Effect of Astaxanthin Supplementation on Antioxidant Capacity, Blood Lactate and Blood Uric Acid Metabolism in Human Recovery Stage After Exercise
Advances in Bioscience and Bioengineering
Volume 7, Issue 4, December 2019, Pages: 60-63
Received: Sep. 2, 2019;
Accepted: Sep. 23, 2019;
Published: Oct. 9, 2019
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Lijun Wu, Department of Human Kinesiology, Physical Education of Shanxi University, Taiyuan, China
Zhuo Sun, Department of Human Kinesiology, Physical Education of Shanxi University, Taiyuan, China
Jing Zhao, Department of Human Kinesiology, Physical Education of Shanxi University, Taiyuan, China
Xinming Guo, Department of Physical Education, Taiyuan Normal College, Taiyuan, China
Jie Wang, Department of Human Kinesiology, Physical Education of Shanxi University, Taiyuan, China
To study the effects of astaxanthin supplementation on serum antioxidant capacity, blood lactic acid and blood uric acid metabolism of human body in the 1h recovery period after acute high-intensity exercise. Sixteen male students grade 2016 from Physical Education Institution (age: 19.13±2.52, height: 179±4.21cm and weight 68.23±7.81kg) were randomly divided into two groups: group A (experimental) and B (control). Group A was given astaxanthin for 28 days at a moderate dose (12 mg/d) and placebo for 28 days at group B. 4 weeks later, all subjects underwent exercise on power bike. The antioxidant capacity and blood uric acid and the content of blood lactic acid was assayed using anti-oxidation Kit (FORD), blood lactic acid Kit (LACTIC ACID), blood uric acid Kit (URIC ACID). Results: 1) One hour after exercise, the antioxidant capacity in both A and B obviously increased without exception and the value of group A was obviously higher than B. The blood lactic acid in both groups dramatically declined and the value of group A was obviously lower than B. The blood uric acid rised in both groups and the value of A was obviously lower than B. Conclusions: Pre-supplement of astaxanthin can accelerate the recovery of antioxidant capacity, accelerate the clearance of blood lactate and delay the increase of blood uric acid in the body within 1 hour after exercise.
Effect of Astaxanthin Supplementation on Antioxidant Capacity, Blood Lactate and Blood Uric Acid Metabolism in Human Recovery Stage After Exercise, Advances in Bioscience and Bioengineering.
Vol. 7, No. 4,
2019, pp. 60-63.
Bigarella, C. L., Liang R., Ghaffar, S. (2014.) Stem cells and the impact of ROS signaling. Development. 141 (22): 4206-4218.
Andersent, L. P., Holck, S., Kupcinskas, L., Kiudelis, G., Jonaitis, L., Janciauskas, D., Permin, Wadstr, M. T. (2013). Gastric inflammatory markers and interleukins in patients with functional dyspepsia treated with astaxanthin. Pathogens & Disease. 50 (2): 244-248.
HÖhn, A., KÖnig, J., Grune, T. (2013). Protein oxidation in aging and the removal of oxidized proteins. Journal of Proteomics. 92, 132-159.
Ambati, R. R., Siew, M. P., Ravi, S. (2014) Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications—A Review. Marine Drugs 12 (1): 128-152.
Polotow, T. G., Vardaris, C. V., Mihaliuc, A. R., Gonçalves, M. S., Pereira, Ganini., Barros, M. P. (2014) Astaxanthin Supplementation Delays Physical Exhaustion and Prevents Redox Imbalances in Plasma and Soleus Muscles of Wistar Rats. Nutrients. 6 (12): 5819-5838.
Fumio, S., TakayaA, O., Mutsuki, I. (2015). Effects of Daily Astaxanthin and L-carnitine Supplementation for Exercise Induced Muscle Damage in Training Thoroughbred Horses. Journal of Equine Veterinary Science. 35 (10): 836–842.
Sophia, Z. L., Amir, S. A., Matthew, D. Campbell., Kevin, K., Shankland, E. G., Baback, R., David, J. M., Kevin, E. C. (2018). Building strength, endurance, and mobility using an astaxanthin formulation with functional training in elderly. J Cachexia Sarcopenia Muscle. 9 (5): 826–833.
Ayano, I., Yuriko, O., Naoki, T., Shinobu, S., Kiyotaka, N., Teruo, M., Fumitaka, U. (2018). Effects of Dietary Supplementation of Astaxanthin and Sesamin on Daily Fatigue: A Randomized, Double-Blind, Placebo -Controlled, Two-Way Crossover Study. Nutrients. 10 (3): 281.
Maki, T., Wataru, A., Hitomi, T., Yuko, T., Sayori, W., Akane, H. (2019). Effect of dietary antioxidant-rich foods combined with aerobic training on energy metabolism in healthy young men. J Clin Biochem Nutr. 64 (1): 79–85.
Wu Lijun, Guo Xinming, Zhang Junfeng. (2008). Effect of lycopene and exercise on the metabolism of free radicals in human serum. sports science. 28 (2): 47-53.
Lijun Wu, Zhuo Sun, An’ping Chen, Xinming Guo, Jie Wang. (2018). Effect of astaxanthin and exercise on antioxidant capacity of human body, blood lactic acid and blood uric acid metabolism. Science & Sports. doi.org/10.1016/j.scispo.2018.12.008.
Katrin, P., Michael, R., Katrin, S., Kathrin, R. S., Marina, K. (2015). Lactic acid delays the inflammatory response of human monocytes. Biochemical and Biophysical Research Communications. 457: 412-418.
Yuichiro Nishida, Minko Iyadomi, Yasuki Higai, Hiroaki Tanaka, Megumi Hara, Keitaro Tanka. (2011). Influence of Physical Activity Intensity and Aerobic Fitness on the Anthropometric Index and Serum Uric Acid Concentration in People with Obesity. Internal Medicine. 50: 2121-2128.
Lamina, S., Okoye, G. C. (2012). Effects of Aerobic Exercise Training on Psychosocial Status and Serum Uric Acid in Men with Essential Hypertension: A Randomized Controlled Trial. Annals of Medical and Health Sciences Research. 2 (2): 161-168.
Li-ling HUANG, Chien-Tsai HUANG, Mei-lien CHEN, I-Fang Mao. (2010). Effects of Profuse Sweating Induced by Exercise on Urinary Uric Acid Excretion in a Hot Environment. Chinese Journal of Physiology. 53 (4): 254-261.