Cinnamoyl Derivatives from Cordia Platythyrsa and Chemiotaxonomical Value of the Cordia Genus
Science Journal of Chemistry
Volume 4, Issue 3, June 2016, Pages: 36-40
Received: Jun. 6, 2016; Accepted: Jun. 15, 2016; Published: Jun. 30, 2016
Views 3375      Downloads 138
Bernard Dabole, Department of Chemistry, University of Maroua, Maroua, Cameroon
Rostanie Zeukang, Department of Organic Chemistry, University of Yaounde-I, Yaounde, Cameroon
Alex de Theodore Atchade, Department of Organic Chemistry, University of Yaounde-I, Yaounde, Cameroon
Turibio Tabopda, Department of Organic Chemistry, University of Yaounde-I, Yaounde, Cameroon
Benoit Bargui Koubala, Department of Chemistry, University of Maroua, Maroua, Cameroon
Joseph Tanyi Mbafor, Department of Organic Chemistry, University of Yaounde-I, Yaounde, Cameroon
Article Tools
Follow on us
Phytochemical investigation of the roots and stem barks of Cordia platythyrsa (Boraginaceae) had led to the isolation of two new cinnamates, the cordicinnamate A compound 1 and the cordicinnamate B compound 2 along with four known compounds. Their structures were established by spectroscopic analysis mainly FAB and TOF –MS, 1H NMR and 13C NMR, COSY, HMBC, HSQC and by comparison with literature data. The cinnamoyl derivatives were reported for the first time in the Cordia genus. The isolation and identification of cinnamoyl derivatives in cordia genus improve the chemiotaxonomy value in this genus.
Boraginaceae, Cordia Platythyrsa, Cinnamoyl Derivatives, Chemiotaxonomy
To cite this article
Bernard Dabole, Rostanie Zeukang, Alex de Theodore Atchade, Turibio Tabopda, Benoit Bargui Koubala, Joseph Tanyi Mbafor, Cinnamoyl Derivatives from Cordia Platythyrsa and Chemiotaxonomical Value of the Cordia Genus, Science Journal of Chemistry. Vol. 4, No. 3, 2016, pp. 36-40. doi: 10.11648/j.sjc.20160403.12
Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Thirupathi, K., Kumar S., Raju V., Ravikumar B., Krishna D., Mohan G.. A review of medicinal plants of the genus Cordia: their chemistry and pharmacological uses. J. Nat. Rem., 8, 2008, pp. 1-10.
Dalziel, J., Hutchinson, J. The useful plants of west tropical Africa an appendix to the flora of West Africa, 1948, pp 424.
Al-Awadi, F., Srikumar, T., Anim, J., Khan, I. Antiinflammatory Effects of Cordia myxa Fruit on Experimentally Induced Colitis in Rats. Nutrition 17, 2001, pp. 391–396.
Okusa, P., Penge O., Duez, P., Devleeschouwer, M. Direct and indirect antimicrobial effects and antioxidant activity of Cordia gilletii De Wild (Boraginaceae). J. Ethnopharm 112, 2007, pp. 476-481.
Tapondjou, L., Mitaine-offer, A., Sautor M., Tomofumi M., Lacaille-Duboism A. Shingolipids and other constituents from Cordia platythyrsa. Biochem. Syst. and Ecolo. 33, 2005, pp. 1293-1297.
Atchadé, T., Dabolé B., Achyut, A., Kahn, A., Mbafor J., Choudhary M. Chemical Constituents of Cordia Platythyrsa and evaluation of their glycation and urease inhibition activities. J. Nat. Prod. Ind.; 8, 2012, pp. 346-351.
Hutchinson J., Dalziel J. M., «Flora of West Tropical Africa», Mill Bank, Londre, 1963, pp. 317-32.
Somepalli V., Merallapudi S., Alluri V., Golakoti T., Gottumukkala V. Antioxidant and antimicrobial activity evaluation of polyhydroxycinnamic acid ester derivatives, Ind. J. Chem. 45B, 2005, pp. 252-257.
Talla Emmanuel, DaoudaDjibo., Nyemb Jean-Noël, Sophie Laurent, Vander Eist Luce, Dabole Bernard and MbaforTanyi Joseph. Two new compounds from stem barks of Vepris heterophylla (Engl.) R. Let. (Rutaceae). Journal of Chemical and Pharmaceutical Research, 7(7), 2015, pp. 553-557.
Ronchetti D., Impagnatiello F., Guzzetta M., Gasparini L., Borgatti M., Gambari R., Ongni E.. Modulation of INOS expression by a nitric oxide-releasing derivative of the natural antioxidant ferulic acid in activated RAW 264.7 macrophages. European J. Pharm 12, 532, 2006, pp. 162-169.
Faizi S., Ali M., Saleem R., Irfanullah, Bibi S., «Complete 1H and 13C NMR assignments of stigma-5-en-3-O-β-glucoside and its acetyl derivative», Magnetic Resonance Chemistry, 39, 2001, pp.399-405.
Ingólfsdóttir K., Gudmundsdóttir G. F., Ögmundsdóttir H. M., Paulus K., Haraldsdóttir S., Kristinsson H., and Bauer R., «Effects of teuiorin and methyl orsellinate from the lichen Peltigeraleucophlebia on 5-/15-lipoxygenases and proliferation of malignant cell lines in vitro». Phytomedicine, 9, 2002, pp. 654-658.
Rojas I. S., Lotina-Hennsen B., Mata R., «Effect of licheb metabolites on thylakoid electron transport and photophosphorylation in isolated spinach chloroplasts 1». Journal of Natural Products, 63, (2000), 1396-1399.
Sandjo Louis Pergaud, «Sphingolipides, Triterpčnoďdes et autres métabolitessecondaires des variétés sauvage et cultivée de l’espèce Triumfetta cordifolia A. Rich. (Tiliaceae): Transformations chimiques et évaluation des propriétés biologiques de quelques composés isolés», Thèse de Doctorat /Ph.D en Chimie Organique, Université de Yaoundé I- Cameroun, 2009, pp. 33.
Masanori Kuroyanagi, Takahiro Seki, Tatsuo Hayashi, Yoshio Nagashima, Nobuo Kawahara, Setsuko Sekita, and Motoyoshi Satake. «Anti-androgenic Triterpenoids from the Brazilian medicinal plant Cordia multispicata». Chem. Pharm. Bull., 49(8), 2001, pp. 954-957.
Masanori Kuroyanagi, Nobuo Kawahara, Setsuko Sekita, MotoyoshiSatake, Tatsuo Hayashi, Yoichi Takase, and Kazuo Masuda, «Dammarane-type triterpenes from Cordia Spinescens». Journal of Natural Products, 66, 2003, pp. 1307-1312.
Lothar W. Bieber, Hans C. Krebs and Wolfram Schäfer, «Further Meroterpenoid naphthoquinones from cordia corymbosa». Phytochemistry, 35(4), 1994, pp. 1027-1028.
Ioset J. R., Marston A., Gupta M. P., Hostettmann K., «Antifungal and larvicidal cordiaquinones from the roots of Cordia curassavica». Phytochemistry,53, 2000, pp. 613-6
Mori K., Kawano M., Fuchino H., Ooi T., Satake M., Agatsuma Y., Kusumi T., and Sekita S.«Antileishmanial Compounds from Cordia fragrantissima collected in Burma (Myanmar) ». Journal of Natural Product, 71, 2008, pp. 18-21.
Yasmina Aura Lim, Shiho Kojima, Norio Nakamura, Hirotsugu Miyashiro, Hirotoshi Fushimi, Katsuko Komatsu, Masao Hattori, Kunitada Shimotohno, Mahabir P. Gupta and Mireya Correa, « Inhibitory effects of Cordia spinescens extracts and their constituents on reverse transcriptase and protease from human immunodeficiency virus». Phytotherapy research, 11, 1997, pp. 490-495.
Moir M. and Ronald H. Thomson, «Naturally occurring quinines. Part XXII. Terpenoid quinones in Cordia Spp.». Journal of Chemical Society Perkin I., 1973, pp. 1352-1357.
Gary D. Manners and Leonard Jurd, «The Hydroquinone Terpenoids of Cordia alliodora». Journal of Chemical Society Perkin Transcent I, 1997, pp. 405-410.
Srivastava S. K., Srivastava S. D. and Nigam S. S., Lupa-20(29)-ene-3-O-α-L-rhamnopyranoside from the roots of Cordia oblique. J. Indian Chem. Soc., LX, 1983, pp. 202.
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
Tel: (001)347-983-5186