Papular Cutaneous Amyloidosis Associated with Multiple Myeloma
Science Journal of Clinical Medicine
Volume 5, Issue 2, March 2016, Pages: 16-19
Received: Jan. 23, 2016; Accepted: Feb. 24, 2016; Published: Mar. 4, 2016
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Authors
Al-Raddadi Reem, Department of Dermatology, Saint Louis Hospital, University Paris 13, Paris, France
Abbaspour Valiollah, Department of Dermatology, Aristide Le Dantec Hospital, University Cheikh Anta DIOP of Dakar, Senegal BP 3001, Dakar, Senegal
Ndiaye Maodo, Department of Dermatology, Aristide Le Dantec Hospital, University Cheikh Anta DIOP of Dakar, Senegal BP 3001, Dakar, Senegal
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Abstract
We report a case of papular cutaneous amyloidosis associated with multiple myeloma in a 52 years old man who presented papular xanthoma like lesions in periorbital areas and scrotum with severe bone pain in thoracic and lumbar spinal column and lower limbs. Cutaneous histopathology revealed the presence of amorphous deposits in papillary dermis surrounded with small lymphoid infiltrates with erythrocyte containing slots. Congo red staining was positive and bone marrow aspiration showed dysplastic plasma cells. Lytic lesions were observed in long bones and skull radiography. 24 hours Proteinuria was 3.69 g / l. A combination of Melphalan and prednisone as treatment could restore renal function without any change in skin lesions after 14 months.
Keywords
Amyloidosis, Papular, Multiple Myeloma
To cite this article
Al-Raddadi Reem, Abbaspour Valiollah, Ndiaye Maodo, Papular Cutaneous Amyloidosis Associated with Multiple Myeloma, Science Journal of Clinical Medicine. Vol. 5, No. 2, 2016, pp. 16-19. doi: 10.11648/j.sjcm.20160502.11
Copyright
Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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