New Prediction Method of the Certain Type of Secondary Cataract
International Journal of Ophthalmology & Visual Science
Volume 2, Issue 4, November 2017, Pages: 120-124
Received: Sep. 8, 2017; Accepted: Sep. 25, 2017; Published: Nov. 5, 2017
Views 1741      Downloads 108
Nadezhda Vitalievna Korsakova, Medicine Department, Chuvash State University, Cheboksary, Russia
Article Tools
Follow on us
The aim of the research was to investigate the ophthalmologic status and to investigate the influence of dominating part of vegetative nervous system, following the different types of senile and secondary cataract formation in human. Thus, the domination а sympathetic nervous system and correlated systemic dystrophic changes of the tissues in patients with cortical and secondary proliferative cataract have been found for the first time. Moreover, patients with nuclear and secondary fibrous cataract had the domination of parasympathetic nervous system and another character of dystrophic changes. Therefore, the dominating part of vegetative nervous system can be offered as an available clinical marker of character of neurodystrophic process occurring in an eye. The revealed set of changes in the lens with its pathological aging includes violation of certain vagosympathetic balance of the autonomic nervous system and its post-operative complications development following even after a successful surgical treatment of age-related cataract – secondary cataract. The results allow for the first time to put forward a new view of the secondary cataract pathogenesis.
Secondary Cataract, Age-Related Cataract, Pathogenesis, Autonomic Nervous System, Prediction, Marker
To cite this article
Nadezhda Vitalievna Korsakova, New Prediction Method of the Certain Type of Secondary Cataract, International Journal of Ophthalmology & Visual Science. Vol. 2, No. 4, 2017, pp. 120-124. doi: 10.11648/j.ijovs.20170204.17
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
C. M. Hernandez (2010). Cataracts: Causes, Symptoms, and Surgery. New York, USA, ISBN 978-1-61668-955-1.
G. L. Kanthan et al. (2008). Ten-Year Incidence of Age-Related Cataract and Cataract Surgery in an Older Australian Population. The Blue Mountains Eye Study. Ophthalmology, 115:808-814.
E. V. Malcev and K. P. Pavluchenko (2002). Biological Features and Diseases of Lens. Odessa, Ukraine. ISBN 966-549-716-2.
N. V. Korsakova (2012). Modern Data about Age-Related Cataract Pathogenesis in Humans. New York, USA. ISBN 978-1-62081-823-7.
N. V. Korsakova et al. (2010). Discussing the Problem of Age-Related Cataract Pathogenesis in Human: Morphological and Immunohistochemical Aspects. In: C. M. Hernandez. Cataracts: Causes, Symptoms, and Surgery. Nova Publishers, New York, USA, pp 159-173.
L. Fontana et al. (2017). Cataract Surgery in Patients with Pseudoexfoliation Syndrome: Current Updates. Clin Ophthalmol., 11:1377-1383.
O. Sveinsson (1993). The Ultrastructure of Elschnig's Pearls in a Pseudophakic Eye. Acta Ophthalmol (Copenh), 71:95-98.
C. D. Freel et al. (2002). Fourier Analysis of Cytoplasmic Texture in Nuclear Fiber Cells from Transparent and Cataractous Human and Animal Lenses. Exp Eye Res, 74:689-702.
C. D. Freel et al. (2003). Ultrastructural Characterization and Fourier Analysis of Fiber Cell Cytoplasm in the Hyperbaric Oxygen Treated Guinea Pig Lens Opacification Model. Exp Eye Res, 76:405-415.
N. V. Korsakova et al. (2013). Immune Reactivity of Human Lens Structures in Norm, Age-Related Cortical and Secondary Opacification. Morfologiia, 143:28-31.
M. Gosak et al. (2015). The Analysis of Intracellular and Intercellular Calcium Signaling in Human Anterior Lens Capsule Epithelial Cells with Regard to Different Types and Stages of the Cataract. PLoS One, 10(12):e0143781.
S. Ju. Efremona et al. (2013). Secondary Cataract in Humans: Neuromediators profile of the Lens Epithelium Cells. Advances in Current Natural Sciences, 9:33-34.
N. V. Korsakova (2017). New Fluorescent-Histochemical and Immuno-Histochemical Aspects of Secondary Cataract Pathogenesis in Humans. International Journal of Photochemistry and Photobiology, 2(5):121-128.
N. V. Korsakova et al. (2012). Morphological Basis of Desympathization of the Eye as a New Means of Experimental Modeling of Cataract. Neuroscience and Behavioral Physiology, 42:1024-1028.
A. Synder et al. (2002). A Study of Human Lens Epithelial Cells by Light and Electron Microscopy and by Immunohistochemistry in Different Types of Cataracts. Klin Oczna, 104:369-373.
S. Saika et al. (2013). Response of Lens Epithelial Cells to Injury: Role of Lumican in Epithelial Mesenchymal Transition. Invest Ophthalmol Vis Sci, 44:2094-2102.
Z. Wei et al. (2017). Reduced Glutathione Level Promotes Epithelial-Mesenchymal Transition in Lens Epithelial Cells via a Wnt/β-catenin-mediated Pathway: Relevance for Cataract Therapy. Am J Pathol., pii: S0002-9440(17)30578-3.
A. M. Kvetnoy (2002). Neuroimmunoendocrinology – Chemical Community of Regulatory Systems. In: Materials of the International Science-Practical School-Conference ‘Cytokines. Influence. Immunity’. S.-Pb., pp 55-56.
N. V. Korsakova (2016). The Type of Age-Related Cataract as a Marker of Socially Significant Diseases. Advances of Gerontology, 6:44-46.
V. N. Shvalev et al. (2003). Transformation of Sympathetic-Adrenal System in Elderly and Senile Age as a Risk Factor of Cardiovascular Diseases. Kazan Medical Journal, 6:401-408.
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
Tel: (001)347-983-5186