Application of Clostridium Botulinum Toxin Type D to Control Plateau Zokors in Qinghai–Tibet Plateau Pastoral Areas
Animal and Veterinary Sciences
Volume 7, Issue 2, March 2019, Pages: 40-45
Received: Dec. 31, 2018;
Accepted: Feb. 1, 2019;
Published: May 17, 2019
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Shengqing Li, Qinghai Academy of Animal Science and Veterinary Medicine, Xining, China; Department of Animal Medicine, Northwest Agriculture and Forestry University, Yangling, China
Xiyun Zhang, Qinghai Academy of Animal Science and Veterinary Medicine, Xining, China
Huaixi Liu, Qinghai Academy of Animal Science and Veterinary Medicine, Xining, China
Tongzuo Zhang, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, China
Guoyuan Hu, Qinghai Academy of Animal Science and Veterinary Medicine, Xining, China
Zhining Li, Qinghai Academy of Animal Science and Veterinary Medicine, Xining, China
Tingting Wang, Qinghai Academy of Animal Science and Veterinary Medicine, Xining, China
Rong Huang, Qinghai Academy of Animal Science and Veterinary Medicine, Xining, China
Yanming Zhang, Department of Animal Medicine, Northwest Agriculture and Forestry University, Yangling, China
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The feasibility of Clostridium botulinum toxin type D as a novel biological rodenticide to control plateau zokors was explored. In this study, Horn’s method was used to determine the gavage LD50 of C. botulinum toxin type D to plateau zokors. Modified Karber metho was employed to determine the oral LD50 of granular and wheat baits. Results showed that the gavage LD50 was 5840 MLD/kg (the reliable line is 3430–9950 MLD/kg) and the oral LD50 values of granular and wheat baits were 0.8339 and 1.319 g/kg, respectively, which indicated that plateau zokors are sensitive to this toxin. The palatability of wheat and homemade granular baits to plateau zokors was measured. Selective feeding coefficients were 1.33 and 1.10, whereas nonselective feeding coefficients were 0.81 and 0.60, respectively. A plot experiment of different toxin concentrations to kill zokors showed that homemade granular bait (10000 MLD/g) had the best effect. The average efficiency rate was 89.83%. This study showed the feasibility of controlling plateau zokors by using botulinum toxin type D.
Clostridium Botulinum Toxin Type D, Rodent Control, Plateau Zokor, LD50
To cite this article
Application of Clostridium Botulinum Toxin Type D to Control Plateau Zokors in Qinghai–Tibet Plateau Pastoral Areas, Animal and Veterinary Sciences.
Vol. 7, No. 2,
2019, pp. 40-45.
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
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