The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity
Changes in cardiovascular system (CVS) under conditions of hypogravity simulated using 7- and 21-day ortho- and antiorthostatic hypokinesia at different angles were studied. The aim of the experiment was selection of informative CVS parameters most sensitive to these conditions. Simultaneous recording of 26 CVS parameters on a spiroartheriocardiorythmograph showed that the most sensitive parameters were blood pressure (BP) variability indexes in functional tests: differences in groups with varying degrees of orthostatic hypokinesia (+ 9.6˚ and + 15˚) were observed starting from the first week of the experiment. By day 21, pronounced changes in the total spectral power of diastolic BP variability were noted in the group exposed to constant antiorthostasis. This parameter significantly surpassed the corresponding value in the groups with milder conditions. Significant increase in the LF component of diastolic BP in groups exposed to severe antiorthostasis and orthostasis was detected. Presumably, autonomic mechanisms affecting the systolic and diastolic BP under conditions of hypogravity simulation are different, at least partially.
The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity, American Journal of Life Sciences. Special Issue:Space Flight Factors: From Cell to Body.
Vol. 3, No. 1-2,
2015, pp. 48-57.
R.M. Baevsky, “Noninvasive methods in space cardiology,” J.Cardiovasc Diagn Proced, No. 14, 1997, pp. 161-171.
R.M. Baevsky, V.M. Baranov, I.I. Funtova, A. Diedrich, A.V. Pashenko, A.G. Chernikova, J. Drescher, J. Jordan, J. Tank. “Autonomic cardiovascular and respiratory control during prolonged spaceflights aboard the International Space Station,” J.Appl Physiol., vol. 103, 2007, No. 1, pp. 156-161.
R.M. Baevsky, I.I. Funtova, A. Diedrich, A.V. Pashchenko, A.G. Chernikova, J. Drescher, V.M. Baranov, J. Tank, “Autonomic function testing on board the ISS - update on "Pneumocard"”, Acta Astronáutica, vol. 61, No. 7-8, 2007, pp. 672-675.
W.H. Cooke, J.E. IV Ames, A.A. Crossman, J.F. Cox, T.A. Kuusela, K.U. Tahvanainen, L.B. Moon, J. Drescher, F.J. Baisch, T. Mano, B.D. Levine, C.G. Blomqvist, D.L. Eckberg, “Nine months in space: effects on human autonomic cardiovascular regulation,” J. Appl Physiol., vol. 89, 2000, pp. 1039–1045.
J.M. Fritsch-Yelle, J.B. Charles, M.M. Jones, M.L. Wood, “Microgravity decreases heart rate and arterial pressure in humans,” J. Appl Physiol.,vol. 80, 1996, pp. 910–914.
P.F. Migeotte, G.K. Prisk, M. Paiva. “Microgravity alters respiratory sinus arrhythmia and short-term heart rate variability in humans,” Am. J. Physiol. Heart Circ. Physiol. vol. 284, 2003, pp. H1995–H2006.
M.V. Pitzalis, F. Mastropasqua, F. Massari, A. Passantino, R. Colombo, A. Mannarini, C. Forleo, P. Rizzon. “Effect of respiratory rate on the relationships between RR interval and systolic blood pressure fluctuations: а frequency-dependent phenomenon,” Cardiovascular Research., vol. 38, 1998, No. 2, pp. 332-339.
C. Julien, S.C. Malpas, Н.М. Stauss, “Sympathetic modulation of blood pressure variability,” J. Hypertens. vol. 19. 2001. pp. 1707-1712.
J.A. Тауlоr, D.L. Eckberg, “Fundamental relations between short-term RR interval and arterial pressure oscillations in humans,” Circulation. vol. 93. 1996. pp. 1527-1532.
B. Silke, D. McAuley, “Accuracy and precision of blood pressure determination with the Finapres: an overview using re-sampling statistics,” J. Hum Hypertens, vol. 12, No. 6, 1998, pp. 403-409.
T.F. Schmidt, J. Wittenhaus, T.F. Steinmetz, P. Piccolo, H. Lüpsen, “Twenty-four-hour ambulatory noninvasive continuous finger blood pressure measurement with PORTAPRES: a new tool in cardiovascular research,” J. Cardiovasc. Pharmacol., vol. 19, 1992, Suppl 6, pp. 117-145.
A.I. Trukhanov, N.B. Pankova, N.N. Khlebnikova & M.Yu. Karganov, “The Use of Spiroarterio¬cardio¬rhythmo¬graphy as a Functional Test for Estimating the State of the Cardiorespiratory System in Adults and Children,” Human Physiology. vol. 33, No. 5, 2007, pp. 585–594.
A.P. Isaev, S.A. Kabanov, A.R. Sabirjanov, “Features of autonomic regulation of wave processes in the central and peripheral of hemodynamic in young athletes (on an example of sambo-wrestling),” Theory and practice of physical training, No. 1, 2002, pp. 40-43. (in Russian).
A.P. Romanchuk, “The Complex Approach to a Multipurpose Estimation of a Sportsmen Condition,” In:“Polysystemic Approach to School, Sport and Environment Medicine”, M. Karganov ed., - OMICS Group eBooks, 2013, - ISBN: 978-1-63278-000-3, pp. 54-86, - DOI: 10.4172, http://esciencecentral.org/ebooks/polysystemic-approach/complex-approach.php
R.M. Baevsky, I.I. Funtova,A.G. Chernikova, “Problems of heart rhythm variability evaluation in Space Medicine.” Heart rate variability: Theoretical background and practical application. Abstracts of the fourth symposium with international participation. November 19-21, 2008, pp. 24-27, Izhevsk, Russia, (in Russian).
A.R. Кiselev, V.I. Gridnev, “Oscillatory processes in autonomic regulation of the cardiovascular system (Review),” Saratov Journal of Medical Scientific Research. vol. 7, 2011, No. 21. pp. 34-39 (in Russian).
S. Bertuglia, A. Colantuoni, M. Intaglietta, “Effects of L-NMMA and indomethacin on arteriolar vasomotion in skeletal muscle microcirculation of conscious and anesthetized hamsters,” Microvasc. Res. vol. 48, 1994, pp. 68-84.
R.M. Baevsky, V.M. Baranov, J. Tank, E. S. Luchitskaya, I.I. Funtova, A.G. Chernikova, “Analysis of heart rhythm variability and assessment of the state of the myocardium during space flights in tests with fixed respiration rate and breath holding.” Heart rate variability: Theoretical background and practical application. Abstracts of the fourth symposium with international participation. November 19-21, 2008, pp. 27-30, Izhevsk, Russia (in Russian).
V. M. Khayutin, E. V. Lukoshkova, “Heart rate oscillations: spectral analysis.” Vestnik Aritmologii. vol. 26, 2002, No. 9, pp. 10-21 (in Russian).
Y. Yan, G. Shen, K. Xie, C. Tang, X. Wu, Q. Xu, J. Liu, J. Song, X. Jiang, E. Luo, “Wavelet analysis of acute effects of static magnetics field on resting skin bloodflow at the nail wall in young men,” Microvasc. Res., vol. 82, 2011, pp. 277-283.
L. Bernardi, C. Porta, G. Casucci, R. Balsamo, N.F. Bernardi, R. Fogari, P. Sleight, “Dynamic interactions between musical, cardiovascular, and cerebral rhythms in humans,” Circulation, vol. 119, 2009, pp. 3171-3180.
Bernardi L., Passino C., Spadacini G., F. Valle, S. Leuzzi, M. Piepoli, P. Sleight, “Arterial baroreceptors as determinants of 0.1 Hz and respiration-related changes in blood pressure and heart rate spectra,” In: “Frontiers of blood pressure and heart rate analysis.” M. Di Rienzo, G. Mancia, G. Parati, A. Pedotti, A. Zanchetti ed., Amsterdam. IOS Press. 1997. pp. 241-252, ISBN: 978-90-5199-312-7(print)/ 978-1-60750-879-3(online), DOI: 10.3233/978-1-60750-879-3-241.
A. Cevese, R. Grasso, R. Poltronieri, F. Schena, “Vascular resistance and arterial pressure low-frequency oscillation in the anesthetized dog,” Am. J. Physiol. vol. 268, 1995, No. 1, pp. H7-H16.
“Internal synchronization of the main 0.1-Hz rhythms in the autonomic control of the cardiovascular system,” A.R. Kiselev, A.B. Bespiatov, O.M. Posnenkova, et al. Fiziologiya Chekoveka, vol. 33, 2007, No. 2, pp. 69-75 (in Russian).
A. I. Krupatkin. “Blood flow oscillations at a frequency of about 0.1 Hz in skin microvessels do not reflect the parasympathetic regulation of their tone,” Fiziologiya Chekoveka, vol. 35, 2007, No. 2, pp. 60–69 (in Russian).
A.A. Grinevich, A.V. Tankanag, N.K. Chemeris, “Role of elasticity of blood vessels in formation of highly amplitude oscillations of a blood flow with frequency of 0.1 Hz,” Mathematical Biology and Bioinformatics, vol. 9, 2014. No. 2, pp. 341-358.
R.L. Cooley, N. Montano, C. Cogliati, P. van de Borne, W. Richenbacher, R. Oren, Somers VK.. “Evidence for a central origin of low-frequency oscillation in RR-interval variability,” Circulation. vol. 98, No. 6, 1998, pp. 556-561.
M. Michaelis, R. Göder, H.J. Häbler, and W. Jänig. “Properties of afferent nerve fibers supplying the saphenous vein in the cat,” J. Physiol., vol. 474, 1994, No. 2, pp. 233–243.
V.M. Khayutin, R.S. Sonina, E.V. Lukoshkova, Central organization of vasomotor control.” Moscow, Meditsina, 1977, p. 352 (in Russian).
Yates BT. “Vestibular influences on the autonomic nervous system.” Ann NY Acad Sci 1996; vol. 781: pp. 458-473.
R.M. Baevsky, O. I. Kirillov, S. Z. Kletskin. “Mathematical analysis of changes in heart rate during stress.” Moscow, 1984 (in Russian).
A.V. Elfimov. “Influence of subsegental compartments of the autonomic nervous system on heart rate,” A.V. Elfimov, I.V. Filippov. Mechanisms of Visceral System Functioning. St.Petersburg. I.P.Pavlov Institute of Physiology, Russian Academy of Sciences, 2001, pp. 118-119 (in Russian).
N. B. Khaspekova, “Regulation of heart rhythm variability in healthy individuals and patients with psychogenic and organic pathologies of the brain.” Doctor of Medical Science Dissertation. Moscow, 1996, p. 217 (in Russian).