Relationship between Body Mass Index and Bone Mineral Density in Saudi Women Above 40 Years with Vitamin D Deficiency
Science Journal of Public Health
Volume 2, Issue 6, November 2014, Pages: 601-604
Received: Nov. 16, 2014;
Accepted: Nov. 18, 2014;
Published: Nov. 21, 2014
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Anitha Oommen, Department of Anatomy, Northern Border University, P. O. Box 1321, Arar, Saudi Arabia
Ibrahim Hassan AlZahrani, Department of Pathology, King Abdul Aziz University, Jeddah, P. O. Box 80205, Saudi Arabia
Allahrakhyo S. Shoro, Arar Central Hospital, Arar, Saudi Arabia
Jamal Alruwaili, Department of Anatomy, Northern Border University, P. O. Box 1321, Arar, Saudi Arabia
Braa Aboalseel, Department of Anatomy, Northern Border University, P. O. Box 1321, Arar, Saudi Arabia
Low body mass index (BMI) causing low bone mineral density (BMD) has been reported in several articles. There are also contradictory data available which shows that obesity is associated with low bone mass. Vitamin D deficiency is a very common problem in Saudi women due to their lifestyle and culture. The present study was conducted to find out the relationship between body mass index and bone mineral density in Saudi women who have vitamin D deficiency. After the Vitamin D level assessment, the patients underwent Dual Energy X-ray Absorptiometry (DEXA) scan. Patients who had hormonal disorders, renal diseases and who were on immunosuppressive drugs were excluded from the study. Among the patients who had Vitamin D deficiency, 42.7 % had normal BMD while 57.3 % had low BMD. The BMD was low in 80% with normal BMI, 74.1% in overweight and 50% in obese patients. There was no statistically significant association between BMI and BMD (P>0.05) although there was a significant association between exercise and BMD (P<0.05) and age and BMD (P<0.05). The results indicate that bone loss and osteoporosis can occur in obese patients above 40 years of age, if they are not having sufficient exercise.
Ibrahim Hassan AlZahrani,
Allahrakhyo S. Shoro,
Relationship between Body Mass Index and Bone Mineral Density in Saudi Women Above 40 Years with Vitamin D Deficiency, Science Journal of Public Health.
Vol. 2, No. 6,
2014, pp. 601-604.
Morin S, Tsang J.F, et al., “Weight and body mass index predict bone mineral density and fractures in women aged 40 to 59 years”, Osteoporosis Int 2009; 20:363-370.
Guney E, Kisakol G, et al, “Effect of weight loss on metabolism: comparison of vertical banded gastroplasty and medical intervention”, Obes Surg. 2003; 13(3):383-388.
Kofi Asmaning, Elizabeth R, “The association between body mass index and osteoporosis in patients referred for a bone density examination”, Journal of women’s health, 2006; 15(9): 1028-1034.
Greco E.A, Fornari R, et al, “Is obesity protective for osteoporosis? Evaluation of bone mineral density in individuals with high body mass index”, Int J Clin Pract.2010; 64(6):817-820
Chubak J, Ulrich C.M, et al, “Effect of exercise on bone mineral density andlean mass in postmenopausal women”, Med Sci Sports Exerc. 2006; 38(7):1236-1244.
Stewart KJ, Bacher AC, et al, “Exercise effects on bone mineral density relationship to changes in fitness and fatness”, Am J Prev Med. 2005; 28(5): 453-460
Vieth R, ‘The role of Vitamin D in the prevention of osteoporosis”, Ann Med.2005; 37(4):278-285.
J Chris Gallagher, Adarsh J Sai, “Vitamin D insufficiency, deficiency and Bone health”, J ClinEndocrinolMetab, 2010; 95(6): 2630-2633.
Tarek Fawzy, Jayakumary M, et al, “Association between Body Mass Index and Bone Mineral Density in patients referred for dual energy X-ray Absorptiometry Scan in Ajman, UAE”, Journal of osteoporosis, 2011; Article ID 876309, 4 pages
Ben Sedrine W, Broers P, et al, “ Interest of a Prescreening Questionnaire to Reduce the Cost of Bone Densitometry”, OsteoporosInt, 2002;13:434-442.
Glen M.B, Ignac F, “The role of DXA bone density scans in the diagnosis and treatment of osteoporosis”, Postgrad Med J, 2007; 83: 509- 517.
Hussein R, Munira A, et al, “Updated recommendations for the diagnosis and management of osteoporosis”, Ann Saudi Med. 2011; 31(2):111-128.
Lan Juan Zhao, Yong- Jun Liu, et al, “Relationship of obesity with osteoporosis”, J ClinEndocrinolMetab, 2007; 92:1640-1646.
Kanis J.A, Johnell O, et al, “FRAXTM and the assessment of fracture probability in men and women from the UK, OsteoporosInt, 2008; 19: 385-397.
Jacobo W, Lois Y.M, et al, “Decreased bioavailability of vitamin D in obesity1-3”, Am J ClinNutr, 2000; 72: 690-693.
Jay J.C, “Effects of obesity on bone metabolism”, Journal of Orthopaedic Surgery and Research, 2011; 6:30.
Law MR, Hackshaw AK, “A meta-analysis of cigarette smoking, bone mineral density and risk of hip fracture: a recognition of a major effect”, BMJ, 1997; 315: 841-846.
Warensjo E, Liisa B, “Dietary calcium intake and risk of fracture and osteoporosis: prospective longitudinal cohort study”, BMJ, 2011; 342: d1473.