Absolute Neutrophil Count as a Septic Shock Predictor in Pediatric Emergency Room
American Journal of Clinical and Experimental Medicine
Volume 3, Issue 2, March 2015, Pages: 68-72
Received: Mar. 9, 2015; Accepted: Mar. 22, 2015; Published: Mar. 26, 2015
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Authors
Lucy Amelia, Department of Pediatrics, Medical Faculty of Hasanuddin University, Makassar, South Sulawesi, Indonesia
Idham Jaya Ganda, Department of Pediatrics, Medical Faculty of Hasanuddin University, Makassar, South Sulawesi, Indonesia
Dasril Daud, Department of Pediatrics, Medical Faculty of Hasanuddin University, Makassar, South Sulawesi, Indonesia
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Abstract
Introduction: The Absolute Neutrophil Count (ANC) is a neutrophil percentage multiplied by the total leukocytes in blood. Its use as a prognostic indicator has been studied in a variety of circumstances, especially sepsis in the neonates and children. Objective: This research aims to investigate the roles of the ANC as the predictor of the septic shock. Methods: It was a prospective cohort study. The data were collected when the patients were brought into the Pediatric Emergency Room (PER) of Dr. Wahidin Sudirohusodo Hospital, Makassar in September through December 2012. The ANC total of the treated patients was counted and then the patients were put into two groups: the group with ANC < 1500/mm3 and the group with ANC ≥ 1500/mm3. The individual health condition of each ANC group was observed carefully in order to determine whether the patients suffered from the septic shock or not. Results: The incidence of the septic shock in the ANC group of < 1500/mm3 was greater compared to that of ≥ 1500/mm3 with the p value = 0.015 (p < 0.05). Besides, it was found that the odds ratio = 6.333, CI = 95% (1.523 – 26.335). No significant differences of septic shock incidence were found between age, nutritional status, sex and infectious/non infectious disease. Conclusion: The mean value of the ANC in patients with septic shock is lower compared with non septic shock. The incidence of septic shock in patients with ANC ≥ 1500/ mm3 group; ANC can be used as predictor of impending the septic shock.
Keywords
Septic Shock, Sepsis, ANC, Predictor Factor, Children
To cite this article
Lucy Amelia, Idham Jaya Ganda, Dasril Daud, Absolute Neutrophil Count as a Septic Shock Predictor in Pediatric Emergency Room, American Journal of Clinical and Experimental Medicine. Vol. 3, No. 2, 2015, pp. 68-72. doi: 10.11648/j.ajcem.20150302.14
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