Antibiotic Susceptibility of Staphylococcus aureus Isolates from Clinical Samples in Aminu Kano Teaching Hospital, Kano, Nigeria
American Journal of Laboratory Medicine
Volume 2, Issue 4, July 2017, Pages: 41-44
Received: Apr. 13, 2017;
Accepted: Aug. 22, 2017;
Published: Sep. 12, 2017
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Abdulhadi Sale Kumurya, Department of Medical Laboratory Science, Faculty of Allied Health sciences, Bayero University, Kano, Nigeria
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Bacterial colonies can differ greatly in their morphologies. These differences can help us in identifying different species of bacteria. The clinical isolates of Staphylococcus aureus are subjected to antibiotic susceptibility, to observe the susceptibility of the isolates against some conventional antibiotics. One hundred and ten (110) pathogenic Staphylococcus aureus strains were used in this study. Antibiotic susceptibility tests were carried out by disc agar diffusion test. Staphylococcus aureus ATCC 25923 was used as a reference control organism. From this study, males were more infected than females, having 60 (61.8%) and 42 (38.2%) respectively. The age group with the highest number of isolates was (0-10) years while blood culture had the highest frequency of Staphylococcus aureus isolates with a frequency of 42 (38.1%). The sensitivity pattern of Staphylococcus aureus to the following antibiotics; clindamycin, ciprofloxacin, erythromycin, cloxacillin, cephalexin, co-trimoxazole, tetracycline and amoxyclav were 85 (77.3%), 72 (65.5%), 66 (60%), 51 (46.4%), 46 (41.8%), 43 (39.1%), 43 (39.1%) and 33 (30%) respectively. This study showed that Clindamycin, Ciprofloxacin and Erythromycin were the most active antibiotics against Staphylococcus aureus. Thus it is believed that these antibiotics should be used in the treatment of Staphylococcus aureus infections in this region. The study provided epidemiologic data and there is the need for consistent on-going antimicrobial resistance surveillance for important and commonly isolated clinically significant pathogens of staphylococcal species to form the basis for developing and implementing measures that can reduce the burden of antimicrobial resistance and prevent a probable impending public health problem.
Staphylococcus aureus, Antibiogram, Clinical Samples, Treatment
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Abdulhadi Sale Kumurya,
Antibiotic Susceptibility of Staphylococcus aureus Isolates from Clinical Samples in Aminu Kano Teaching Hospital, Kano, Nigeria, American Journal of Laboratory Medicine.
Vol. 2, No. 4,
2017, pp. 41-44.
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Cheesbrough, M. (2010). District Laboratory Practice in Tropical Countries part two, New York, Cambridge University Press U. S. pp. 64-67.
Cookson, B. D. and Phillips, I. (1998). Epidemic MRSA. Journal of Antimicrobial chemotherapy. 21:57-65.
Deurenberg, R. H. and Stobberingh, E. E. (2008). The evolution of Staphylococcus aureus Infection. Genetics and Evolution. 8(6):747-763.
Emmanuel, O. N. and Magaji, S. N. (2011). Antibiotic susceptibility pattern of Staphylococcus aureus from Clinical Isolates in tertiary insititution in northern Nigeria. Pan African Medical Journal. 8:4.
Isenberg, H. D. (1998). Agar screening test to detectoxacillin (methicillin) resistant Staphylococcus Spp. In: Essential procedures for clinical microbiology. 4:232-234.
Kloos, W. E. (1998). Staphylococcus. In: Topley and Wilson’s Microbiology and Microbial Infections, London: Edward Arnold.; Vol. 2(9th edn):602–611.
Kumurya, A. S. and Ado Z. G. (2015). Detection of clindamycin resistance among methicillin-resistant Staphylococcus aureus isolates in Kano, Nigeria. Access journal of microbiology. 1(1): 1-7.
Montefiore, D., Rotimi, V. O., Adeymi-Doro, F. A. B. (1989). The problem of bacterial resistance to antibiotics among strains isolated from hospital patients in Lagos and Ibadan, Nigeria. J Antimicrob Chemother. 23(4):641–51.
National Committee for Clinical Laboratory Standards (2006). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. 6th ed. Approved standard, M7-A6. Wayne, Pennsylvania.
Ndip, R. N., Ebah, L. M. E. and Onile, B. A. (1997). Antibiogram of Staphylococcus aureus from clinical Syndromes in Ilorin, Nigeria. Journal of Medical Laboratry Science. 6:24-26.
Nneoma, C. J. S. and Walter, C. J. (2013). Conventional and Rapid Methods for Identification of Staphylococcus aureus from Clinical Specimens. American Journal of Biomedical and Life Sciences. 1(3):41-43.
Paul, M. O., Aderibie, D. A., Sule, C. Z. (1982). Antimicrobial sensitivity patterns of hospital and non hospital strains of Staphylococcus aureus isolated from nasal carriers. J Hyg Camb.89:253–260.
Skinner, D. and Keefer, C. S. (1941). Significance of bacteremia caused by Staphylococcus aureus. Archive of Internal Medicine. 68:851-875.
Subhankari, P. C., Santanu, K. M. and Somenath, R. (2011). Asian Pac J Trop Biomed. 1(3): 212–216. doi: 10.1016/S2221-1691(11)60029-4.