Science Journal of Chemistry
Volume 1, Issue 2, June 2013, Pages: 26-28
Received: May 14, 2013;
Published: Jun. 30, 2013
Views 2573 Downloads 90
Zaytseva O., Kharkiv National Medical University, Biochemistry Department
Viktor Zhukov, Kharkiv National Medical University, Biochemistry Department
Rezunenko Y., Kharkiv National Medical University, Biochemistry Department
Telegin V, Kharkiv National Medical University, Biochemistry Department
Knigavko V., Kharkiv National Medical University, Biochemistry Department
Risovanaya L., Kharkiv National Medical University, Biochemistry Department
The effect of a new group of oligomers on the structural and functional state of erythrocytes, lymphocytes, hepatocytes, splenocytes membranes of rats under subacute experiment conditions was investigated. It is established that the oligomers are able to alter the membrane physical-chemical properties and disrupt the structural and metabolic processes that underlie the formation of pathological states.
Effect of Oligomers on Structural and Functional State of Biomembranes, Science Journal of Chemistry.
Vol. 1, No. 2,
2013, pp. 26-28.
Alon R, Grabovsky V, Feigelson S. Chemokine induction of integrin adhesiveness on rolling and arrested leukocytes local signaling events or global stepwise activation? Microcirculation. 2003;10:297–311.
Baltus T, Weber KS, Johnson Z, Proudfoot AE, Weber C. Oligomerization of RANTES is required for CCR1-mediated arrest but not CCR5-mediated transmigration of leukocytes on inflamed endothelium. Blood. 2003;102:1985–1988.
Gregory KJ, Dong EN, Meiler J, Conn PJ. Allosteric modulation of metabotropic glutamate receptors structural insights and therapeutic potential. Neuropharmacology . 2011;60: 66–81.
Carpino PA, Goodwin B. Diabetes area participation analysis a review of companies and targets described in the 2008 - 2010 patent literature. Expert Opin Ther Pat . 2010;20:1627–1651.
Duma L, Haussinger D, Rogowski M, Lusso P, Grzesiek S. Recognition of RANTES by extracellular parts of the CCR5 receptor. J Mol Biol. 2007;365:1063–1075.
Vasseur C, Rodien P, Beau I, Desroches A, Gerard C, de Poncheville L, Chaplot S, Savagner F, Croue A, Mathieu E, Lahlou N, Descamps P, Misrahi M. A chorionic gonadotropin-sensitive mutation in the folliclestimulating hormone receptor as a cause of familial gestational spontaneous ovarian hyperstimulation syndrome. N Engl J Med . 2003;349: 753–759.
Dragun D, Philippe A, Catar R, Hegner B. Autoimmune mediated Gprotein receptor activation in cardiovascular and renal pathologies. Thromb Haemost . 2009;101:643–648.
Vischer HF, Vink C, Smit MJ. A viral conspiracy hijacking the chemokine system through virally encoded pirated chemokine receptors. Curr Top Microbiol Immunol . 2006;303:121–154.
Katano H, Sata T. Human herpesvirus 8 virology epidemiology and related diseases. Jpn J Infect Dis . 2000;53:137–155.
Penela P, Murga C, Ribas C, Tutor AS, Peregrin S, Mayor F Jr. Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease. Cardiovasc Res . 2006;69:46–56.
Lombardi MS, Kavelaars A, Heijnen CJ. Role and modulation of G protein-coupled receptor signaling in inflammatory processes. Crit Rev Immunol . 2002;22:141–163.
Shichida Y, Imai H. Visual pigment G-protein-coupled receptor for light signals. Cell Mol Life Sci . 1998;54:1299–1315.
Lappano R, Maggiolini M. G protein-coupled receptors novel targets for drug discovery in cancer. Nat Rev Drug Discov . 2011;10:47–60.
Stone LS, Molliver DC. In search of analgesia emerging poles of GPCRs in pain. Mol Interv. 2009;9:234–251.
Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, Steyaert J, Skiniotis G, Weis WI, Sunahara RK, Kobilka BK. Crystal structure of the beta(2) adrenergic receptor-Gs protein complex. Nature . 2011;477:549–555.
Chung KY, Rasmussen SG, Liu T, Li S, DeVree BT, Chae PS, Calinski D, Kobilka BK, Woods VL, Jr., Sunahara RK. Conformational changes in the G protein Gs induced by the beta2 adrenergic receptor. Nature . 2011;477:611–615.