Optical Coherence Tomography Angiography to Detect and Differentiate Ischemic Optic Neuropathy from Papilledema - Systematic Review
International Journal of Ophthalmology & Visual Science
Volume 4, Issue 4, December 2019, Pages: 66-70
Received: Aug. 1, 2019;
Accepted: Sep. 25, 2019;
Published: Oct. 10, 2019
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Manuel Augusto Pereira Vilela, Medical School, Federal University of Health Sciences, Porto Alegre, Brazil; Ivo Corrêa-Meyer Institute, Porto Alegre, Brazil
Carina Graziottin Colossi, Ivo Corrêa-Meyer Institute, Porto Alegre, Brazil
Background: Optic disc is a region with a complex vascular stratification, with components from the posterior ciliary arteries and central retinal artery. Nonarteritic anterior ischemic optic neuropathy (NA-AION) and papilledema can produce disc edema and visual fields defects. Optical coherence tomography angiography (OCTA) can aid in the rapid differentiation of cases when signals overlap. Objective: The purpose of this systematic review is to discuss the current information concerning the signs in OCTA that eventually could help to differentiate these situations and analyze the best diagnostic evidence. Methods: A systematic search was conducted in the MEDLINE ("Medical Literature Analysis and Retrieval System Online") via Pubmed; Embase, Scopus, Web of Science, Google Scholar, BVS databases, in addition to a manual search on studies published, from inception until July 2019, with no language restriction. Results: Of the 20935 articles identified, eleven were included. Different methodologies, sample characteristics, types of equipment, potential artifacts, segmentation errors were the main arguments against formal meta-analysis. Conclusion: The main differentiation of papilledema from NA-AION is the vascular dropout. Density values in both retina and optic nerve head images were significantly lower in NA-AION. These vascular changes appears to precede detectable structural or visual field damage.
Manuel Augusto Pereira Vilela,
Carina Graziottin Colossi,
Optical Coherence Tomography Angiography to Detect and Differentiate Ischemic Optic Neuropathy from Papilledema - Systematic Review, International Journal of Ophthalmology & Visual Science.
Vol. 4, No. 4,
2019, pp. 66-70.
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
https://www.ncbi.nlm.nih.gov/pubmed/advanced. Accessed 15/july/2019
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