Epidemiological Profile of Thrombophilia in Marrakech (Morocco): About 200 Cases
American Journal of Laboratory Medicine
Volume 4, Issue 5, September 2019, Pages: 79-86
Received: Jul. 31, 2019; Accepted: Aug. 30, 2019; Published: Sep. 19, 2019
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Ilham Karrati, Haematology Laboratory of Avicenne Military Hospital, University Hospital Mohamed VI, Marrakech, Morocco
Hanane Mouhib, Haematology Laboratory of Avicenne Military Hospital, University Hospital Mohamed VI, Marrakech, Morocco
Hicham Yahyaoui, Haematology Laboratory of Avicenne Military Hospital, University Hospital Mohamed VI, Marrakech, Morocco
Radia Amaddah, Haematology Laboratory of Avicenne Military Hospital, University Hospital Mohamed VI, Marrakech, Morocco
Mustapha Aitameur, Haematology Laboratory of Avicenne Military Hospital, University Hospital Mohamed VI, Marrakech, Morocco
Mohamed Chakour, Haematology Laboratory of Avicenne Military Hospital, University Hospital Mohamed VI, Marrakech, Morocco
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Thrombophilia is a situation characterized by an increased tendency to thrombosis. The main objective of this work is to report on the experience of the Haematology Laboratory of the Avicenne Military Hospital of Marrakech, through a retrospective descriptive study carried out over a period of 9 years, on 200 requests for a thrombophilia check-up; and secondly, to discuss its indications and interest in the etiological diagnosis of unexplained thrombosis in the light of the latest recommendations. The thrombogenic risk factor most commonly found in our study was PS deficiency, in contrast to the predominance of Factor V mutation in Western countries, hence the importance of emphasizing that in clinical practice, the first-line thrombophilia assessment should always combine, in accordance with the latest recommendations: inhibitor deficiencies, F V and F II mutations, antiphospholipid antibodies and possibly F VIII determination.
Thrombophilia Assessment, Protein C, Protein S, Antithrombin, Factor V mutation, Factor II Mutation
To cite this article
Ilham Karrati, Hanane Mouhib, Hicham Yahyaoui, Radia Amaddah, Mustapha Aitameur, Mohamed Chakour, Epidemiological Profile of Thrombophilia in Marrakech (Morocco): About 200 Cases, American Journal of Laboratory Medicine. Vol. 4, No. 5, 2019, pp. 79-86. doi: 10.11648/j.ajlm.20190405.11
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