Factors Affecting Adherence to Treatment of HIV in Exposed Infants in Mumias Region, Western Kenya
Science Journal of Public Health
Volume 3, Issue 3, May 2015, Pages: 366-372
Received: Apr. 1, 2015;
Accepted: Apr. 14, 2015;
Published: Apr. 23, 2015
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Sophia Musenjeri, Institute of Tropical Medicine and Infectious Diseases (ITROMID) Nairobi, Kenya, Jomo Kenyatta University of Agriculture and Technology, Kenya Medical Research Institute, Nairobi, Kenya
Serah Mbatia, Institute of Tropical Medicine and Infectious Diseases (ITROMID) Nairobi, Kenya, Jomo Kenyatta University of Agriculture and Technology, Kenya Medical Research Institute, Nairobi, Kenya
Joseph Nganga, Jomo Kenyatta university of Agriculture and Technology, Nairobi, Kenya
Matilu Mwau, Consortium for National health research, Nairobi, Kenya
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Objective: To determine social-demographic and economic factors affecting adherence to treatment of HIV in exposed infants in Mumias region, Western Kenya. Methods: The study was a descriptive cross sectional study carried out among parents of HIV exposed infants in selected health facilities in western Kenya. Through random sampling, the study recruited three hundred and eighty four (384) parents aged between 15-66 years old. The parents who were recruited were seeking HIV testing, treatment and care for their infants. The laboratory procedure involved automated assay: Abbott Real-time HIV-1. Secondly, structured interviewer administered questionnaire was used to collect information from parentsof the affected infants. Data was analyzed using SPSS version 20. Results: 5.2% (20) of the participants tested positive while 94.8% (364) tested negative. Married participants were more likely to adhere to treatment (Odds ratio (OR) =1.062, 95%CI 0.628-1.796 P<0.05). Educated participants were more likely to attend their clinical appointments compared to the non-educated (0R=1.140, 95% C.I 0.949-1.369 P<0.05). Participants aged above 35 years old were more likely to adhere to treatment compared to those below 35 years old (OR=1.029, 95% C.I 0.985-1.074 P<0.05). Participants whose children tested negative at 6 weeks were more likely to adhere to treatment (OR=0.652, 95% C.I 0.185-2.305 P<0.05). Parentsunder the support of Community Health Workers (CHW) were more likely to adhere to treatment (OR=1.226, 95%C.I 0.419-3.581 P<0.05). Non-stigmatized mothers were more likely to adhere to treatment (OR=1.101, P<95% C.I 0.545-2.223). Conclusion: Adherence to treatment and care of HIV in exposed infants appears to be a significant challenge for HIV diagnostic and preventive services. To forestall the consequences, the stakeholders and government have to support the parents both financially and socially especially through public awareness campaigns to encourage them to adhere to treatment and care services.
Adherence HIV, Infants, Diagnosis, Stigma, CHW
To cite this article
Factors Affecting Adherence to Treatment of HIV in Exposed Infants in Mumias Region, Western Kenya, Science Journal of Public Health.
Vol. 3, No. 3,
2015, pp. 366-372.
NASCOP. National Guidelines for Antiretroviral Therapy in Kenya, 4th Edition. In. Nairobi, Kenya; 2011.
NASCOP Na. Kenya AIDS Epidemic update; 2012. In; 2012.
NASCOP. Kenya AIDS Indicator Survey ll-Final report. http://nascop.or.ke/library/3d/Preliminary%20Report%20for%20Kenya%20AIDS%20indicator%20survey%202012.pdf 2013:7-14.
NASCOP. Kenya AIDS progress report 2014. http://www.unaids.org/sites/default/files/country/documents/KEN_narrative_report_2014.pdf 2014.
Khamadi S. OV, Lihana R., Nabwera J., Hungu J., and Okoth F., . Rapid identification of infants for antiretroviral therapy in a resource poor setting: the Kenya experience. Journal of Tropical Pediatrics 2008,54:370-374.
Zijenah LS. HJ, Nathoo K Evaluation of the prototype Roche DNA amplification kit incor- 5 porating the new SSK145 and SKCC1B primers in detection of human immunodeficiency virus type 1 DNA in Zimbabwe. Journal of Clinical Microbiology 1999,37:3569–3570.
Cassol S.A. LN aST. Diagnosis of vertical HIV-1 transmission using the polymerase chain reaction and dried blood spot specimens. Journal of Acquired Immune Deficiency Syndrome 1992,113.
Liu L JH, and Cousens S. Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. lancet 2012,27:22-26.
NASCOP. Kenya HIV Drug resistance Country Report. In. Nairobi; 2011.
Creek T. TA SM. Early diagnosis of human immunodeficiency virus in infants using 105 polymerase chain reaction on dried blood spots in Botswana’s national program for prevention of mother-to-child transmission. Pediatrics Infecioust Diseases journal 2008,27:22-26.
Albert J aBIAs, sensitive, and specific detection of human immunodeficiency virus type 1 subtype B DNA in dried blood samples for diagnosis in infants in the field. . simple,sensitive, and specific detection of human immunodeficiency virus type 1 subtype B DNA in dried blood samples for diagnosis in infants in the field. Journal of Clinical Microbiogy. 2 2001,39:29-33.
Audu R A. SOB, Musa AZ Estimation of the rate of mother to child transmission of HIV in Nigeria. African Journal of Medical science 2006,35:121 to 124.
ALEX H. KRIST MD, and AMY CRAWFORD-FAUCHER. Management of Newborns Exposed to Maternal HIV Infection. American Academy of Family Physicians 2002,65::049-056,2061.
Galdas PM CF, and Marshall P. . Men and health help-seeking behaviour. journal of Adv NVPS 2005,49.
Omondi MP. An assessment of institutional factors affecting uptake of ARV prophylaxis amongst HIV positive pregnant women in Kakamega District. In: University of Nairobi; 2010. pp. 14.
N T. Sexual activity of out-of-school youth, and their knowledge and attitudes about STDs and HIV/AIDS in southern Ethiopia. Ethiopian Journal of Health Development. 1998,12:17-22.
Muchedzi A. CW KJ, Stranix-Chibanda L., Woelk G., Mbizvo E., Shetty A K. Factors associated with access to HIV care and treatment in a prevention of mother to child transmission programme in urban Zimbabwe. Journal of the International AIDS Society 2010,13.
World Health Organization JUNPoHA UNCsF. Towards Universal Access: Scaling up Priority HIV/AIDS Interventions in the Health Sector. In. http://www.unaids.org/sites/default/files/country/documents/KEN_narrative_report_2014.pdf.; 2011.
Newell ML. CH CBM, Rollins N., Gaillard P., Dabis F. Ghent International AIDS Society (IAS) Working Group on HIV Infection in Women and Children. Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: a pooled analysis. lancet kenya 2004,364:1236-1243.
Programme NAaSC. Kenya AIDS Indicator Survey 2012: Preliminary Report, Nairobi, Kenya. In: Ministry of Health; 2013.