of colorectal cancer among Sudanese patients attending an endoscopy unit in Omdurman Teaching Hospital. Subjects and Methods: This descriptive cross- sectional study conducted among thirty patients referred with the provisional diagnosis of colorectal cancer during the period from August 2015 to June 2016. Participants signed a written informed consent then interviewed to collect demographic data, symptoms related to carcinoma of the colon, the patients were then examined for evidence of anemia, intestinal obstruction, and ascites, colonoscopy with biopsy for histopathology was done. The ethical committee of the Omdurman Teaching Hospital approved the research, and the Statistical Package for Social Sciences (SPSS) was used for data analysis. Results; Out of thirty patients with the diagnosis of colorectal cancer, their ages ranged from 18-76 years with a mean of 51.1. The commonest presentations were rectal bleeding, change in the bowel habits, and constipation in 90%, 80%, and 60% respectively. Fourteen (46.7% were ≤ 50 years. The family history of colorectal cancer was evident in 16.7%, the recto-sigmoid area was the commonest site (83.3%), with 100% adenocarcinoma. Conclusion: Colorectal cancer tend to affect the younger age groups, the majority were recto-sigmoid (the proximal shift was not observed). The adenocarcinoma was the commonest histopathology.
Hyder Osman Mirghani,
Ali Adam Elhadi,
Ibrahim Abdullah Albalawi,
The Trend Towards the Right (Proximal) Shift of Colorectal Cancer: Is Not Observed in Sudanese Patients, American Journal of Clinical and Experimental Medicine.
Vol. 4, No. 5,
2016, pp. 156-159.
Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Amany Elamin, Muntaser E Ibrahim, Dafalla Abuidris, Kamal Eldin H Mohamed, and Sulma Ibrahim Mohammed. Part I: cancer in Sudan—burden, distribution, and trends breast, gynecological, and prostate cancers. Cancer Med. 2015 Mar; 4 (3): 447–456.
Chalya PL, McHembe MD, Mabula JB, Rambau PF, Jaka H, Koy M, Mkongo E, Masalu N. Clinicopathological patterns and challenges of management of colorectal cancer in a resource-limited setting: a Tanzanian experience. World J SurgOncol. 2013 Apr 18; 11: 88. doi: 10.1186/1477-7819-11-88.
World Health Organization, author. Cancer. Fact Sheet (No. 297) Geneva: 2006.http://www.who.int/mediacentre/factsheets/fs297/en/print.html.
Intisar E Saeed, Hsin-Yi Weng, Kamal H Mohamed, and SulmaMohammed. Cancer incidence in Khartoum, Sudan: first results from the Cancer Registry, 2009–2010. Cancer Med. 2014 Aug; 3 (4): 1075–1084.
ParthPatela, Prithwish De. Trends in colorectal cancer incidence and related lifestyle risk factors in15–49-year-olds in Canada, 1969–2010. Cancer Epidemiology 42 (2016) 90–100.
Khan T, Kayani N, Ahmad R, Usman A, Bhurgri A, Bashir I, Hasan SH, Zaidi S, Bhurgri Y. Incidence and current trends of colorectal malignancies in an unscreened, low risk Pakistan population. Asian Pac J Cancer Prev.2011; 12 (3): 703-8.
Group WB. 2012. Washington, DC, USA World Bank Publications World Development Indicators 2012.
Ghahremani GG, Dowlatshahi K. Colorectal carcinomas: diagnostic implications of their changing frequency and anatomic distribution. World J Surg. 1989 May-Jun; 13 (3): 321-4; discussion 324-5.
Ponz de Leon M, Marino M, Benatti P, Rossi G, Menigatti M, Pedroni M, Di Gregorio C, Losi L, Borghi F, Scarselli A, Ponti G, Roncari B, Zangardi G, Abbati G, Ascari E, Roncucci L. Trend of incidence, subsite distribution and staging of colorectal neoplasms in the 15-year experience of a specialised cancer registry. Ann Oncol. 2004 Jun; 15 (6): 940-6.
Rabeneck L, Davila JA, El-Serag HB. Is there a true "shift" to the right colon in the incidence of colorectal cancer? Am J Gastroenterol. 2003 Jun; 98 (6): 1400-9.
Taha MO, Abdalla AA, Mohamed RS. Pattern & presentation of colorectal cancer in central Sudan, a retrospective descriptive study, 2010–2012. Afr Health Sci. 2015 Jun; 15 (2): 576–580.
Mohammed M, Mussad A, Eltayeb E, A elaziz M. Clorectal carcinoma in Sudanese patients. International journal of medicine 2015; 3 (2): 98-102
Albasri A, Yosef H, Hussainy AS, Sultan SA, Alhujaily A. Histopathological features of colorectal cancer in Al-Madinah region of Saudi Arabia: 8 years experience. Asian Pac J Cancer Prev. 2014; 15 (7): 3133-7.
Nørgaard M, Farkas DK, Pedersen L, Erichsen R, de la Cour ZD, Gregersen H, Sørensen HT. Irritable bowel syndrome and risk of colorectal cancer: a Danish nationwide cohort study. Br J Cancer. 2011 Mar 29; 104 (7): 1202-6. doi: 10.1038/bjc.2011.65. Epub 2011 Feb 22.