The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity
Changes in cardiovascular system (CVS) under conditions of hypogravity simulated using 7- and 21-day ortho- and antiorthostatic hypokinesia at different angles were studied. The aim of the experiment was selection of informative CVS parameters most sensitive to these conditions. Simultaneous recording of 26 CVS parameters on a spiroartheriocardiorythmograph showed that the most sensitive parameters were blood pressure (BP) variability indexes in functional tests: differences in groups with varying degrees of orthostatic hypokinesia (+ 9.6˚ and + 15˚) were observed starting from the first week of the experiment. By day 21, pronounced changes in the total spectral power of diastolic BP variability were noted in the group exposed to constant antiorthostasis. This parameter significantly surpassed the corresponding value in the groups with milder conditions. Significant increase in the LF component of diastolic BP in groups exposed to severe antiorthostasis and orthostasis was detected. Presumably, autonomic mechanisms affecting the systolic and diastolic BP under conditions of hypogravity simulation are different, at least partially.
The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity, American Journal of Life Sciences. Special Issue: Space Flight Factors: From Cell to Body.
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2015, pp. 48-57.
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