Please enter verification code
Application of Anterior Segment Optical Coherence Tomography in Refractive Surgery
International Journal of Ophthalmology & Visual Science
Volume 5, Issue 2, June 2020, Pages: 41-46
Received: Feb. 21, 2020; Accepted: Mar. 4, 2020; Published: Mar. 17, 2020
Views 485      Downloads 144
Peng Jiao, Department of Medical College, Hunan Provincial People’s Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China
Wang Hua, Center for Ophthalmic Optics, Hunan Provincial People’s Hospital, Changsha, China
Article Tools
Follow on us
With the development of modern medical technology, the accuracy and safety of refractive surgery in ophthalmology have been constantly improved. Many new examination methods have been applied in research and clinical practice, and anterior segment optical coherence tomography (AS-OCT) is a new non-contact non-invasive optical image diagnosis technology, which can be used to measure the biological structure of anterior segment. AS-OCT is widely used in the clinical diagnosis and treatment of corneal diseases, cataracts, glaucoma and other specialties due to its advantages of fast scanning speed, deep layer, high penetration rate and high resolution. In addition, AS-OCT can also obtain: corneal thickness, corneal epithelial thickness map, corneal topographic map, anterior chamber depth (ACD), white to white (WTW), crystal arch height (LV), Angle width of the anterior chamber, etc., so it is especially suitable for the pre-operative screening, design of operation scheme and safety evaluation after the operation of auxiliary ophthalmic refractive surgery (including corneal refractive surgery and intraocular refractive surgery). At present, corneal refractive surgery mainly includes excimer laser in-situ keratomileusis (LASIK), femtosecond laser-assisted LASIK (FS-LASIK), femtosecond laser stromal lens removal for small incision (SMILE), and transepithelial laser keratoplasty (T-PRK), and ICL implantation is the main method of intraocular refractive surgery. This article will review the clinical application of AS-OCT in corneal refractive surgery and intraocular refractive surgery, and provide reference for clinical practice.
AS-OCT, Keratorefractive Surgery, Intraocular Refractive Surgery, ICL Implantation
To cite this article
Peng Jiao, Wang Hua, Application of Anterior Segment Optical Coherence Tomography in Refractive Surgery, International Journal of Ophthalmology & Visual Science. Vol. 5, No. 2, 2020, pp. 41-46. doi: 10.11648/j.ijovs.20200502.11
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Shao yi. Application of optical coherence tomography angiography (OCTA) in clinical ophthalmology. New progress in ophthalmology 2017; 37 (09): 801-805.
Hwang ES, Schallhorn JM, Randleman JB. Utility of Regional Epithelial Thickness Measurements in Corneal Evaluations. Surv Ophthalmol 2019.
Lu NJ, Chen D, Cui LL, et al. Repeatability of Cornea and Sublayer Thickness Measurements Using Optical Coherence Tomography in Corneas of Anomalous Refractive Status. J Refract Surg 2019; 35 (9): 600-605.
Xu Benjamin Y, Penteado Rafaella C, Weinreb Robert N. Diurnal Variation of Optical Coherence Tomography Measurements of Static and Dynamic Anterior Segment Parameters. Journal of glaucoma 2018; 27 (1): 16-21.
Ong Hon Shing, Farook Mohamed, Tan Benjamin Boon Chuan, et al. Corneal Ectasia Risk And Percentage Tissue Altered In Myopic Patients Presenting For Refractive Surgery. Clinical ophthalmology (Auckland, N. Z.) 2019; 13: 2003-2015.
Tekce A, Gulmez M. Corneal sublayer thickness in patients with pseudoexfoliation syndrome evaluated by anterior segment optical coherence tomography. Int Ophthalmol 2019.
Fang chengbo, liao rongfeng, zhu qiang, et al. Analysis of the causes of corneal refractive surgery without excimer laser. Acta ophthalmologica sinica 2018; 33 (01): 15-19.
Chen yuelan. Observation on RGP correction effect of keratoconus conus secondary to corneal refractive surgery. Medical theory and practice 2014; 27 (18): 2405-2407.
Ayala M, Strandås R. Accuracy of optical coherence tomography (OCT) in pachymetry for glaucoma patients. BMC Ophthalmol 2015; 15: 124.
Li dong, Jia zhijie, Zhang haining, et al. Comparison of Pentacam and anterior articular OCT in the measurement of central corneal thickness. Electronic journal of clinical medicine literature 2019; 6 (30): 85-86.
Desmond T, Arthur P, Watt K. Comparison of central corneal thickness measurements by ultrasound pachymetry and 2 new devices, Tonoref III and RS-3000. Int Ophthalmol 2019; 39 (4): 917-923.
Duan yu-hui, Mi sheng-jian, Li zhong-ji, et al. Comparison of Sirius, Oculyzer, as-oct and a-ultrasound in measuring the thinnest point thickness of the cornea in myopia patients. International journal of ophthalmology 2019; 19 (08): 1377-1380.
Sin S, Simpson TL. The repeatability of corneal and corneal epithelial thickness measurements using optical coherence tomography. Optom Vis Sci 2006; 83 (8): 360-365.
Reinstein DZ, Archer TJ, Gobbe M. Change in epithelial thickness profile 24 hours and longitudinally for 1 year after myopic LASIK: three-dimensional display with Artemis very high-frequency digital ultrasound. Journal of Refractive Surgery 2012; 28 (3): 195-201.
Reinstein DZ, Srivannaboon S, Gobbe M, et al. Epithelial thickness profile changes induced by myopic LASIK as measured by Artemis very high-frequency digital ultrasound. J Refract Surg 2009; 25 (5): 444-50.
Ivarsen A, Fledelius W, Hjortdal JQ. Three-year changes in epithelial and stromal thickness after PRK or LASIK for high myopia. Invest Ophthalmol Vis Sci 2009; 50 (5): 2061-2066.
Ryu IH, Kim BJ, Lee JH, et al. Comparison of Corneal Epithelial Remodeling After Femtosecond Laser-Assisted LASIK and Small Incision Lenticule Extraction (SMILE). Refract Surg 2017; 33 (4): 250-256.
Salomão MQ, Hofling-Lima AL, Lopes BT, et al. Role of the corneal epithelium measurements in keratorefractive surgery. Curr Opin Ophthalmol 2017; 28 (4): 326-336.
Miu ling, Hu yiqing, Zhu huang, et al. Progress in surgical treatment of refractive regression after corneal refractive surgery. Advances in modern biomedicine 2019; 19 (01): 180-184.
Sanchis-Gimeno JA, Herrera M, Sanchez-del-Campo F, et al. Differences in ocular dimensions between normal and dry eyes. Surg Radiol Anat 2006; 28 (3): 267-270.
Huang ting, Qin yu, Qu bo. Comparison of central corneal thickness measured by AS-OCT, Lenstar and UBM. Journal of China medical university 2018; 47 (02): 123-127.
Deng jing, Meng huan, Li yingjun, et al. Application and research progress of corneal topography in excimer laser corneal refractive surgery. Chinese community physician 2014; 30 (36): 12-13.
Randleman JB, Woodward M, Lynn, MJ, et al. Risk Assessment for Ectasia after Corneal Refractive Surgery. Ophthalmology 2007; 115 (1): 37-50.
Tan anzu, Yu man, Chen xuan, et al. Application of deep learning in early diagnosis of keratoconus. Chinese journal of medical devices 2019; 43 (02): 83-85.
Schröder S, Mäurer S, Eppig T, et al. Comparison of Corneal Tomography: Repeatability, Precision, Misalignment, Mean Elevation, and Mean Pachymetry. Curr Eye Res 2018; 43 (6): 709-716.
Li Y, Meisler DM, Tang M, et al. Keratoconus diagnosis with optical coherence tomography pachymetry mapping. Ophthalmology 2008; 115 (12): 2159-66.
Ambrósio R, Tervo T, Wilson SE. LASIK-associated dry eye and neurotrophic epitheliopathy: pathophysiology and strategies for prevention and treatment. J Refract Surg 2008; 24 (4): 396-407.
Raj A, Dhasmana R, Nagpal RC. Anterior segment optical coherence tomography for tear meniscus evaluation and its correlation with other tear variables in healthy individuals. Clin Diagn Res 2016; 10 (5): Nc01-04.
Yin Hongzhi. ICL four instruments and gauges measured preoperative corneal diameter. International journal of ophthalmology 2019, 19 (04): 701-703.
Jing Zhang, Hui-Hui Luo, Jing Zhuang, et al. Comparison of anterior section parameters using anterior segment optical coherence tomography and ultrasound biomicroscopy in myopic patients after ICL implantation. International Journal of Ophthalmology 2016; 9 (01): 58-62.
Zhou SY, Wang CX, Cai XY, et al. Optical coherence tomography and ultrasound biomicroscopy imaging of opaque corneas. Cornea 2013; 32 (4): e25-30.
Zeng wenhui, Wang hua. Factors influencing the arch height after posterior chamber intraocular lens implantation. International journal of ophthalmology 2018; 18 (03): 457-460.
Alfonso JF, Fernández-Vega L, Lisa C, et al. Long-term evaluation of the central vault after phakic Collamer® lens (ICL) implantation using OCT. Graefes Arch Clin Exp Ophthalmol 2012; 250 (12): 1807-12.
Chung TY, Park SC, Lee MO, et al. Changes in iridocorneal angle structure and trabecular pigmentation with STAAR implantable collamer lens during 2 years. J Refract Surg 2009; 25 (3): 251-8.
Chen Xin Yang. High myopia posterior chamber lens eye sight after the implantation of introcular lens section anatomy and preliminary study of the scattering light. Fudan university 2013.
Chen qing, Yu peng, Zhao yali, Guo xiaomei. Allegro Oculyzer anterior segment diagnostic system evaluation of intraocular segment parameter changes and correlation analysis of intraocular pressure after ICL. International journal of ophthalmology 2016; 16 (08): 1515-1518.
Wan T, Yin H, Yang Y, et al. Comparative study of anterior segment measurements using 3 different instruments in myopic patients after ICL implantation. BMC Ophthalmol 2019; 19 (1): 182.
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
Tel: (001)347-983-5186