Antibiotic Utilization in a Dental Teaching Hospital in Yogyakarta, Indonesia
Science Journal of Clinical Medicine
Volume 3, Issue 3, May 2014, Pages: 37-42
Received: May 16, 2014; Accepted: May 29, 2014; Published: May 30, 2014
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Mayu Winnie Rachmawati, Department of Drug Management and Policy, Graduate School of Natural Science and Technology, Kanazawa University, Japan
Naoko YOSHIDA, Department of Drug Management and Policy, Graduate School of Natural Science and Technology, Kanazawa University, Japan
Hirohito TSUBOI, Department of Drug Management and Policy, Graduate School of Natural Science and Technology, Kanazawa University, Japan
Kazuko KIMURA, Department of Drug Management and Policy, Graduate School of Natural Science and Technology, Kanazawa University, Japan
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Background: Various antibiotics are prescribed by dental practitioners to treat odontogenic infections. However, there has been no comprehensive study of antibiotics use in a dental teaching hospital in a developing country using World Health Organization (WHO) dose measurement units. Objective: This study was designed to evaluate the use of antibiotics among dental outpatients at a dental teaching hospital in Yogyakarta, Indonesia. Methods: A cross-sectional study of outpatients’ medical records was carried out in order to identify oral antibiotics administered during January-December 2011. Prescriptions that included antibiotics (N=2024) were separated from total prescriptions collected from medical records. The source and type of antibiotics prescribed and the diagnoses were recorded. Anatomical Therapeutic Chemical classification and Defined Daily Dosage (DDD) measurement units were assigned, and the information was compiled, coded, analyzed in accordance with WHO guidelines. Results: Thirteen different antibiotics were prescribed and all were administered to patients. Antibiotics were frequently prescribed contrary to generally accepted criteria and there was wide variation in prescribing. The most commonly prescribed antibiotic was amoxicillin (78.8%), followed by clindamycin (9.0%) and metronidazole (5.0%). The dental diagnosis most frequently reported was pulp gangrene (26.7%), followed by pulp necrosis (8.8%) and impaction-related problems (6.4%). There was a marked increase in total antibiotics use expressed in defined daily dose (DDD) per 1000 patient visit per month during September to November, which might have been associated with seasonal change or availability of student health insurance at the start of the academic year. Conclusion: Our findings show a high level of inappropriate antibiotics usage at a dental teaching hospital in Indonesia, and indicate that there is a need for educational initiatives and guidelines to promote best practice and appropriate use of antibiotics in this hospital.
Antibiotics Utilization, Dental Teaching Hospital, Yogyakarta, Indonesia
To cite this article
Mayu Winnie Rachmawati, Naoko YOSHIDA, Hirohito TSUBOI, Kazuko KIMURA, Antibiotic Utilization in a Dental Teaching Hospital in Yogyakarta, Indonesia, Science Journal of Clinical Medicine. Vol. 3, No. 3, 2014, pp. 37-42. doi: 10.11648/j.sjcm.20140303.12
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