Clinical Aspects of Juvenile Idiopathic Arthritis: Extended Experience from Bangladesh
American Journal of Clinical and Experimental Medicine
Volume 1, Issue 1, July 2013, Pages: 20-23
Received: Jun. 13, 2013;
Published: Jul. 10, 2013
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Shahana A Rahman, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Mohammad Imnul Islam, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Manik Kumar Talukder, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Objectives: To assess the different clinical aspects of JIA patients as well as the disease activity status during follow-up period. This study also compared its findings with the previous baseline study done in our country. Methodology: A prospective observational study carried out in the department of pediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh during the study period of January 2004 to December 2012. A total of 415 patients according to ILAR criteria were enrolled in the study. Patients who completed a 2 year follow-up period were assessed for disease activity status according to Wallace criteria. Data was collected in a predesigned questionnaire. Results: Among the 415 cases, M: F ratio was approximately 2:1. Age range of the patients was 14 months to 16 years. Highest number of patients were present in the age group 11-16 years (49%) followed by 6-10 years. The duration of illness was more than 12 months in the majority. Polyarticular RF negetive patients were most frequent (33%), followed by persistent oligo-arthritis (28 %). Among the patients who completed at least 2 years of follow-up, 68% achieved remission, of them 51% maintained remission and 16.3% had relapse. Conclusion: Late diagnosis with long duration of disease was still common. Clinical profile of this study was almost similar to our previous study but differed from western JIA cases mainly in term of sex, subtypes and duration of illness. Majority of the patients went into remission. Wrong diagnosis was gradually decreasing and it seems that awareness about JIA is gradually increasing among the medical professionals in our country.
Shahana A Rahman,
Mohammad Imnul Islam,
Manik Kumar Talukder,
Clinical Aspects of Juvenile Idiopathic Arthritis: Extended Experience from Bangladesh, American Journal of Clinical and Experimental Medicine.
Vol. 1, No. 1,
2013, pp. 20-23.
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