Screening of Antioxidant and Antimicrobial Properties of the Syzygium jambos L.
American Journal of BioScience
Volume 3, Issue 2-1, April 2015, Pages: 23-26
Received: Mar. 16, 2015; Accepted: Mar. 16, 2015; Published: Apr. 23, 2015
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Authors
Mst. Marium Begum, Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
Majidul Haque, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
Md. Reyad-ul-Ferdous, Department of Pharmaceutical Sciences, North South University, Dhaka-1229, Bangladesh
Moynul Hasan, Department of Pharmacy, Dhaka International University, Dhaka-1213, Bangladesh
Hasan Tarek, Department of Pharmacy, Dhaka International University, Dhaka-1213, Bangladesh
Md. Noor-A-Alam, Department of Pharmacy, Dhaka International University, Dhaka-1213, Bangladesh
Md. Belal Hossain, Department of Pharmacy, Dhaka International University, Dhaka-1213, Bangladesh
Md. Nazir Uddin, Department of Pharmacy, Dhaka International University, Dhaka-1213, Bangladesh
Taslima Begum, Department of Pharmacy, Primeasia University, Dhaka-1213, Bangladesh
Choudhury Mahmood Hasan, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
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Abstract
Syzygium jambos (L.) Alstone belonging to the Myrtaceae family have been investigated for evaluation of their biological activities namely antioxidant and antimicrobial activity. The n-hexane, carbon tetrachloride, chloroform, aqueous soluble fractions of methanolic extract as well as crude methanolic extract of stem barks of Syzygium jambos were evaluated for their free radical scavenging activity. The methanolic extract and aqueous soluble fractions of stem barks of Syzygium jambos exhibited significant antioxidant activity with the IC50 value of 36.36 mg/ml and 44.744µg/ml respectively whereas chloroform, carbon tetrachloride and hexane soluble fraction of stem barks exhibited mild antioxidant activity with the IC50 value 191.018, 257.102, 414.79 mg/ml respectively. The crude extract, along with n-hexane, carbon tetrachloride and chloroform partitionates of the crude extract of Syzygium jambos were screened for their antimicrobial activity against a wide range of both gram-positive and gram-negative bacteria by the disc diffusion method. The results obtained were compared with that of a standard antibiotic, ciprofloxacin. All the fractions of Syzygium jambos exhibited mild activity against most of the test organism.
Keywords
Syzygium jambos, Medicinal Plant, Identification, Anti-oxidant, Antimicrobial Activity
To cite this article
Mst. Marium Begum, Majidul Haque, Md. Reyad-ul-Ferdous, Moynul Hasan, Hasan Tarek, Md. Noor-A-Alam, Md. Belal Hossain, Md. Nazir Uddin, Taslima Begum, Choudhury Mahmood Hasan, Screening of Antioxidant and Antimicrobial Properties of the Syzygium jambos L., American Journal of BioScience. Special Issue:Pharmacological and Phytochemicals Investigation. Vol. 3, No. 2-1, 2015, pp. 23-26. doi: 10.11648/j.ajbio.s.2015030201.15
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