Evaluation of the Effect of Ayurvedic Herbo-minaral Formulation: Chandraprabha vati on Albuminuria
American Journal of Clinical and Experimental Medicine
Volume 3, Issue 5, September 2015, Pages: 300-305
Received: Nov. 30, 2015;
Published: Dec. 1, 2015
Views 3903 Downloads 88
Weerasekera K. R., Department of Nidana Chikitsa, Institute of Indigenous Medicine, University of Colombo, Rajagiriya, Sri Lanka
Dhammarathana I., Deparment of Sanskrit, University of Kelaniya, Kelaniya, Sri Lanka
Tissera M. H. A., Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka
Ariyawansa H. A. S., Department of Nidana Chikitsa, Institute of Indigenous Medicine, University of Colombo, Rajagiriya, Sri Lanka
Follow on us
Ayurveda is a science of life, based on its basic principles, time tested and experienced through centuries. It is an evidence of experimental research in Ayurveda and proves that Ayurveda has its own scientific methodology of research and this could be effectively tested with ailments like albuminuria. Albuminuria is a one of the early symptoms of chronic kidney diseases (CKD) and CKD is a very common disorder in present era. For albuminuria, Chandraprabha vati is a commonly used Ayurvedic drug and its efficacy on albuminuria is not scientifically validated yet. Therefore this clinical study was aimed at to re- establish the efficacy of Ayurvedic formulation Chandraprabha vati on albuminuria, which can be compared to some of the types of disease of Prameha (urine abnormality) in Ayurveda, along with the assessment of the effects on the basis of scientific, disease specific biochemical parameter. Hundred patients with albuminuria were selected randomly and divided into two groups, group1was treated with Chandraprabha vati (1000 mg twice daily) and the other was considered as placebo. The results review that the Candraprabha vati has significantly reduced the signs and symptoms of albuminuria, mainly albuminin urine and although turbidity, organisms, pus cells, red cells, colour and frequency of urine and as well as the some pre-monitory symptoms of disease of Prameha. In the light of the results obtained this study proved the fact that Chandraprabha vati has been immensely effective and safe Ayurvedic drug and particularly been the vital factor in reducing the level of albuminin urine significantly in conclusion.
Albuminuria, Candraprabha vati, Chronic Kidney Diseases, Prameha
To cite this article
Weerasekera K. R.,
Tissera M. H. A.,
Ariyawansa H. A. S.,
Evaluation of the Effect of Ayurvedic Herbo-minaral Formulation: Chandraprabha vati on Albuminuria, American Journal of Clinical and Experimental Medicine.
Vol. 3, No. 5,
2015, pp. 300-305.
Saranghadhara Samhita by Pandit Sharanghadharacharya with the Commentary of Kashinatha Shastrina (Sanskrit). (1936). Sastri, P. (edi). Sri Rama Presayantralayemudrita, India. Pp 131-132.
ESRD as a Window into America's Cost Crisis in Health Care. Felix Knauf and Peter S. Aronson. Journal American Society Nephrology, 2009; doi: 10.1681/ASN. 2009070715.
Hittarage A. Chronic renal disease in North Central Province of Sri Lanka. Anuradhapura Medical Journal; 2004:3-5.
National Kidney Foundation: K/DOQI clinical practice guide lines for chronic kidney disease: evaluation, classification, and stratification. American Journal of Kidney Disease2002; 39:S1-266.
Pendergraph, B. (2005). Detection and evaluation of Chronic Kidney Disease, 2005, N Engl J Med.
Nimmi T.C. Athuraliya, Thilak D. J. Abeysekera, Priyanie H. Amerasinghe, Ranjit Kumarasiri, Palitha Bandara, Upul Karunaratne, Abul H. Milton and Alison L. Jones. Uncertain etiologies of proteinuric chronic kidney disease in rural Sri Lanka. Kidney International 2011; 80:1212–1221.
Caraka Samhita with Ayurvedadipika commentaries of Cakrapanidatta and Jalpakalpataru explanatory notes of Sri Gangadhar (Sanskrit): (1991). Senagupta, N., and Senagupta, B. (edi). Chaukhambha Orientalia, Varanasi, India.
Ayurveda Aushada Samgrahaya. (1976). Department of Ayurveda, Colombo, Sri Lanka.
Reddy, K.R.C. (2004). Bhaisajya Kalpana Vijnanam. Chawkhamba Sanskrit Bhavan,Varanasi, India.
Sharma, P.V. (1956). Dravya Guna Vignana (Sanskrit). The Chawkhamba Vidya Bhavan, Benaras, India.
Diuretic activity of Chandraprabha Vati, Ratnasooriya WD., Weerasekera KR., Dhammarathana I., Tissera AHM., Ariyawansha HAS., World Journal of Pharmaceutical Sciences, 2014; 2(7); 648-653.
Anti-inflammatory activity of an Ayurvedic herbo-mineral formulation: Chandraprabha vati, Weerasekera KR., Dhammarathana I, Tissera MHA, Ariyawansha HAS, Ratnasooriya WD., International Journal of Recent Advances in Multi disciplinary Research, Vol 02, Issue 06, p471-475.
Investigation of antioxidant activity of an ayurvedic formulation Chandraprabha vati, Weerasekera KR., Ranasingha P, Dhammarathana I., Tissera AHM., Ariyawansha HAS., Sri Lanka Journal of Indigenous Medicine, 2013;03(02):187-190.