Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia
American Journal of Clinical and Experimental Medicine
Volume 2, Issue 6, November 2014, Pages: 128-131
Received: Oct. 10, 2014; Accepted: Nov. 6, 2014; Published: Nov. 20, 2014
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Salil Vaniawala, Molecular Cytogenetic Unit, S. N. Gene Laboratory and Research Centre, President Plaza-A , Near RTO circle, Surat-395001, India
Gadhia Pankaj, P. K. Gadhia, Molecular Cytogenetic Unit, S. N. Gene Lab. and Research Centre, Near RTO circle, Surat – 395001. India
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In the present study, we screened the bone marrow chromosome database entries between March, 2004 and December, 2013 to identify cases with inv(9) along with t(9;22) variations. Our study recorded 2300 cases of confirmed CML (Ph positive), of which only 12 (0.52%) cases had inv(9) and t(9;22). The association between inv(9) and t(9;22) is not fully explored. Therefore more number of cases is required to shed light on its important role, if any, especially in bone-marrow transplantation and drug resistance.
Pericentric Inv (9), CML, t(9; 22), Bone-Marrow
To cite this article
Salil Vaniawala, Gadhia Pankaj, Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia, American Journal of Clinical and Experimental Medicine. Vol. 2, No. 6, 2014, pp. 128-131. doi: 10.11648/j.ajcem.20140206.13
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