The Current Status of Cutaneous Leishmaniasis and the Pattern of Lesions in Ochollo Primary School Students, Ochollo, Southwestern Ethiopia
Science Journal of Clinical Medicine
Volume 3, Issue 6, November 2014, Pages: 111-116
Received: Oct. 3, 2014;
Accepted: Oct. 11, 2014;
Published: Oct. 30, 2014
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Gessessew Bugssa, Institute of Biomedical Sciences, College of Health Sciences, Mekelle University, Mekelle, Ethiopia
Asrat Hailu, Department of Micrbiology, Immunology and Parasitoloogy, Medical faculty, Addis Ababa University, Addis Ababa, Ethiopia
Balem Demtsu, Department of Midwifery, College of Health Sciences, Mekelle University, Mekelle, Ethiopia
Background: Leishmaniasis is a vector borne disease caused by the obligate intracellular protozoan leishmania. Objective:To assess the prevalence of cutaneous leishmaniasis and pattern of lesions in Dega Ochollo primary school students, Ochollo, Southwestern Ethiopia. Methods: A cross-sectional study was carried out among 523 school children aging between 6 to 25 years. The students were physically examined for the presence of scar and active lesions. Skin slit and blood were collected from students with suspected active lesions of cutaneous leishmaniasis. Scraps were cultured in Nicolle-Novy-MacNeal(NNN) medium and serological tests were performed using direct agglutination test (DAT). Results: The overall prevalence of tegumentary leishmaniasis including both scar and active lesions among the 523 students which underwent physical examination was 65.8 %. Besides, the study revealed that 64.8% of the participants had current and/or past lesion of cutaneous leishmaniasis. The prevalence of Mucocutaneous leishmaniasis and recidivan was 0.2% and 0.8%, respectively. Three hundred and thirteen (59.8%) students were with scar and 21(4.01%) were with active lesions whereas 8(1.5%) of the cases had both scar and active lesions. Majority (49.71%) of the participants belonging to the age group 11-15 years old were the most affected group (p-value<0.05). The average number of scars and lesions per patient was calculated to be 1.5 and 1.7, respectively. Majority (64.17%) of the cases had single scars while 22.74%, 7.48%, and 5.61% of them had double, triple, and four and above, respectively. The scars were more localized above the neck (82.16%) where the highest (54.56%) proportion of the scars was distributed on check. Of the 29 participants who had active lesions, 4(13.8%) of them were found to be culture positive and one patient was also positive for DAT out of these culture positive patients. One smear positive sample was also found among the samples which were positive for NNN medium. Conclusions: cutaneous leishmaniasis is prevalent in the area causing disfigurement and resulting social stigmatization. This calls for the implementation of prevention and control measures including treatment of infected individuals.
The Current Status of Cutaneous Leishmaniasis and the Pattern of Lesions in Ochollo Primary School Students, Ochollo, Southwestern Ethiopia, Science Journal of Clinical Medicine.
Vol. 3, No. 6,
2014, pp. 111-116.
Roberts MT. Current understandings on the immunology of leishmaniasis and recent developments in prevention and treatment. British Medical Bulletin. 2006; 75 and 76: 115-30.
Demirel R, Erdogan S. Determination of high risk regions of cutaneous leishmaniasis in Turkey using spatial analysis. Türkiye Parazitoloji Dergisi. 2009; 33: 8-14.
Desjeux P. Leishmaniasis: Public health aspects and control. Clinics in Dermatology. 1996; 1: 417-423.
World Health Organization. Urbanization: an increasing risk factor for leishmaniasis. Weekly Epidemiological Record. 2002; 44:365-372.
Markle WH, Makhoul K. Cutaneous Leishmaniasis: Recognition and treatment. American Family Physician. 2004; 69:1455-1460.
World Health Organization. Control of leishmaniasis, report by the secretariat, 118th session, provisional agenda, 2006.
World Health Organization. Communicable Disease Control in Emergencies - A Field Manual; 2003 pp 223.
Khan SJ, Muneeb S. Cutaneous leishmaniasis in Pakistan. Dermatology. 2005; 11: 4.
World Health Organization. Control of leishmaniasis. Report by the Secretariat, 2007.
Hailu A, Gebre-Michael T, Berhe G, Balkew M. Leishmaniasis: In Yemane- Berhane T, Hailemariam D, Kloos H (eds). The Epidemiology and Ecology of Health and Disease in Ethiopia; 615-634 pp.3rd edition, Shama Books, Addis Ababa, 2006.
González U, Pinart M, Reveiz L, Alvar J. Interventions for Old World cutaneous leishmaniasis. Cochrane Database of Systematic Reviews. 2009; 4:1-114.
Alrajhi A. Cutaneous leishmaniasis of the Old World. Skin Therapy Letter. 2003; 8: 1.
Chappuis F, Sundar S, Hailu A, Ghalib H, Rijal S, Peeling RW, et al. Visceral leishmaniasis: what are the needs for diagnosis, treatment and control? Nature Reviews| Microbiology. 2007; 5:873-882.
Hailu A, Muccio TD, Abebea T, Hunegnaw M, Piet A, Kagerd PA, et al. Isolation of Leishmania tropica from an Ethiopian cutaneous leishmaniasis. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2006; 100:53-58.
Ashford RW, Bray MA, Hutchinson MP, Bray RS. The epidemiology of cutaneous leishmaniasis in Ethiopia. Transactions of the Royal Society of Tropical Medicine and Hygiene. 1973; 67: 568-601.
Negera E, Gadisa E, Yamuah L, Engers H, Hussein J, Kuru T, et al. Outbreak of cutaneous leishmaniasis in Silti woreda, Ethiopia. Risk factor assessment and causative agent identification.Transactions of the Royal Society of Tropical Medicine and Hygiene. 2008; 102:883-890.
Menngistu G, Laskay T, Gemetchu T, Humber D, Ersamo M, Evans D, et al. Cutaneous leishmaniasis in south-western Ethiopia:Ochollo revisited. Transactions of the Royal Society of Tropical Medicine and Hygiene. 1992; 86:149-153.
Lindtjorn B. Cutaneous leishmaniasis in the Sidamo highlands. Ethiopian Medical journal. 1983; 9:97.
Wilkins HA. Studies on leishmaniasis in Ethiopia.Vi;incidence rates of Cutaneous leishmaniasis at Meta Aabo. Annals of Tropical Medicine and Parasitology. 1972; 66:457-465.
Lemma W, Erenso G, Gadisa E, Balkew M, Gebre-Michael T, Hailu A. A zoonotic focus of cutaneous leishmaniasis in Addis Ababa, Ethiopia. Parasites & Vectors.2009; 2:60.
Nezhad HA, Borhani M, Norouzi M, Merzaie M. Cutaneous Leishmaniasis in school children in a border area at southwest of Iran. Sci Parasitol. 2012; 13(4):153-158.
Al-Jawabreh A, Barghuthy F, Schnur LF, Jacobson RL, Schonian G, Abdeen Z. Epidemiology of cutaneous leishmaniasis in endemic area of Jericho, Palestine. East Mediterran Journal of Health. 2003; 9: 805-815.
Sharifi I, Poursmaelian S, Aflatoonian MZ, Ardakani RF, Mirzaei M, Fekri AR et al. Emergence of a new focus of anthroponotic cutaneous leishmaniasis due to Leishmania tropical in rural communities of Bam district after the earthquake, Iran. Tropical Medicine and International Health. 2011; 16(4): 510–513.
Fazaeli A, Fouladic B, Sharifi I. Emergence of cutaneous leishmaniasis in a border area at south-east of Iran: an epidemiological survey. J. Vector Borne Dis. 2009; 46:36-42.
Desjeux P. The increase in risk factors for the leishmaniasis worldwide. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2001; 95, 239-243.
Yaghoobi-Ershadi MR, Hanafi-Bojd AA, Akhavan AA, Zahrai-Ramazani AR, Mohebali M. Epidemiological study in a new focus of cutaneous leishmaniasis due to Leishmania major in Ardestan town, central Iran. Acta Trop. 2001; 79:115-121.
Hailu A. The use of direct agglutination test (DAT) in the serological diagnosis of Ethiopian cutaneous leishmaniasis.Diagnostic. Microbiology and Infectious Disease; 2002; 42: 251-256.