Recurrent Cholestatic Jaundice in Lean Nonalcoholic Steato-Hepatitis in a 27 Year Male
International Journal of Nutrition and Food Sciences
Volume 4, Issue 4, July 2015, Pages: 483-485
Received: May 27, 2015;
Accepted: Jun. 11, 2015;
Published: Jul. 4, 2015
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Ajay Vardaan, Department of Medical Gastroenterology, King George’s Medical University, Lucknow, India
Amar Deep, Department of Medical Gastroenterology, King George’s Medical University, Lucknow, India
Recurrent cholestasis is not described as a feature of nonalcoholic steato-hepatitis (NASH). We describe a lean patient with recurrent jaundice and pruritus whose liver biopsy showed feature of NASH. His laboratory work up failed to establish any other etiology. His symptoms proved on balanced nutrition.
Recurrent Cholestatic Jaundice in Lean Nonalcoholic Steato-Hepatitis in a 27 Year Male, International Journal of Nutrition and Food Sciences.
Vol. 4, No. 4,
2015, pp. 483-485.
Kausik D, Abhijit C. Lean NASH: distinctiveness and clinical implication. Hepatol Int, 2013, 7 (Suppl 2) S806 S813.
Charls S. Libeber. Relationship between nutrition, alcohol use and liver disease. Alcohol Research and Health. 2003: Vol.27, No.3.
Tung BY, Carithers RL. Cholastasis and alcoholic liver disease. 1999: Clin Liver Dis. 3:585-601.
Afshani P, Littenberg GD, Wollman J, Kaplowitz N. Significance of microscopic cholangitis in alcoholic liver disease. Gastroenterology. 1978; 75:1045-1050.
Lee RG, Alcoholic and Nonalcoholic Steatohepatitis Pathology. In Clinical Pathological Correlation in Liver Disease: Approaching the Next Millennium. Bloom JR, Goodman ZD, IShak KG, (eds). Washington DC, Armed Forces Institute of Pathology, American Registry of Pathology, AASLD, 1998; pp 274-283.
Brunt EM, Janney GG, DiBisceglie AM, Neuschwander-Tetri BA, Bacon BR. Nonalcoholic Steatohepatitis: A Proposal for Garding and Staging the Histological Lesions. Am J Gastroenterol, 1999; 94:2467-2474 crossRef.
European Association for the Study of the Liver / Journal of Hepatology 51 (2009) 237–267.
Armstrong MJ, Houlihan DD, Bentham L, et al. Presence and severity of non-alcoholic fatty liver disease in a large prospective primary care cohort. J Hepatol 2012; 56:234–40.
Bellentani S, Tiribelli C, Saccoccio G, et al. Prevalence of chronic liver disease in the general population of northern Italy: the Dionysos Study. Hepatology 1994; 20:1442–9.
Browning JD, Szczepaniak LS, Dobbins R, et al. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology 2004;40:1387–95.
Bellentani S, Bedogni G, Miglioli L, et al. The epidemiology of fatty liver. Eur J Gastroenterol Hepatol 2004; 16:1087–93.
Bugianesi E, Leone N, Vanni E, et al. Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma. Gastroenterology 2002; 123:134–40.
Charlton MR, Burns JM, Pedersen RA, et al. Frequency and outcomes of liver transplantation for nonalcoholic steatohepatitis in the United States. Gastroenterology 2011; 141:1249–53.
Yang SQ, Zhu H, Li Y, Gabrielson K, Trush MA & Diehl AM: Mitochondrial Adaptations to Obesity-Related Oxidant Stress. Arch Biochem Biophys. 2000; 378(2):259-268.
Torricelli P., Ferorelli P., De Martino A., Antonelli F., Beninati S.. The Influence of Preventive Multiple Micronutrients Supplementation on Liver Steatosis in High-cholesterol Fed C57BL6/N Mice. American Journal of Life Sciences. Vol. 1, No. 2, 2013, pp. 55-60 doi: 10.11648/j.ajls.20130102.16