The Correlation of Symptoms Severity and Objective Measures in Patients with Lower Urinary Tract Symptoms
Clinical Medicine Research
Volume 2, Issue 6, November 2013, Pages: 135-139
Received: Sep. 11, 2013;
Published: Oct. 20, 2013
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Basri Cakiroglu, Hisar Intercontinental Hospital, Department of Urology, 34768 Umraniye, Istanbul, Turkey
Ramazan Gozukucuk, Hisar Intercontinental Hospital, Department of Infectious and Clinical Microbiology, 34768 Umraniye, Istanbul, Turkey
Orhun Sinanoglu, Maltepe University, Medical School Department of Urology, 34857 Maltepe, Istanbu,Turkey
Suleyman Hilmi Aksoy, Hisar Intercontinental Hospital, Department of Radiology, 34768 Umraniye, Istanbul,Turkey
Tuncay Tas, Taksim Training and Research Hospital, Department of Urology, 34433 Taksim, Istanbul, Turkey
Seyit Erkan Eyyupoglu, Sabuncuoglu Serefettin Training and Research Hospital, Department of Urology, 05200 Amasya, Turkey
Bekir Sami Uyanik, Hisar Intercontinental Hospital, Department of Clinical Biochemistry, 34768 Umraniye, Istanbul, Turkey
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Purpose: To evaluate the correlation between international prostate symptom score (IPSS) and objective measures of lower urinary tract symptoms to estimate the grade of infravesical obstruction in benign prostatic hyperplasia (BPH). Methods: The data of 152 male patients examined in urology outpatient clinic with lower urinary tract symptoms (LUTS) were retrospectively rewieved between January 2010 and December 2011. Prostate volume, detrusor wall thickness (DWT) and post voiding residue (PVR) were evaluated with suprapubic ultrasound. The patients were distributed in three groups according to IPSS values; 1st, lower IPSS group (n=39), 2nd, moderate IPSS group (n=80) and 3rd, .higher IPSS group (n=33). IPSS, BWT, prostate volume, postvoiding residue (PVR), and maximum urine flow (Qmax) values were compared. Results: The mean age was 52.9 ±9.0 years. There were significant differences between the three groups for total PSA, in terms of prostate volume, DWT, PVR, Qmax, Qave values. There was a significant correlation between IPSS questionnaire results and PVR, Qmax and Qave (P< 0.05). PVR, Qmax and PVR values revealed especially strong positive correlations with symptoms severity or IPSS (Pearson /Spearman’s correlation coefficients were 0.441; p < 0.000 and 0.446; p < 0.000 respectively; Table 3). Conclusions: There are significant correlations between symptoms severity (IPSS) and objective BPH-related parameters, such as age, PSA, prostate volume, DWT, PVR, Qmax, Qave and QoL. The measurements of especially DWT, PVR and Qmax are promising noninvasive tools to predict the grade of LUTS in men and is reflected in IPSS severity.
Uroflowmetry, Prostate Volume, PSA, IPSS, DWT, BPH, LUTS
To cite this article
Suleyman Hilmi Aksoy,
Seyit Erkan Eyyupoglu,
Bekir Sami Uyanik,
The Correlation of Symptoms Severity and Objective Measures in Patients with Lower Urinary Tract Symptoms, Clinical Medicine Research.
Vol. 2, No. 6,
2013, pp. 135-139.
Roehrborn CG, McConnell JD. Etiology,pathophysiology, epidemiology, and natural history of benign prostatic hyperplasia. In: Campbell’s urology. 8th ed. Philadelphia: Saunders, 2002. p. 1309–1311
AUA Practice Guidelines Committee. AUA guideline on management of benign prostatic hyperplasia (2003). Chapter 1: diagnosis and treatment recommendations. J Urol, 2003. 170: p. 530-547.
Belal M, Abrams P. Noninvasive methods of diagnosing bladder outlet obstruction in men. Part 1. Non-urodynamic approach. J Urol, 2006. 176: p. 22–28.
Wang JY, et al., Relationship between lower urinary tract symptoms and objective measures of benign prostatic hyperplasia: a Chinese survey. Chin Med J (Engl), 2008. 20; 121(20): p. 2042-5.
Wu SL, et al., Natural history of benign prostatic hyperplasia. Chin Med J, 2006. 119: p. 2085-2089.
Barry MJ, et al., The American Urological Association symptom index for benign prostatic hyperplasia. The Measurement Committee of the American Urological Association. J Urol, 1992. 148: p. 1549-1557.
Madersbacher S, et al., Is obstruction predictable by clinical evaluation in patients with lower urinary tract symptoms? Br J Urol, 1997. 80: p. 72-77.
Kezzeldin LA, et al., Correlation between uroflowmetry, prostate volume, postvoid residue, and lower urinary tract symptoms as measured by the international prostate symptom score. Urology, 1996. 48: p. 393-397.
Tubaroa A, Vecchia CA. The relation of lower urinary tract symptoms with life-style factors and objective measures of benign prostatic enlargement and obstruction: an Italian survey. Eur Urol, 2004. 45: p. 767-772.
Wang JY, et al., Relationship between lower urinary tract symptoms and objective measures of benign prostatic hyperplasia: a Chinese survey Chin Med J, 2008. 121(20): p. 2042-2045
Tokgoz O, et al., Diagn Interv Radiol, 2012. 18: p. 277–281.
Li MK, et al., An Asian multinational prospective observational registry of patients with benign prostatic hyperplasia, with a focus on comorbidities, lower urinary tract symptoms and sexual function. BJU Int, 2008. 101: p. 197-202.
Zhang P, Wu ZJ, Gao JZ. Influence of bladder outlet obstruction and detrusor contractility on residue urine in patients with benign prostatic hyperplasia. Chin Med J, 2003. 116: p. 1508-1510
Tubaro A, Miano L. Managing the consequences of obstruction. Eur Urol Suppl, 2002. 1: p. 21–27.
Oelke M, et al., Increase in detrusor wall thickness indicates bladder outlet obstruction (BOO) in men. World J Urol, 2002. 19: p. 443–452.
Levent Işıkay, et al., Lower urinary tract symptoms, prostate volume, uroflowmetry, residual urine volume and bladder wall thickness in Turkish men: a comparative analysis. Int Urol Nephrol, 2007. 39: p. 1131–1135.
Kessler TM, et al., Ultrasound assessment of detrusor thickness in men. Can it predict bladder outlet obstruction and replace pressure flow study? J Urol, 2006. 175: p. 2170–2173.