Clinical and Laboratory Profile of Patients Admitted with Cleistanthus Collinus Poisoning in a Tertiary Care Hospital
American Journal of Internal Medicine
Volume 3, Issue 6-1, November 2015, Pages: 14-17
Received: Sep. 19, 2015; Accepted: Sep. 22, 2015; Published: Oct. 23, 2015
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Authors
Ramya Das N. K., Department of General Medicine, Government Medical College, Thrissur, India
Mary Grace N. C., Department of General Medicine, Government Medical College, Thrissur, India
Indira M., Department of General Medicine, Government Medical College, Thrissur, India
Jayachandran N. V., Department of General Medicine, Government Medical College, Thrissur, India
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Abstract
Cleistanthus collinus (Oduku) is a common suicidal poison used in rural southern India. There is paucity of information on human studies about this poisoning at global level. We conducted a cross-sectional observatory study to analyse clinical and laboratory profile of patients admitted with Oduku poisoning in Department of General Medicine, Government medical college, Thrissur over a period of one year from 1st January 2013 to 31st December 2013.Out of the 143 cases of plant poisoning, study population consisted of76 (53%)patients who consumed Oduku. Mean age of the population was 33.5 years (+/-SD 16.10). 43 patients (57.33%) were asymptomatic; among those with symptoms, 41 patients (54.67%). had nausea, 33 patients (44.00%) had vomiting, 7 patients (9.33%) had abdominal pain, 1 patient (1.33%) had palpitation and altered sensorium. Hypokalemia was found in 15 patients (19.74%) on admission, 7 patients (9.33%) after 24 hours and 8 patients (10.67%) after 48 hours. ECG changes observed were ST depression (23.68%), T inversion (23.68%) and u waves (17.11%). Mortality rate of Oduku poisoning found in this study was 2.63% (n=2) and expired patients showed persistent hypokalemia despite treatment. Oduku plant constitutes a major agent of DSH among the plant poisons in South India. Gastrointestinal, cardiovascular and neurological symptoms are common with oduku poisoning. Hypokalemia and ECG changes are seen, but mortality rate is low.
Keywords
Cleistanthus Collinus, Oduku Poisoning, Deliberate Self Harm, Hypokalemia, U Waves
To cite this article
Ramya Das N. K., Mary Grace N. C., Indira M., Jayachandran N. V., Clinical and Laboratory Profile of Patients Admitted with Cleistanthus Collinus Poisoning in a Tertiary Care Hospital, American Journal of Internal Medicine. Special Issue: Toxicology. Vol. 3, No. 6-1, 2015, pp. 14-17. doi: 10.11648/j.ajim.s.2015030601.14
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