Economic Importance and Control Techniques of Lumpy Skin Diseases
Animal and Veterinary Sciences
Volume 3, Issue 2, March 2015, Pages: 58-66
Received: Feb. 22, 2015; Accepted: Mar. 9, 2015; Published: Mar. 15, 2015
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Birhanu Hailu, Samara University, College of Veterinary Medicine, Department of Veterinary Epidemiology and Preventive Medicine, Samara, Ethiopia
Gezahign Alemayehu, Samara University, College of Veterinary Medicine, Department of Veterinary Epidemiology and Preventive Medicine, Samara, Ethiopia
Nuru Seid, Samara University, College of Veterinary Medicine, Department of Veterinary Epidemiology and Preventive Medicine, Samara, Ethiopia
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Lumpy skin disease (LSD) is an acute infectious disease of cattle endemic in most Sub-Saharan African countries. It is economically devastating viral diseases which cause several financial problems in livestock industries as a result of significant milk yield loss, infertility, abortion and death. It is caused by lumpy skin diseases virus of capripoxvirus. The disease is characterized by fever, enlarged lymph nodes, firm, and circumscribed nodules in the skin and ulcerative lesions particularly in the mucous membrane of the mouth. It occurs in all agro climatic conditions and has the potential to extend its boundaries. It is transmitted by insect vectors among the cattle sharing similar grazing and watering areas and those congregate in the same barn. Good understanding of epidemiology, economic significance and control mechanisms of the disease enabled to design suitable control measures. LSD could be diagnosed using appropriate serological and molecular techniques. Effective control measure of the disease is achieved through mass vaccination though separation and culling of infected animals are optional methods.
Lumpy Skin Disease, OIE, Epidemiology, Control, Transmission
To cite this article
Birhanu Hailu, Gezahign Alemayehu, Nuru Seid, Economic Importance and Control Techniques of Lumpy Skin Diseases, Animal and Veterinary Sciences. Vol. 3, No. 2, 2015, pp. 58-66. doi: 10.11648/j.avs.20150302.15
Alexander, R. A., Plowright, W., and Haig, D. A., (1957). Cytopathogenic agents associated with lumpy-skin disease of cattle. Bull. Epiz. Dis. Afr., 5:489-492.
Ali, A. A., Esmat, M., Attia, H. Selim, A. and Abdel-hamid, Y. M., (1990). Clinical and Pathological Studies of on the lumpy skin disease in Egypt. The veterinary record, 127:549-550.
AUSVETPLAN., (2009). Australian Veterinary Emergency Plan, Disease Strategy, Lumpy skin disease.
Babiuk, S., Bowden. T. R., Boyle. D. B., Wallace D. B. and Kitching R. P., (2008). Capripoxviruses: An Emerging Worldwide Threat to Sheep, Goats and Cattle. TransboundaryEmergeging Disease. 55(7):263-72.
Bagla, P. V., (2005). The demonstration of the lumpy skin disease virus in semen of the experimentally infected bulls using different diagnostic techniques, MSc thesis.
Barnard, B. H. J., Munz, E., Dumbell, K. and Prozyesky, L., (1994). Lumpy skin disease. In: Infectous disease of livestock with special reference to South Africa. 1:604-612.
Brenner, J., Haimovitz, M., Orone E., Stram Y., Fridgut O., Bumbarov V., Kuznetzova, L., Oved Z., Waerrman A., Garazzi S., Perl S., Lahav D., Edery N. &Yadin H., (2006). Lumpy skin disease (LSD) in a large dairy herd in Israel. Isr. J. Vet. Med., 61:73–77.
Bruce F., Eldridge, Edman J. D., (2004). Medical Entomology: A Textbook on Public Health and Veterinary Problems Caused by Arthropods. Capripox viruses Lumpy skin disease. 488p.
Buller, R. M., Arif B. M., Black D. N., Dumbell K. R., Esposito J. J., (2005). Virus Taxonomy: Classification and Nomenclature of Viruses. Eighth Report of the International Committee on Taxonomy of Viruses, pp. 117–133. Elsevier Academic Press, San Diego.
Carn, V. M., (1993). Control of capripoxvirus infections. Vaccine, 11:1275–1279.
Carn, V. M. and Kitching, R. P., (1995). An investigation of the possible route of the transmission of lumpy skin disease virus. Epidemiology and infection. 114:219-226.
Carn, V. M., (2002). Control of Capripoxvirusinfections11(13):1275–1279.
Carter, G. R., Wise, D. J. and Flores, E. F., (2005). A Concise Review of Veterinary Virology, G. R. Carter, D. J. Wise and E. Furtado Flores (Eds. ) International Veterinary Information Service, Ithaca, New York, USA.
CFSPH ., (2008) . The Center for Food Security and Public Health, Iowa State University, College of Veterinary Medicine and Institution of International cooperation in Animal Biologics, an OIE collaborating center.
Chihota, C. M., Rennie, L. F., Kitching, R. P. and Mello, R P. S., (2003). Attempted mechanical transmission of lumpy skin disease virus by biting insects, Medical and Veterinary Entomology 17:294–300.
Committee on Managing Global Genetic Resources, 1993
Coetzer, J. A. W. and Venter., E. H., (2010). A Potential Role for Ixodid (Hard) Tick Vectors in the Transmission of Lumpy Skin Disease Virus in Cattle. Transboundry and Emerging Disease. 58:93-104.
Davies, F. G., Kraussh., Lund, L. J. and Taylor M., (1971). The laboratory diagnosis of lumpy skin disease. Res. Vet. Sci., 12:123–127.
Davies, F. G., (1981). Lumpy skin disease. In: Virus Diseases of Food Animals, Gibbs EPJ (ed), Academic Press, London, 2 :751–764.
Davies, F. G., (1991a). Lumpy skin disease of cattle: A growing problem in Africa and Near East. world Animal Review; 68:37-42.
Davies, F. G., (1991b). Lumpy skin disease, an African capripoxvirus disease of cattle. Br. Vet. J. 147:489–503.
Diesel, A. M., (1949). The Epizootiology of Lumpy Skin Disease in South Africa. In Proceedings of the 14th International Veterinary Congress, London, U. K., pp. 492-500.
Dohoo, I., Martin, W., Stryhn, H., (2003). Measures of Associations, Veterinary Epidemiological Research, 2ndedition, Canada. pp121-137 and pp65-82.
Getachew, G., Bonnet, P., Roger, F. and Waret-Szkuta, A., (2011). Epidemiological aspects and Financial Impacts of the Lumpy Skin Disease in Ethiopia, PhD thesis. pp87-110.
Getachew, G., Waret-Szkuta, A., Grosbois, V., andJacquite, P., (2010). Risk Factors Associated with observed clinical lumpy skin disease in Ethiopia. PhD thesis. PP68-84.
Getachew, G., Grosbois, V., Waret-Szkuta, A., Babiuk S, Jacquiet P, Roger F., (2012). Lumpy skin disease in Ethiopia: Seroprevalence study across different agro-climate zones. p1
Green, H., (1959). Lumpy skin disease; its effect on skin and hide and a comparison in this respect with some other skin diseases. Bulletin of the epizootic disease of Africa, 7:63-79.
Greth., A, Gourreau, J. M., Vassart, M., Nguyen-Ba-Vy, Wyers, M., Lefevre. P. C., 1992. Capripoxvirus disease in an Arabian oryx (Oryx leucoryx) from Saudi Arabia. J Wildl Dis. 28(2):295-300.
Haig, D. H., (1957). Lumpy skin disease. Bulletin of Epizootic disease of Africa 5:421-430.
House, J. A., 1990. Lumpy Skin Disease. In Proceedings of the 93rd Annual Meeting of the United States Animal Health Association, Las Vegas, Nevada, . Pp. 305-314.
House, J. A., Wilson, T. M., Elnakashly, S., Karim, I. A., Ismail, I., ELDanaf, N., Moussa, A. M., and Ayoub, N. N., (1990). The isolation of lumpy skin Disease virus and bovine herpesvirus-4 from cattle in Egypt. J. Vet. Diagn. Invest. 2: 111-115.
ICTV (2002), International Committee on Taxonomy of Viruses, Taxonomy of Pox virus
Ireland, D. C., and Binepal, Y. S., (1998). Improved detection of capripoxvirus in biopsy samples by PCR, Journal of Virological methods, 74:1-7.
Irons, P. C., Tuppurainen, E. S. M., and Venter, E. H., (2005). Excretion of the lumpy skin disease virus in bull semen. MSc dissertation.
Kholy, A. A. E., Soliman, H. M. T. and Abdelrahman, K. A., (2008). Polymerase chain reaction for rapid diagnosis of a recent lumpy skin disease virus incursion to Egypt, Veterinary Serum & Vaccine Research Institute. Arab J. Biotech., 11 (2): 293-302.
Kitching, R. P. and Mellor, P. S., (1986a). Insect transmission of capripoxvirus. Research in Veterinary Science 40:255–258.
Kitching, R. P. &Smale, C., (1986b). Comparison of the external dimensions of capripoxvirus isolates. Res. Vet. Sci. 41:425–427.
Kitching, R. P., Bhat, P. P., and Black, D. N., (1989). Characterization of the African Strain of Capri pox virus, AFRC Institute for animal Health Pirbright laboratory, Epidemic. Inf. 102:335-343.
Kitching, P., and Carn, V., (2000). The involvement of wild life and insect vectors in the epidemiology of Lumpy skin disease in South Africa.
Kumar, S. M., (2009). An outbreak of Lumpy Skin Disease in a Holstein Dairy Herd in Oman: A Clinical report, Asian Journal of Animal and Veterinary Advances 6(8):851-859.
Lumpy skin disease contingency plan for the Netherlands(2002). Veterinary Services, Ministry of Agriculture and Fisheries. pp1-22.
Mac Owen, K. D. S., (1959). n the epizootiology of lumpy skin disease during the first year of its occurrence in Kenya. Bull. Epiz. Dis. Afr., 7:7-20.
Magoricohen, R., Louzoun, Y., Herziger, Y., Oron, E., Arazi, A., Tuppurainen, E., Shipgel, Y. N., Klement, E., (2012). Mathematical modeling and evaluation of the different routes of transmission of lumpy skin disease virus, Veterinary Research 43:1.
Mathews, R. E. F., (1982). Classification and nomenclature of viruses. Intervirol. 17:1-99.
McFadden, G., (2005). Poxvirus tropism. Nat. Rev. Microbiol. 3:201–213.
Merk Veterinary Manual, (2011)., Integumentary System : Pox Diseases : Lumpy Skin Disease, Economic impact of lumpy skin disease.
Mlangwa, J. E. D., and Samui, K. L., (1996). The nature of Animal health Economics and Veterinary Epidemiology, Rev. sci. tech. Off. int. Epiz., 15 (3) :797-812.
Murphy, F. A., Gibbs, E. P. J., Horzinek, M. C., Studdert, M. J., (1999). Veterinary Virology. Poxviridae, pp277-292
OIE . 2010. OIE Manual of Diagnostic Tests and Vaccines for Terrestrial Animals . Lumpy skin disease. Chapter2. 4. 14. pp768-778.
Osuagwuh, U. I., (2006). Semen Quality and the Excretion of Lumpy skin disease Virus in Semen Following Vaccination and Experimental Challenge of Vaccinated Bulls, MSc thesis, Pretoria University, pp3-28.
Otte, M. J. and Chilondda, P., (1996). An Introduction to animal health economics, Livestock information, Sector analysis and policy branch, Animal production and health division.
Preeze, J. D., (2006). Control of Lumpy Skin Disease, Vaccinate Every year for Lumpy skin disease.
Pyride, . J and Coakley, M., (1959). Lumpy skin disease: Tissue culurestudies, Bulletin of Epizootic disease of Africa 7:37-50.
Radostitis, MO., Gay, C., Hinchcliff., and Constable, PD., (2006). Veterinary Medicine, Text book of the disease of Cattle, Sheep, Goat, pig and horses, 10th edition.
Regassa, C., (2003). Preliminary study of the Major skin diseases of cattle coming to Nekemit Veterinary Clinic, Faculity of veterinary Medicine, Addis AbebaUnivesity, Debrezite. DVM Thesis
Salib, F. A., and Osman, A . H., (2011). Incidence of lumpy skin disease among Egyptian cattle in Giza Governorate, Egypt, Veterinary World, Vol. 4 (4):162-167.
Shen, J. Y., Shephard, E., Douglass1, N, Johnston, N., Adams, C., Williamson, C., and Anna-LiseWilliamson, A. L., (2011). A novel candidate HIV vaccine vector based on the replication deficient Capri poxvirus, Lumpy skin disease virus.
Thomas, L., (2002). Lumpy-skin disease, a disease of socio-economic importance.
Traktman, P., (1996). Pox virus DNA replication, DNA replication in Eukaryotic cells, Department of cell biology and microbiology, Cornell University Medical College, New York.
Tuppurainen, E. S. M and Oura. C. A. L., (2011). Review: Lumpy Skin Disease: An Emerging Threat to Europe, the Middle East and Asia, Institute for Animal Health, Pirbright, Surrey, UK.
Tuppurainen, S. M., (2005). Detection of the lumpy skin disease virus in samples of the experimentally infected cattle using different diagnostic techniques, MSc thesis.
Valones, A. A., Guimarães, L. R., Brandão. LA. C., de, Souza. P. R. E., Carvalho. A. D. T., Crovela, S., 2009. Principles and Applications of polymerase chain reaction in medical diagnostic fields: a review Brazilian Journal of Microbiology 40:1-11.
Vorster, J. H., Mapham, P. H., (2008). Lumpy skin disease, Livestock health and Production review.
Weiss, W. E., (1968). Lumpy Skin disease. In Emerging Diseases of Animals.
Woods, J. A., (1988), Lumpy Skin Disease, Review. Tropical AnimalHealthproduction. 20:11-17
Wood, J. A., (1990). Lumpy skin disease. In: Virus Infections of Ruminants, Dinter Z and Morein B (eds), Elsevier, Amsterdam, pp 53–67.
Yeruham, I., Nir, O., Braverman, Y., Davidson, M., Grinstein, H., Haymovitch, M. andZamir, O., 1995. Spread of Lumpy skin disease in Israel dairy herds. The Veterinary record 137: 91-93.
Young, E., BassonP. A., and K. E. Weiss., 1970: Experimental infection of game animals with lumpy skin disease virus prototype strain Neethling. OnderstepoortJ. Vet. Res. 37: 79–87.
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