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Evaluation of Health Related Quality of Life in Cancer Patients Receiving Chemotherapy
Science Journal of Public Health
Volume 5, Issue 5-1, October 2017, Pages: 1-7
Received: Jan. 11, 2017; Accepted: Jan. 18, 2017; Published: Feb. 14, 2017
Volume 5, Issue 5-1, October 2017, Pages: 1-7
Received: Jan. 11, 2017; Accepted: Jan. 18, 2017; Published: Feb. 14, 2017
Views 3659 Downloads 186
Authors
Abdelrahim Saad Shoulah, Department of Community Medicine, Faculty of Medicine, Benha University, Benha, Egypt
Mahmoud Ali Saleh, Department of Community Medicine, Faculty of Medicine, Benha University, Benha, Egypt
Shereen Mohamed Abdelwahab, Department of Community Medicine, Faculty of Medicine, Benha University, Benha, Egypt
Mona Ahmad Elawady, Department of Community Medicine, Faculty of Medicine, Benha University, Benha, Egypt
Eman Fadel Elsheikh, Department of Community Medicine, Faculty of Medicine, Benha University, Benha, Egypt
Abstract
Background: Cancer is considered as the second leading cause of death worldwide. Objectives: To evaluate health-related quality of life (HRQOL) among cancer patients receiving chemotherapy and to identify the most important determinants that affect them. Methods: This cross-sectional study included 190 cancer patients who have been received chemotherapy at the day care clinics in Nasser Institute Cancer Center (NICC). To address our subject, we analyzed HRQOL, as measured by the Functional Assessment of Cancer Therapy-General questionnaire (FACT-G), Arabic Version 4, and depicted the complex relations among physical, psychological, social, and cultural factors. Results: From cancer patients (190) [aged from 23 to 81 years (50.63±11.79)] 153 patients (80.53%) were females. FACT-G total score ranged from 21.2 to 87 (63.24±12.74) which is considered relatively poor (the physical and functional domains were more affected). HRQOL of the study group was not affected by gender, employment status, education level, smoking habits or marital status while it was negatively correlated with age, time since diagnosis of cancer, and disease stage. Patients’ HRQOL shown to be affected by the presence of many variables like low-performance status as evaluated by Eastern Cooperative Oncology Group (ECOG) scale, associated comorbidities, exposure to radiotherapy, history of surgery, and absence of menstrual status in female patients. A positive correlation was found between HRQOL and higher body mass index (BMI), and it was observed that the HRQOL of patients with higher perceived financial status was better. Conclusion: The HRQOL of cancer patients tended to be lower than the norms of the healthy people. Preplanned health programs should be designed to support early disease diagnosis, optimizing treatment choices, controlling of associated comorbidities, improving patients’ performance status as well as working on improving health insurance coverage.
Keywords
Cancer, Chemotherapy, Health Related Quality of Life
To cite this article
Abdelrahim Saad Shoulah,
Mahmoud Ali Saleh,
Shereen Mohamed Abdelwahab,
Mona Ahmad Elawady,
Eman Fadel Elsheikh,
Evaluation of Health Related Quality of Life in Cancer Patients Receiving Chemotherapy, Science Journal of Public Health. Special Issue: Malnutrition in Developing Countries.
Vol. 5, No. 5-1,
2017, pp. 1-7.
doi: 10.11648/j.sjph.s.2017050501.11
Copyright
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
[1]
Siegel R, Naishadham D, Jemal A. Cancer statistics 2012. CA Cancer J Clin. 2012 Jan-Feb; 62 (1): 10-29.
[2]
American Cancer Society. Global Cancer Facts & Figures 2nd Edition. Atlanta: American Cancer Society; 2011. Available at: http://oralcancerfoundation.org/wp-content/uploads/2016/03/acspc-027766.pdf, accessed on 6th Jan 2017.
[3]
Lianqi Liu, Lavinia Fiorentino, Michelle Rissling, Loki Natarajan, Barbara A. Parker, Joel E. Dimsdale, Paul J. Mills, Georgia Robins Sadler, Sonia Ancoli-Israel. Decreased Health-Related Quality of Life in Women with Breast Cancer is Associated with Poor Sleep. Behav Sleep Med. 2013 July; 11 (3): 189–206.
[4]
Priestman T. Cancer Chemotherapy in Clinical Practice. Second edition. Springer. 2012. DOI 10.1007/978-0-85729-727-3.
[5]
Pockaj BA, Degnim AC, Boughey JC, Gray RJ, McLaughlin SA, Dueck AC, Perez EA, Halyard MY, Frost MH, Cheville AL, Sloan JA. Quality of life after breast cancer surgery: What have we learned and where should we go next. J Surg Oncol. 2009 Jun 1; 99 (7): 447-455.
[6]
Klee MC, King MT, Machin D, Hansen HH. A clinical model for quality of life assessment in cancer patients receiving chemotherapy. Ann Oncol. 2000; 11 (1): 23-30.
[7]
Siddiqui F, Kachnic LA, Movsas B. Quality-of-life outcomes in oncology. Hematol Oncol Clin North Am. 2006 Feb; 20 (1): 165–185.
[8]
Cella D, Tulsky D, Gray G, Linn E, Bonomi A, Silberman M, Yellen SB, Winicour P, Brannon J. The Functional Assessment of Cancer Therapy Scale: development and validation of the general measure. J Clin Oncol 1993; 11 (3): 570-579.
[9]
Cella D, Hernandez L, Bonomi AE, Corona M, Vaquero M, Shiomoto G, Baez L. Spanish language translation and initial validation of the functional assessment of cancer therapy quality of life instrument. Med Care 1998 Sep; 36 (9): 1407-1418
[10]
Dapueto JJ, Servente L, Francolino C, Hahn EA. Determinants of quality of life in patients with cancer. Cancer. 2005 Mar 1; 103 (5): 1072-1081.
[11]
Ganz PA, Greendale GA, Petersen L, Kahn B, Bower JE. Breast cancer in younger women: reproductive and late health effects of treatment. J Clin Oncol. 2003 Nov 15; 21 (22): 4184-4193.
[12]
Wang SY, Hsu SH, Gross CP, Sanft T, Davidoff AJ, Ma X, Yu JB. Association between Time since Cancer Diagnosis and Health-Related Quality of Life: A Population-Level Analysis. Value Health. 2016 Jul-Aug; 19 (5): 631-638.
[13]
Wan G, Counte M, Cella D, Hernandez L, McGuire DB, Deasay S, Shiomoto G, Hahn EA. The impact of socio-cultural and clinical factors on health-related quality of life reports among Hispanic and African-American cancer patients. J Outcome Meas. 1999; 3 (3): 200–215.
[14]
kholoud A, Abdul-Monim B, Mohammed S, Mohammed A. Impact of Radiotherapy Treatment on Jordanian Cancer Patients Quality of Life and Fatigue. International Journal of Advanced Nursing Studies. 2014; 3 (1): 6-12.
[15]
Mei F, Amber D, Guth J, Charles M. Cleland, Caitlin E. Ryan, Kristen R. Weaver, Jeanna M. Qiu, Robin Kleinman, Joan Scagliola, Joseph J. Palamar, and Gail D’Eramo Melkus. Comorbidities and Quality of Life among Breast Cancer Survivors: A Prospective Study J Pers Med. 2015 Sep; 5 (3): 229–242.
[16]
Janda M, DiSipio T, Hurst C, Cella D and Newman B. The Queensland cancer risk study: general population norms for the functional assessment of cancer therapy–general (FACT-G). 2009 Jun; 18 (6): 606-614.
[17]
Lin LL, Brown JC, Segal S, Schmitz KH. Quality of life, body mass index, and physical activity among uterine cancer patients. Int J Gynecol Cancer. 2014 Jul; 24 (6): 1027-1032.
[18]
Laxmi K, Katherine E, Mary S, Anushree R, Maureen P, Jill PG and Clarisa RG. Quality of life in female cancer survivors: Is it related to ovarian reserve? Qual Life Res. 2014 Mar; 23 (2): 585–592.
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